Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies

2010 ◽  
Vol 106 (5) ◽  
pp. 774-783 ◽  
Author(s):  
Laetitia Malphettes ◽  
Yevgeniy Freyvert ◽  
Jennifer Chang ◽  
Pei-Qi Liu ◽  
Edmond Chan ◽  
...  
Keyword(s):  
Cell Lines ◽  
Zinc Finger ◽  
Zinc Finger Nucleases ◽  
Cho Cell ◽  
Highly Efficient

scholarly journals Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle

Cell Research ◽  
2011 ◽  
Vol 21 (11) ◽  
pp. 1638-1640 ◽  
Author(s):  
Shengli Yu ◽  
Junjie Luo ◽  
Zhiyuan Song ◽  
Fangrong Ding ◽  
Yunping Dai ◽  
...  
Keyword(s):  
Zinc Finger ◽  
Zinc Finger Nucleases ◽  
Highly Efficient ◽  
Beta Lactoglobulin

scholarly journals Rapid “Open-Source” Engineering of Customized Zinc-Finger Nucleases for Highly Efficient Gene Modification

2008 ◽  
Vol 31 (2) ◽  
pp. 294-301 ◽  
Author(s):  
Morgan L. Maeder ◽  
Stacey Thibodeau-Beganny ◽  
Anna Osiak ◽  
David A. Wright ◽  
Reshma M. Anthony ◽  
...  
Keyword(s):  
Open Source ◽  
Zinc Finger ◽  
Zinc Finger Nucleases ◽  
Gene Modification ◽  
Highly Efficient ◽  
Efficient Gene

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases

2014 ◽  
Vol 32 (6) ◽  
pp. 2060-2071 ◽  
Author(s):  
Dominik Gartzke ◽  
Jürgen Delzer ◽  
Loic Laplanche ◽  
Yasuo Uchida ◽  
Yutaro Hoshi ◽  
...  
Keyword(s):  
Cell Lines ◽  
Zinc Finger ◽  
Zinc Finger Nucleases ◽  
Wild Type ◽  
P Glycoprotein
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