Chromatography process development in the quality by design paradigm I: Establishing a high-throughput process development platform as a tool for estimating “characterization space” for an ion exchange chromatography step

2013 ◽  
Vol 29 (2) ◽  
pp. 403-414 ◽  
Author(s):  
R. Bhambure ◽  
A. S. Rathore
Keyword(s):  
Ion Exchange ◽  
High Throughput ◽  
Quality By Design ◽  
Process Development ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Development Platform ◽  
Design Paradigm ◽  
Chromatography Step

Strategic assay deployment as a method for countering analytical bottlenecks in high throughput process development: Case studies in ion exchange chromatography

2012 ◽  
Vol 28 (5) ◽  
pp. 1292-1302 ◽  
Author(s):  
Spyridon Konstantinidis ◽  
Eva Heldin ◽  
Sunil Chhatre ◽  
Ajoy Velayudhan ◽  
Nigel Titchener-Hooker
Keyword(s):  
Ion Exchange ◽  
Case Studies ◽  
High Throughput ◽  
Process Development ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography

scholarly journals High throughput process development for the purification of rapeseed proteins napin and cruciferin by ion exchange chromatography

2021 ◽  
Vol 125 ◽  
pp. 228-241
Author(s):  
Mónica Moreno-González ◽  
Pattra Chuekitkumchorn ◽  
Marcelo Silva ◽  
Roos Groenewoud ◽  
Marcel Ottens
Keyword(s):  
Ion Exchange ◽  
High Throughput ◽  
Process Development ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Rapeseed Proteins

Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step

2011 ◽  
Vol 35 (1) ◽  
pp. 183-190 ◽  
Author(s):  
K. Westerberg ◽  
E. Broberg Hansen ◽  
M. Degerman ◽  
T. Budde Hansen ◽  
B. Nilsson
Keyword(s):  
Ion Exchange ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Model Based ◽  
Chromatography Step

Micro-Plate Based Monolithic Ion-Exchange Chromatography for High Throughput Protein Purification Process Design

2008 ◽  
Vol 41 (3) ◽  
pp. 200-205 ◽  
Author(s):  
Noriko Yoshimoto ◽  
Yuko Nishijima ◽  
Parvin Akbarzadehlaleh ◽  
Sachie Fujii ◽  
Mitsuyo Abe ◽  
...  
Keyword(s):  
Ion Exchange ◽  
Protein Purification ◽  
High Throughput ◽  
Process Design ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Purification Process

Using computer simulation to assist in the robustness analysis of an ion-exchange chromatography step

2005 ◽  
Vol 1063 (1-2) ◽  
pp. 99-109 ◽  
Author(s):  
Niklas Jakobsson ◽  
David Karlsson ◽  
Jan Peter Axelsson ◽  
Guido Zacchi ◽  
Bernt Nilsson
Keyword(s):  
Computer Simulation ◽  
Ion Exchange ◽  
Robustness Analysis ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Chromatography Step

Hydrophilic modification gigaporous resins with poly(ethylenimine) for high-throughput proteins ion-exchange chromatography

2014 ◽  
Vol 1343 ◽  
pp. 109-118 ◽  
Author(s):  
Rongyue Zhang ◽  
Qiang Li ◽  
Yang Gao ◽  
Juan Li ◽  
Yongdong Huang ◽  
...  
Keyword(s):  
Ion Exchange ◽  
High Throughput ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Hydrophilic Modification

Model based robustness analysis of an ion-exchange chromatography step

2007 ◽  
Vol 1138 (1-2) ◽  
pp. 109-119 ◽  
Author(s):  
Niklas Jakobsson ◽  
Marcus Degerman ◽  
Emelie Stenborg ◽  
Bernt Nilsson
Keyword(s):  
Ion Exchange ◽  
Robustness Analysis ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Model Based ◽  
Chromatography Step

Analytical characterization of complex, biotechnological feedstocks by pH gradient ion exchange chromatography for purification process development

2013 ◽  
Vol 1311 ◽  
pp. 55-64 ◽  
Author(s):  
Frieder Kröner ◽  
Alexander T. Hanke ◽  
Beckley K. Nfor ◽  
Martijn W.H. Pinkse ◽  
Peter D.E.M. Verhaert ◽  
...  
Keyword(s):  
Ion Exchange ◽  
Process Development ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Ph Gradient ◽  
Purification Process ◽  
Analytical Characterization
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