scholarly journals Model-Based Investigation on the Mass Transfer and Adsorption Mechanisms of Mono-Pegylated Lysozyme in Ion-Exchange Chromatography

2017 ◽  
Vol 12 (9) ◽  
pp. 1700255 ◽  
Author(s):  
Josefine Morgenstern ◽  
Gang Wang ◽  
Pascal Baumann ◽  
Jürgen Hubbuch
Keyword(s):  
Mass Transfer ◽  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Adsorption Mechanisms ◽  
Model Based

Model-based prediction of monoclonal antibody retention in ion-exchange chromatography

2013 ◽  
Vol 1298 ◽  
pp. 17-25 ◽  
Author(s):  
Bertrand Guélat ◽  
Lydia Delegrange ◽  
Pascal Valax ◽  
Massimo Morbidelli
Keyword(s):  
Monoclonal Antibody ◽  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Model Based

Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step

2011 ◽  
Vol 35 (1) ◽  
pp. 183-190 ◽  
Author(s):  
K. Westerberg ◽  
E. Broberg Hansen ◽  
M. Degerman ◽  
T. Budde Hansen ◽  
B. Nilsson
Keyword(s):  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Model Based ◽  
Chromatography Step

Model-based integrated optimization and evaluation of a multi-step ion exchange chromatography

2014 ◽  
Vol 136 ◽  
pp. 207-222 ◽  
Author(s):  
Thiemo C. Huuk ◽  
Tobias Hahn ◽  
Anna Osberghaus ◽  
Jürgen Hubbuch
Keyword(s):  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Integrated Optimization ◽  
Model Based

Model based robustness analysis of an ion-exchange chromatography step

2007 ◽  
Vol 1138 (1-2) ◽  
pp. 109-119 ◽  
Author(s):  
Niklas Jakobsson ◽  
Marcus Degerman ◽  
Emelie Stenborg ◽  
Bernt Nilsson
Keyword(s):  
Ion Exchange ◽  
Robustness Analysis ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Model Based ◽  
Chromatography Step

Ion exchange chromatography of amino acids.Analysis of diffusion (Mass transfer) mechanisms

1960 ◽  
Vol 32 (13) ◽  
pp. 1782-1792 ◽  
Author(s):  
Paul B. Hamilton ◽  
Donald C. Bogue ◽  
Roberta A. Anderson
Keyword(s):  
Mass Transfer ◽  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Diffusion Mass Transfer ◽  
Diffusion Mass ◽  
Transfer Mechanisms

Studies on an Inhibitor of Plasminogen Activation in Human Serum

1973 ◽  
Vol 30 (02) ◽  
pp. 414-424 ◽  
Author(s):  
Ulla Hedner
Keyword(s):  
Ion Exchange ◽  
Human Serum ◽  
Antithrombin Iii ◽  
Gel Filtration ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Specific Adsorption ◽  
Partial Purification ◽  
Plasminogen Activation ◽  
Preparative Electrophoresis

SummaryA procedure is described for partial purification of an inhibitor of the activation of plasminogen by urokinase and streptokinase. The method involves specific adsorption of contammants, ion-exchange chromatography on DEAE-Sephadex, gel filtration on Sephadex G-200 and preparative electrophoresis. The inhibitor fraction contained no antiplasmin, no plasminogen, no α1-antitrypsin, no antithrombin-III and was shown not to be α2 M or inter-α-inhibitor. It contained traces of prothrombin and cerulo-plasmin. An antiserum against the inhibitor fraction capable of neutralising the inhibitor in serum was raised in rabbits.

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