scholarly journals Automatic patient positioning and gating window settings in respiratory-gated stereotactic body radiation therapy for pancreatic cancer using fluoroscopic imaging

2018 ◽  
Vol 19 (2) ◽  
pp. 74-82 ◽  
Author(s):  
Niclas Pettersson ◽  
Daniel Simpson ◽  
Todd Atwood ◽  
Jona Hattangadi-Gluth ◽  
James Murphy ◽  
...  



BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Daniel L. P. Holyoake ◽  
Elizabeth Ward ◽  
Derek Grose ◽  
David McIntosh ◽  
David Sebag-Montefiore ◽  
...  


2017 ◽  
Vol 49 (2) ◽  
pp. 116-123 ◽  
Author(s):  
Jonathan W. Lischalk ◽  
Aidan Burke ◽  
Jessica Chew ◽  
Christen Elledge ◽  
Marie Gurka ◽  
...  


2022 ◽  
Vol 29 (1) ◽  
pp. 308-320
Author(s):  
Abhinav V. Reddy ◽  
Shuchi Sehgal ◽  
Colin S. Hill ◽  
Lei Zheng ◽  
Jin He ◽  
...  

Objective: To report on clinical outcomes and toxicity in older (age ≥ 70 years) patients with localized pancreatic cancer treated with upfront chemotherapy followed by stereotactic body radiation therapy (SBRT) with or without surgery. Methods: Endpoints included overall survival (OS), local progression-free survival (LPFS), distant metastasis-free survival (DMFS), progression-free survival (PFS), and toxicity. Results: A total of 57 older patients were included in the study. Median OS was 19.6 months, with six-month, one-year, and two-year OS rates of 83.4, 66.5, and 42.4%. On MVA, resection status (HR: 0.30, 95% CI 0.12–0.91, p = 0.031) was associated with OS. Patients with surgically resected tumors had improved median OS (29.1 vs. 7.0 months, p < 0.001). On MVA, resection status (HR: 0.40, 95% CI 0.17–0.93, p = 0.034) was also associated with PFS. Patients with surgically resected tumors had improved median PFS (12.9 vs. 1.6 months, p < 0.001). There were 3/57 cases (5.3%) of late grade 3 radiation toxicity and 2/38 cases (5.3%) of Clavien-Dindo grade 3b toxicity in those who underwent resection. Conclusion: Multimodality therapy involving SBRT is safe and feasible in older patients with localized pancreatic cancer. Surgical resection was associated with improved clinical outcomes. As such, older patients who complete chemotherapy should not be excluded from aggressive local therapy when possible.





2018 ◽  
Vol 8 (5) ◽  
pp. e312-e321 ◽  
Author(s):  
Stephen James Ramey ◽  
Kyle R. Padgett ◽  
Narottam Lamichhane ◽  
Hanmath J. Neboori ◽  
Deukwoo Kwon ◽  
...  


2018 ◽  
Vol 127 ◽  
pp. S394
Author(s):  
X. Zhu ◽  
S. Dongchen ◽  
J. Xiaoping ◽  
C. Yangsen ◽  
S. Yuxin ◽  
...  


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