scholarly journals Activation of hypothalamic AMPK ameliorates metabolic complications of experimental arthritis

2021 ◽  
Author(s):  
Patricia Seoane‐Collazo ◽  
Eva Rial‐Pensado ◽  
Ánxela Estévez‐Salguero ◽  
Edward Milbank ◽  
Lucía García‐Caballero ◽  
...  
Keyword(s):  
Experimental Arthritis ◽  
Metabolic Complications

Efficacy and safety of volanesorsen for the treatment of metabolic complications in patients with familial partial lipodystrophy: results of the BROADEN study

2020 ◽  
Author(s):  
Louis O’Dea ◽  
Joseph Tami ◽  
Veronica Alexander ◽  
Lynnetta Watts ◽  
Eunju Hurh ◽  
...  
Keyword(s):  
Efficacy And Safety ◽  
Metabolic Complications ◽  
Partial Lipodystrophy ◽  
Familial Partial Lipodystrophy

Atypical Antipsychotics and Metabolic Complications

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 714-P ◽  
Author(s):  
MUNAZA AKUNJEE ◽  
SHRUTI M. GANDHI ◽  
ERIC NYLEN
Keyword(s):  
Atypical Antipsychotics ◽  
Metabolic Complications

Impact of Prolactin Hipersecrey on Glucid and Lipid Metabolisms

2019 ◽  
Vol 70 (5) ◽  
pp. 1603-1607
Author(s):  
Elena Ionescu ◽  
Bogdan Virgil Cotoi ◽  
Anca Ganescu
Keyword(s):  
Cranial Nerves ◽  
Pituitary Tumors ◽  
Optic Chiasm ◽  
Anterior Lobe ◽  
Visual Field Defects ◽  
Large Tumor ◽  
Metabolic Complications ◽  
Clinical Onset ◽  
Vision Defects ◽  
Upper Level

Pituitary is a common terrain for the appearance of tumoral changes, representing the origin of about 15% of all intracranial tumors [13]. These tumors are, for the most part, histologically benign, as they arise from hormone secreting cells in the anterior lobe. Therefore, the aim of the paper is to specify the clinical and paraclinical clinical onset characteristics, the evolutionary peculiarities, as well as the metabolic complications secondary to the prolactin hypersecretion. The effects of prolactin-secreting pituitary tumors may occur as a result of mass effects of tumors or even hyperprolactinaemia. Because microadenomas are intrathecal, visual defects may not occur, but headaches occur more often (50%) than normal (27%) [1, 6]. A large tumor that extends beyond the limbs of the turkey can cause headaches and vision defects. The classical presentation is bitemporal hemianopsia due to the compression of the optic chiasm from a tumor that extends to the upper level. If chiasma is prefixed or if the tumor extends posteriorly, compression of a single optical system results in visual field defects similar. The lateral extension in the cavernous sinus can lead to the illness of the oculomotor function involving the cranial nerves III, IV and VI and the branches V1 and V2 of the cranial nerve V, alone or in combinations.

Semi-Quantitative Ultrasonographic Evaluation of NAFLD

2020 ◽  
Vol 26 (32) ◽  
pp. 3915-3927 ◽  
Author(s):  
Stefano Ballestri ◽  
Claudio Tana ◽  
Maria Di Girolamo ◽  
Maria Cristina Fontana ◽  
Mariano Capitelli ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Imaging Techniques ◽  
Metabolic Complications ◽  
Nonalcoholic Fatty Liver ◽  
Non Invasive ◽  
Increased Risk ◽  
Risk Of Progression ◽  
Progressive Liver Disease

: Nonalcoholic fatty liver disease (NAFLD) embraces histopathological entities ranging from the relatively benign simple steatosis to the progressive form nonalcoholic steatohepatitis (NASH), which is associated with fibrosis and an increased risk of progression to cirrhosis and hepatocellular carcinoma. NAFLD is the most common liver disease and is associated with extrahepatic comorbidities including a major cardiovascular disease burden. : The non-invasive diagnosis of NAFLD and the identification of subjects at risk of progressive liver disease and cardio-metabolic complications are key in implementing personalized treatment schedules and follow-up strategies. : In this review, we highlight the potential role of ultrasound semiquantitative scores for detecting and assessing steatosis severity, progression of NAFLD, and cardio-metabolic risk. : Ultrasonographic scores of fatty liver severity act as sensors of cardio-metabolic health and may assist in selecting patients to submit to second-line non-invasive imaging techniques and/or liver biopsy.

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