Penalized estimation in latent Markov models, with application to monitoring serum calcium levels in end-stage kidney insufficiency

2017 ◽  
Vol 59 (5) ◽  
pp. 1035-1046 ◽  
Author(s):  
Alessio Farcomeni
Keyword(s):  
Serum Calcium ◽  
Markov Models ◽  
Penalized Estimation ◽  
Kidney Insufficiency ◽  
End Stage

scholarly journals Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease on Maintenance Haemodialysis

2019 ◽  
Vol 9 (1) ◽  
pp. 59-62
Author(s):  
Muhammad Abdur Razzak ◽  
Debasish Kumar Saha ◽  
Muhammad Ehsan Jalil ◽  
Mohammad Omar Faruque Miah ◽  
Abu Noim Md Abdul Hai ◽  
...  
Keyword(s):  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Aortic Stiffness ◽  
Serum Phosphate ◽  
Serum Phosphate Level ◽  
Maintenance Haemodialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: The stiffness of the large elastic arteries increase the morbidity and mortality. The purpose of the present study was to estimate the risk of aortic stiffness among end stage renal disease patients on maintenance haemodialysis. Methods: This cross-sectional study was carried out in the Department of Nephrology at National Institute of Kidney Diseases and Urology (NIKDU), Dhaka and National Institute of Cardiovascular Disease and Hospital (NICVD), Dhaka, Bangladesh from January 2013 to December 2014 for a period of two years. Chronic kidney disease in stage 5 [CKD-5(D)] patients older than 18 years on maintenance haemodialysis (MHD) for more than 3 months were designated as case group and age and sex matched non CKD patients were considered as control group. Serum calcium, serum albumin, serum phosphate and iPTH were estimated by semi-automated biochemistry analyzer from the Department of Biochemistry of NIKDU, Dhaka and NICVD, Dhaka. Plain Xray abdomen in lateral view was performed for all patients. Result: A total number of 100 patients were enrolled for this study of which 50 patients were in end stage renal disease (ESRD) group and the rest 50 patients were in non-CKD group. Mean (±SD) aortic stiffness index was significantly higher (P<0.001) among ESRD population (3.27±1.70) compared to non CKD group of population (2.00±0.73). Mean (±SD) serum calcium (corrected) level was significantly high (P<0.001) in ESRD patients (9.79±0.87) compared to non CKD group of population (9.13±0.70). Mean (±SD) serum phosphate level was significantly higher (P<0.001) in ESRD patients (5.71±0.96) compared to non CKD group of population (4.20±0.59). However, mean (±SD) iPTH level showed no significant difference between ESRD (25.33±51.98) and non CKD group of population (38.53±19.52). Conclusion: In conclusion, aortic stiffness is significantly higher among ESRD subjects. Birdem Med J 2019; 9(1): 59-62

scholarly journals Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease under Maintenance Haemodialysis

2019 ◽  
Vol 14 (2) ◽  
pp. 67-70
Author(s):  
Md Rasul Amin ◽  
Abdur Razzak ◽  
GM Sadik Hasan ◽  
ANM Abdul Hai ◽  
Chayan Kumar Singho ◽  
...  
Keyword(s):  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Aortic Stiffness ◽  
Serum Phosphate ◽  
Serum Phosphate Level ◽  
Maintenance Haemodialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: The stiffness of the large elastic arteries increase the morbidity and mortality. Objective: The purpose of the present study was to estimate the risk of aortic stiffness among end stage renal disease patients under maintenance haemodialysis. Methodology: This case-control study was carried out in the Department of Nephrology at National Institute of Kidney Diseases and Urology (NIKDU), Dhaka and National Institute of Cardiovascular Disease and Hospital (NICVD), Dhaka, Bangladesh from January 2013 to December 2014 for a period of two (02) years. Chronic kidney disease in stage 5 [CKD-5(D)] patients older than 18 years on maintenance haemodialysis (MHD) for more than 3 months were designated as case group and age and sex matched non CKD patients were considered as control group. Serum calcium, serum albumin, serum phosphate and iPTH were estimated by semi-automated biochemistry analyzer from the Department of Biochemistry of NIKDU, Dhaka and NICVD, Dhaka. Plain X-ray abdomen in lateral view was performed for all patients. Result: A total number of 100 patients were enrolled for this study of which 50 patients were in end stage renal disease (ESRD) group and the rest 50 patients were in non-CKD group. Mean (±SD) aortic stiffness index was significantly higher (P<0.001) among ESRD population (3.27±1.70) compared to non CKD group of population (2.00±0.73). Mean (±SD) serum calcium (corrected) level was significantly high (P<0.001) in ESRD patients (9.79±0.87) compared to non CKD group of population (9.13±0.70). Mean (±SD) serum phosphate level was significantly higher (P<0.001) in ESRD patients (5.71±0.96) compared to non CKD group of population (4.20±0.59). However, mean (±SD) iPTH level showed no significant difference between ESRD (25.33±51.98) and non CKD group of population (38.53±19.52). Conclusion: In conclusionaortic stiffness is significantly higher among ESRD subjects. University Heart Journal Vol. 14, No. 2, Jul 2018; 67-70

