Compartment syndrome in experimental chronic obstructive pancreatitis: Effect of decompressing the main pancreatic duct

Background—Autosomal dominant polycystic kidney disease, the most frequent inherited polycystic disease, is a systemic disorder characterised by the development of numerous and bilateral kidney cysts leading to chronic renal failure. Extrarenal cysts are located mainly in the liver but also in various organs including the pancreas. To our knowledge, complications of pancreatic cysts in this disease have never been reported.Patient—The first case of painful chronic obstructive pancreatitis due to a true pancreatic cyst in a patient with autosomal dominant polycystic kidney disease is reported. Abdominal transparietal and endoscopic ultrasonography, computed tomography, and endoscopic retrograde cholangiopancreatography showed a cystic lesion in the body of the pancreas associated with upstream dilatation of the main pancreatic duct. Intraoperative ultrasonography before and after cyst fluid aspiration, and pancreatography and pathological examination of the resected distal pancreas confirmed that both main pancreatic duct enlargement and chronic pancreatitis were caused by a benign cyst.Conclusion—Chronic obstructive pancreatitis should be added to the extrarenal complications of autosomal dominant polycystic kidney disease.

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Compartment syndrome in experimental chronic pancreatitis: Effect of decompressing the main pancreatic duct

British Journal of Surgery ◽

10.1002/bjs.1800811049 ◽

1994 ◽

Vol 81 (10) ◽

pp. 1541-1541 ◽

Cited By ~ 1

Author(s):

T. F. Toufeeq Khan ◽

Zainal Mahmood

Keyword(s):

Chronic Pancreatitis ◽

Pancreatic Duct ◽

Compartment Syndrome ◽

Main Pancreatic Duct ◽

Experimental Chronic Pancreatitis

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Mucinous cystadenoma of pancreatic head with focal malignant alteration in a 52-year old man

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh0704204c ◽

2007 ◽

Vol 135 (3-4) ◽

pp. 204-207

Author(s):

Radoje Colovic ◽

Marjan Micev ◽

Vladimir Radak ◽

Nikica Grubor ◽

Mirjana Stojkovic ◽

...

Keyword(s):

Pancreatic Duct ◽

Mucinous Cystadenoma ◽

Pancreatic Head ◽

Postoperative Recovery ◽

The Body ◽

Chronic Obstructive ◽

Obstructive Pancreatitis ◽

Head Of The Pancreas ◽

Malignant Alteration ◽

Mucinous Cystadenomas

Mucinous cystadenomas of the pancreas are rare tumors appearing usually within the body and the tail of the pancreas in a young and middle-aged women. They rarely communicate with the pancreatic duct and occasionally may become malignant. The authors present a patient with a number of rare features. In a 52 year-old male, we did a radical pylorus-preserving cephalic duodenopancreatectomy for a mucinous cystadenoma within the head of the pancreas, which perforated into the main pancreatic duct causing chronic obstructive pancreatitis having few foci of malignant alteration. The postoperative recovery was uneventful, but three months later the patient died due to exacerbation of the underlying serious heart disease. .

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Chronic Obstructive Pancreatitis as a Delayed Complication of Pancreatic Trauma

HPB Surgery ◽

10.1155/1991/73834 ◽

1991 ◽

Vol 5 (1) ◽

pp. 49-60 ◽

Cited By ~ 18

Author(s):

Edward L. Bradley

Keyword(s):

Chronic Pancreatitis ◽

Pancreatic Duct ◽

Motor Vehicle ◽

Chronic Obstructive ◽

Pancreatic Trauma ◽

Vehicle Accidents ◽

Obstructive Pancreatitis ◽

Delayed Complication ◽

Pancreatic Duct Hypertension ◽

Societal Violence

Increasing surgical experience with the immediate consequences of pancreatic injuries has resulted from parallel growth in the volume of motor vehicle accidents and societal violence. However, few surgeons are aware that complications may be considerably delayed following pancreatic trauma, occurring in some cases months to years after apparent recovery from the original injury. In four patients with blunt pancreatic trauma initially treated by non-operative means, stricture of the main pancreatic duct developed over a period of months as a result of progressive fibrosis at the site of ductal injury. Pancreatic duct hypertension was demonstrated to be present in the obstructed duct, and secondary changes of chronic pancreatitis developed in the obstructed segment of the gland (“upstream” chronic pancreatitis). Seven similar patients with delayed onset of chronic obstructive pancreatitis after pancreatic trauma were found in the literature. Symptoms related to these acquired ductal strictures are most commonly those of abdominal pain and recurrent episodes of acute pancreatitis. Recognition of post-traumatic chronic obstructive pancreatitis principally involves awareness that injuries to the pancreatic duct can produce remote complications. Pancreatoenteric drainage, or resection of the obstructed segment of pancreas, provides prompt and effective relief.

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