scholarly journals The benefits evaluation of abdominal deep inspiration breath hold based on knowledge‐based radiotherapy treatment planning for left‐sided breast cancer

2020 ◽  
Vol 21 (10) ◽  
pp. 89-96
Author(s):  
Jiaqi Xu ◽  
Jiazhou Wang ◽  
Feng Zhao ◽  
Weigang Hu ◽  
Guorong Yao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Treatment Planning ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Radiotherapy Treatment Planning ◽  
Deep Inspiration Breath Hold ◽  
Knowledge Based ◽  
Benefits Evaluation ◽  
Radiotherapy Treatment

scholarly journals The benefits evaluation of abdominal deep inspiration breath hold based on knowledge-based radiotherapy treatment planning for left-sided breast cancer

2020 ◽  
Author(s):  
Jiaqi Xu ◽  
Jiazhou Wang ◽  
Feng Zhao ◽  
Weigang Hu ◽  
Luyi Bu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Treatment Planning ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Breast Cancer Patients ◽  
Radiotherapy Treatment Planning ◽  
Deep Inspiration Breath Hold ◽  
Knowledge Based ◽  
Radiotherapy Treatment

Abstract Purpose Study the impact of abdominal deep inspiration breath hold (DIBH) technique on knowledge-based radiotherapy treatment planning for left-sided breast cancer to guide the application of DIBH radiotherapy technology. Methods and Materials Two kernel density estimation (KDE) models were developed based on 40 left-sided breast cancer patients with two CT acquisitions of free breathing (FB-CT) and DIBH (DIBH-CT). Each KDE model was used to predict DVHs based on DIBH-CT and FB-CT for another 10 new patients similar to our training datasets. The predicted DVHs were taken as a substitute to dose constraints and objective functions in the Eclipse treatment planning system, with the same requirements for the planning target volume (PTV). The mean doses to the heart, the left anterior descending coronary artery (LADCA) and the ipsilateral lung were evaluated and compared using the T-test among clinical plans, KDE predictions, and KDE plans.Results Our study demonstrated that the KDE model can generate deliverable simulations equivalent to clinically applicable plans. The T-test was applied to test the consistency hypothesis on another 10 left-sided breast cancer patients. In cases of the same breathing status, there was no statistically significant difference between the predicted and the clinical plans for all clinically relevant dose volume histogram (DVH) indices (p>0.05), and all predicted DVHs can be transferred into deliverable plans. For DIBH-CT images, significant differences were observed in Dmean between FB model predictions and the clinical plans (p<0.05). DIBH model prediction cannot be optimized to a deliverable plan based on FB-CT, with a counsel of perfection. Conclusion This study demonstrated that the KDE prediction results were well fitted for the same breathing condition but degrade with different breathing conditions. The benefits of DIBH can be evaluated quickly and effectively by the specific knowledge-based treatment planning for left-sided breast cancer radiotherapy. This study will help to further realize the goal of automatic treatment planning.

PH-0163: Harmonization of breast cancer radiotherapy treatment planning in the Netherlands

2020 ◽  
Vol 152 ◽  
pp. S77-S78
Author(s):  
M. Verhoeven ◽  
M. Sangen van der ◽  
C. Hurkmans ◽  
L. Boersma ◽  
K. Verhoeven ◽  
...  
Keyword(s):  
Breast Cancer ◽  
The Netherlands ◽  
Treatment Planning ◽  
Radiotherapy Treatment Planning ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Radiotherapy Treatment

PD-0180: Interim Report from the SAVE HEART Study: deep inspiration breath-hold in left-sided breast cancer

2020 ◽  
Vol 152 ◽  
pp. S88
Author(s):  
S. Schönecker ◽  
A. Gaasch ◽  
M. Pazos ◽  
D. Reitz ◽  
M. Braun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Interim Report ◽  
Deep Inspiration Breath Hold ◽  
Heart Study

Deep-inspiration breath hold radiotherapy in patients with left-sided breast cancer after partial mastectomy