Biochemical Changes following Parathyroidectomy

1993 ◽  
Vol 16 (10) ◽  
pp. 700-703 ◽  
Author(s):  
P.K.G. Chandran ◽  
T.J. Ulahannan ◽  
M. Skiles
Keyword(s):  
Alkaline Phosphatase ◽  
Serum Calcium ◽  
Serum Alkaline Phosphatase ◽  
Inorganic Phosphorus ◽  
Biochemical Changes ◽  
Postoperative Hypocalcemia ◽  
Subtotal Parathyroidectomy ◽  
Osteoblastic Activity ◽  
End Stage ◽  
Phosphorus Levels

Biochemical changes that had appeared after subtotal parathyroidectomy (PTx) in 26 patients with end-stage renal failure were observed. The volume of excised parathyroid glands was also measured. Serum calcium and inorganic phosphorus levels fell after PTx; only to rise in due course. Serum alkaline phosphatase levels rose after PTx, reaching a peak by the 14th postoperative day. These elevated levels returned to normal range at about three months after PTx. Strong correlation was noted among the degree of postoperative hypocalcemia, and increase in serum alkaline phosphatase, but not between absolute pre or postoperative alkaline phosphatase levels and changes in serum calcium or phosphorus concentrations. Nevertheless, significant correlation was seen between pre-PTx levels of alkaline phosphatase and its short-lived postoperative rise, indicating hastened osteoblastic activity.

scholarly journals Penalized estimation of flexible hidden Markov models for time series of counts

METRON ◽  
2019 ◽  
Vol 77 (2) ◽  
pp. 87-104 ◽  
Author(s):  
Timo Adam ◽  
Roland Langrock ◽  
Christian H. Weiß
Keyword(s):  
Time Series ◽  
Hidden Markov Models ◽  
Markov Models ◽  
Hidden Markov ◽  
Time Series Of Counts ◽  
Penalized Estimation

scholarly journals The relation between vitamin D status and anemia in patients with end stage renal disease on regular hemodialysis

2021 ◽  
Vol 7 (1) ◽  
pp. e15-e15
Author(s):  
Essam Nour el Din Afifi ◽  
Ahmed Mohamed Tawfik ◽  
Essam Eldin Rashed Saeed Abdulkhalek ◽  
Lina Essam Khedr
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Iron Status ◽  
Vitamin D Status ◽  
Vitamin D Levels ◽  
Stage Renal Disease ◽  
End Stage ◽  
Regular Hemodialysis

Introduction: Anemia is a common complication in end-stage renal disease (ESRD) patients on regular hemodialysis (HD). There has been a lot of interest recently in the non-classical effects of 25(OH) vitamin D (calcidiol), including its association with erythropoiesis and anemia pathogenesis. Objectives: To study the relation between anemia and vitamin D status in patients on regular HD Results: This study is a cross-sectional study that included 90 patients on regular HD. Vitamin D status was classified into deficient (<20 ng/ mL), insufficient (20-30 ng/mL) and sufficient (>30 ng/mL). The level of vitamin D measured in the patients ranged between 3.5 to 66 ng/mL with median of 16.35 ng/mL. There were statistically significant positive correlations between vitamin D levels and the level of hemoglobin (P<0.001), serum calcium levels (P<0.001) and serum PO4 levels (P=0.023). Higher hemoglobin levels were statistically related to both higher vitamin D values (P<0.001) and higher serum calcium concentration P<0.001). Meanwhile, a significant negative correlation was found between hemoglobin levels and serum PTH values (P<0.001). Conclusion: There was a significant association between the status of vitamin D and the level of hemoglobin in dialysis population who were studied, independent from iron status. other associations with hemoglobin levels included PTH level and calcium.

Serum phosphate is an important determinant of corrected serum calcium in end-stage kidney disease

Nephrology ◽  
2009 ◽  
Vol 14 (4) ◽  
pp. 383-388 ◽  
Author(s):  
PAOLO FERRARI ◽  
RICHARD SINGER ◽  
AANCHAL AGARWAL ◽  
ANNE HURN ◽  
MARY A TOWNSEND ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Serum Calcium ◽  
Important Determinant ◽  
Serum Phosphate ◽  
End Stage Kidney Disease ◽  
End Stage
Sign in / Sign up

Export Citation Format

Share Document