Mismatched base pairs were significantly destabilized in the hydrated ionic liquid (IL) relative to those in aqueous buffer. The molecular beacon that forms a triplex with a conserved HIV-1 sequence specifically detected the target duplex with 10,000-fold sequence selectivity in IL. Moreover, the molecular beacon was protected from a contaminating nuclease in IL.
This paper proposes a novel soft ionic liquid (IL) electrically functional device that displays resistive memory characteristics using poly(acrylic acid) partial sodium salt (PAA-Na+:H2O) solution gel and sodium hydroxide (NaOH) in a thin polydimethylsiloxane (PDMS) cylindrical microchannel.
Comparable Stability of Hoogsteen and Watson–Crick Base Pairs in Ionic Liquid Choline Dihydrogen Phosphate
