scholarly journals Comparing growth in linguistic comprehension and reading comprehension in school-aged children with autism versus typically developing children

2017 ◽  
Vol 11 (4) ◽  
pp. 624-635 ◽  
Author(s):  
Ryan P. Grimm ◽  
Emily J. Solari ◽  
Nancy S. McIntyre ◽  
Matthew Zajic ◽  
Peter C. Mundy
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andrea Cavallo ◽  
Luca Romeo ◽  
Caterina Ansuini ◽  
Francesca Battaglia ◽  
Lino Nobili ◽  
...  

AbstractFailure to develop prospective motor control has been proposed to be a core phenotypic marker of autism spectrum disorders (ASD). However, whether genuine differences in prospective motor control permit discriminating between ASD and non-ASD profiles over and above individual differences in motor output remains unclear. Here, we combined high precision measures of hand movement kinematics and rigorous machine learning analyses to determine the true power of prospective movement data to differentiate children with autism and typically developing children. Our results show that while movement is unique to each individual, variations in the kinematic patterning of sequential grasping movements genuinely differentiate children with autism from typically developing children. These findings provide quantitative evidence for a prospective motor control impairment in autism and indicate the potential to draw inferences about autism on the basis of movement kinematics.


MANUSYA ◽  
2014 ◽  
Vol 17 (1) ◽  
pp. 1-21
Author(s):  
Jeamjai Jeeraumporn ◽  
Pattama Patpong

The objective of this study was to compare experiential grammar in the narrative discourse of thirty typically developing Thai children and thirty Thai children with autism in elementary grades 1 to 3. Data was compiled by asking subjects to tell a narrative discourse from a wordless storybook "A Boy, a Dog, and a Frog” (Mayer 1967). Data was analyzed based on the Systemic Functional Linguistics approach and focused on experiential mode of meaning concerned with the system of Transitivity. The results revealed that children with autism used fewer clause complexes and clause simplexes than typically developing children. For the system of Transitivity, it was found that children with autism used less modified nominal groups as the Participant especially in grade 2 and 3 and they used a smaller number and less variety of process types; used a lower percentage of mental, behavioral and verbal processes; and used a lower percentage of serial verb constructions. Children with autism, especially those in grades 2 and 3, used a smaller variety of circumstance types; and used a lower percentage of clauses with complex circumstances.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Dina Tell ◽  
Denise Davidson ◽  
Linda A. Camras

Eye gaze direction and expression intensity effects on emotion recognition in children with autism disorder and typically developing children were investigated. Children with autism disorder and typically developing children identified happy and angry expressions equally well. Children with autism disorder, however, were less accurate in identifying fear expressions across intensities and eye gaze directions. Children with autism disorder rated expressions with direct eyes, and 50% expressions, as more intense than typically developing children. A trend was also found for sad expressions, as children with autism disorder were less accurate in recognizing sadness at 100% intensity with direct eyes than typically developing children. Although the present research showed that children with autism disorder are sensitive to eye gaze direction, impairments in the recognition of fear, and possibly sadness, exist. Furthermore, children with autism disorder and typically developing children perceive the intensity of emotional expressions differently.


2020 ◽  
Author(s):  
Kathryn Hollowood-Jones ◽  
James B. Adams ◽  
Devon M. Coleman ◽  
Sivapriya Ramamoorthy ◽  
Stephan Melnyk ◽  
...  

Abstract Background: Previous research studies have demonstrated abnormalities in the metabolism of mothers of young children with autism.Method: Metabolic analysis was performed on blood samples from 30 mothers of young children with Autism Spectrum Disorder (ASD-M) and from 29 mothers of young typically-developing children (TD-M). Targeted metabolic analysis focusing on the folate one-carbon metabolism (FOCM) and the transsulfuration pathway (TS) as well as broad metabolic analysis were performed. Statistical analysis of the data involved both univariate and multivariate statistical methods.Results: Univariate analysis revealed significant differences in 5 metabolites from the folate one-carbon metabolism and the transsulfuration pathway and differences in an additional 48 metabolites identified by broad metabolic analysis, including lower levels of many carnitine-conjugated molecules. Multivariate analysis with leave-one-out cross-validation allowed classification of samples as belonging to one of the two groups of mothers with 93% sensitivity and 97% specificity with five metabolites. Furthermore, each of these five metabolites correlated with 8-15 other metabolites indicating that there are five clusters of correlated metabolites. In fact, all but 5 of the 50 metabolites with the highest area under the receiver operating characteristic curve were associated with the five identified groups. Many of the abnormalities appear linked to low levels of folate, vitamin B12, and carnitine-conjugated molecules.Conclusions: Mothers of children with ASD have many significantly different metabolite levels compared to mothers of typically developing children at 2-5 years after birth.


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