scholarly journals Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in chinese hamster ovary cells

2012 ◽  
Vol 28 (3) ◽  
pp. 846-855 ◽  
Author(s):  
Megan Mason ◽  
Bernadette Sweeney ◽  
Katharine Cain ◽  
Paul Stephens ◽  
Susan T. Sharfstein
Keyword(s):  
Monoclonal Antibody ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Sequence Variants ◽  
Ovary Cells ◽  
Recombinant Monoclonal Antibody ◽  
Stable Production ◽  
Antibody Sequence

scholarly journals Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System

10.3791/58947 ◽  
2019 ◽  
Author(s):  
Sai Rashmika Velugula-Yellela ◽  
David N. Powers ◽  
Phillip Angart ◽  
Anneliese Faustino ◽  
Talia Faison ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells

Efficient enrichment of high-producing recombinant Chinese hamster ovary cells for monoclonal antibody by flow cytometry

2015 ◽  
Vol 120 (3) ◽  
pp. 340-346 ◽  
Author(s):  
Takeshi Okumura ◽  
Kenji Masuda ◽  
Kazuhiko Watanabe ◽  
Kenji Miyadai ◽  
Koichi Nonaka ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Flow Cytometry ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells

LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells

2012 ◽  
Vol 109 (12) ◽  
pp. 3103-3111 ◽  
Author(s):  
William Pooi Kat Chong ◽  
Shu Hui Thng ◽  
Ai Ping Hiu ◽  
Dong-Yup Lee ◽  
Eric Chun Yong Chan ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells
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