Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells

Yusuf B. Johari; Andrew C. Mercer; Ye Liu; Adam J. Brown; David C. James

doi:10.1002/bit.27713

Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells

Biotechnology and Bioengineering ◽

10.1002/bit.27713 ◽

2021 ◽

Vol 118 (5) ◽

pp. 2001-2015

Author(s):

Yusuf B. Johari ◽

Andrew C. Mercer ◽

Ye Liu ◽

Adam J. Brown ◽

David C. James

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Synthetic Promoters ◽

Pigment Epithelial ◽

Pigment Epithelial Cells ◽

Therapeutic Genes

A New Rapid and Non-radioactive Assay for Monitoring and Determining the Proliferation of Retinal Pigment Epithelial Cells

Korean Journal of Ophthalmology ◽

10.3341/kjo.2003.17.1.29 ◽

2003 ◽

Vol 17 (1) ◽

pp. 29 ◽

Cited By ~ 11

Author(s):

Hyeong Gon Yu ◽

Hum Chung ◽

Young Suk Yu ◽

Jong Mo Seo ◽

Jang Won Heo

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Pigment Epithelial ◽

Radioactive Assay ◽

Pigment Epithelial Cells

Nuclear Receptor Atlas of Human Retinal Pigment Epithelial Cells: Potential Relevance to Age-Related Macular Degeneration.

NURSA Datasets ◽

10.1621/datasets.06001 ◽

2013 ◽

Author(s):

MA Dwyer ◽

D Kazmin ◽

P Hu ◽

DP McDonnell ◽

G Malek

Keyword(s):

Epithelial Cells ◽

Macular Degeneration ◽

Nuclear Receptor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Age Related Macular Degeneration ◽

Pigment Epithelial ◽

Age Related ◽

Pigment Epithelial Cells

Eupatilin attenuates TGF-β2-induced proliferation and epithelial-mesenchymal transition of retinal pigment epithelial cells

Cutaneous and Ocular Toxicology ◽

10.1080/15569527.2021.1902343 ◽

2021 ◽

pp. 1-24

Author(s):

Ayca Kupeli Cinar ◽

S. Altan Ozal ◽

Riza Serttas ◽

Suat Erdogan

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Exendin-4 inhibits high glucose-induced oxidative stress in retinal pigment epithelial cells by modulating the expression and activation of p66Shc

Cutaneous and Ocular Toxicology ◽

10.1080/15569527.2020.1844727 ◽

2021 ◽

pp. 1-12

Author(s):

Nasser Al Sabaani

Keyword(s):

Oxidative Stress ◽

Epithelial Cells ◽

High Glucose ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

CD63+ extracellular vesicles from retinal pigment epithelial cells participate in crosstalk with macrophages in the innate inflammatory axis

Experimental Eye Research ◽

10.1016/j.exer.2021.108496 ◽

2021 ◽

Vol 205 ◽

pp. 108496

Author(s):

Yohei Otsuki ◽

Eiko Ito ◽

Atsushi Mukai ◽

Morio Ueno ◽

Takahiro Yamawaki ◽

...

Keyword(s):

Epithelial Cells ◽

Extracellular Vesicles ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Uptake of retinol and retinoic acid from serum retinol-binding protein by retinal pigment epithelial cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)63334-x ◽

1977 ◽

Vol 252 (15) ◽

pp. 5216-5221 ◽

Cited By ~ 2

Author(s):

C C Chen ◽

J Heller

Keyword(s):

Retinoic Acid ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Binding Protein ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Retinol Binding Protein ◽

Serum Retinol ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells

Experimental Eye Research ◽

10.1016/j.exer.2013.08.019 ◽

2013 ◽

Vol 116 ◽

pp. 151-160 ◽

Cited By ~ 18

Author(s):

Shanshan Du ◽

Shuai Wang ◽

Qiang Wu ◽

Jianyan Hu ◽

Tingting Li

Keyword(s):

Endothelial Cells ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vegf Expression ◽

Retinal Endothelial Cells ◽

Angiogenic Potential ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

J or H mtDNA haplogroups in retinal pigment epithelial cells: Effects on cell physiology, cargo in extracellular vesicles, and differential uptake of such vesicles by naïve recipient cells

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/j.bbagen.2020.129798 ◽

2020 ◽

pp. 129798

Author(s):

Crystal Nicholson ◽

Masaaki Ishii ◽

Balasubramaniam Annamalai ◽

Kyrie Chandler ◽

Marilyn Chwa ◽

...

Keyword(s):

Epithelial Cells ◽

Extracellular Vesicles ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Cell Physiology ◽

Mtdna Haplogroups ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Effects of Exogenous Extracellular Matrix Proteins on the Reattachment of Retinal Pigment Epithelial Cells

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2007.48.11.1537 ◽

2007 ◽

Vol 48 (11) ◽

pp. 1537-1547

Author(s):

Kwang Soo Kim

Keyword(s):

Extracellular Matrix ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Extracellular Matrix Proteins ◽

Retinal Pigment Epithelial Cells ◽

Matrix Proteins ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

SS‐31 protect retinal pigment epithelial cells from H 2 O 2 ‐induced cell injury by reducing apoptosis

Clinical and Experimental Pharmacology and Physiology ◽

10.1111/1440-1681.13484 ◽

2021 ◽

Author(s):

Jie Bai ◽

Yumei Yang ◽

Dingting Wu ◽

Fan Yang

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Cell Injury ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Pigment Epithelial ◽

Pigment Epithelial Cells