Studies on an Inhibitor of Plasminogen Activation in Human Serum
1973 ◽
Vol 30
(02)
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pp. 414-424
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Keyword(s):
SummaryA procedure is described for partial purification of an inhibitor of the activation of plasminogen by urokinase and streptokinase. The method involves specific adsorption of contammants, ion-exchange chromatography on DEAE-Sephadex, gel filtration on Sephadex G-200 and preparative electrophoresis. The inhibitor fraction contained no antiplasmin, no plasminogen, no α1-antitrypsin, no antithrombin-III and was shown not to be α2 M or inter-α-inhibitor. It contained traces of prothrombin and cerulo-plasmin. An antiserum against the inhibitor fraction capable of neutralising the inhibitor in serum was raised in rabbits.
2021 ◽
Vol 13
(2)
◽
pp. 107-112
1968 ◽
Vol 33
(3)
◽
pp. 788-800
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1988 ◽
Vol 55
(2-3)
◽
pp. 149-157
◽
1990 ◽
Vol 36
(11)
◽
pp. 1906-1910
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Keyword(s):