2021 ◽  
Vol 100 (4) ◽  
Keyword(s):  
Breast Cancer ◽  
Radiation Dose ◽  
Organs At Risk ◽  
Left Lung ◽  
Free Breathing ◽  
Partial Mastectomy ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Deep Inspiration Breath Hold ◽  
Dose Volume Histograms

Introduction: The purpose of this study was to compare the radiation dose to organs at risk for deep-inspiration breath hold (DIBH) and free-breathing (FB) radiotherapy in patients with lef-sided breast cancer undergoing adjuvant radiotherapy after partial mastectomy. Methods: One hundred patients with left-sided breast cancer underwent DIBH and FB planning computed tomography scans, and the 2 techniques were compared. Dose-volume histograms were analyzed for heart, left anterior descending coronary artery (LAD), and left lung. Results: Radiation dose to heart, LAD, and left lung was significantly lower for DIBH than for free breathing plans. The median mean heart dose for DIBH technique in comparison with FB was 1.21 Gy, and 3.22 Gy respectively; for LAD, 4.67 versus 24.71 Gy; and for left lung 8.32 Gy versus 9.99 Gy. Conclusion: DIBH is an effective technique to reduce cardiac and lung radiation exposure.

Deep inspiration breath-hold for patients with left-sided breast cancer – A one fits all approach? A prospective analysis of patient selection using dosimetrical and practical aspects

2021 ◽  
pp. 20210295
Author(s):  
Christina Schröder ◽  
Sebastian Kirschke ◽  
Eyck Blank ◽  
Sophia Rohrberg ◽  
Robert Förster ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Left Lung ◽  
Free Breathing ◽  
Lymphatic Drainage ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Deep Inspiration Breath Hold ◽  
Patient Preparation ◽  
Treatment Plans ◽  
Planning Ct

Objective: To prospectively analyze the feasibility of an algorithm for patient preparation, treatment planning and selection for deep inspiration breath-hold (DIBH) treatment of left-sided breast cancer. Methods: From 02/2017 to 07/2019, 135 patients with left-sided breast cancer were selected and prepared for radiotherapy in DIBH. 99 received radiotherapy for the breast alone and 36 for the breast including the lymphatic drainage (RNI). Treatment plans DIBH and free breathing (FB) were calculated. Dosimetrical analyses were performed and criteria were defined to assess whether a patient would dosimetrically profit from DIBH. Results: Of the 135 patients, 97 received a DIBH planning CT and 72 were selected for treatment in DIBH according to predefined criteria. When using DIBH there was a mean reduction of the DmeanHeart of 2.8 Gy and DmeanLAD of 4.2 Gy. seven patients did not benefit from DIBH regarding DmeanHeart, 23 regarding DmeanLAD. For the left lung the V20Gy was reduced by 4.9%, the V30Gy by 2.7% with 15 and 29 patients not benefitting from DIBH, respectively. In the 25 patients treated in FB, the benefit of DIBH would have been lower than for patients treated with DIBH (ΔDmeanHeart0.7 Gy vs 3.4 Gy). Conclusion: Dosimetrically, DIBH is no “one fits all” approach. However, there is a statistically significant benefit when looking at a larger patient population. DIBH should be used for treatment of left-sided breast cancer in patients fit for DIBH. Advances in knowledge: This analysis offers a well-designed dosimetrical analysis in patients treated with DIBH radiotherapy in an “every day” cohort.

scholarly journals Dose variability in different lymph node levels during locoregional breast cancer irradiation: the impact of deep-inspiration breath hold

2018 ◽  
Vol 195 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Montserrat Pazos ◽  
Alba Fiorentino ◽  
Aurélie Gaasch ◽  
Stephan Schönecker ◽  
Daniel Reitz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Deep Inspiration Breath Hold ◽  
Dose Variability ◽  
The Impact ◽  
Cancer Irradiation
Sign in / Sign up

Export Citation Format

Share Document