Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients

Cancer Medicine ◽

10.1002/cam4.1372 ◽

2018 ◽

Vol 7 (3) ◽

pp. 746-756 ◽

Author(s):

Ari Vanderwalde ◽

David Spetzler ◽

Nianqing Xiao ◽

Zoran Gatalica ◽

John Marshall

Keyword(s):

Next Generation Sequencing ◽

Microsatellite Instability ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Tumor Mutational Burden Calculation and Microsatellite Instability Detection in Clinical Next-Generation Sequencing Assays

Advances in Molecular Pathology ◽

10.1016/j.yamp.2021.07.008 ◽

2021 ◽

Vol 4 ◽

pp. 199-204

Author(s):

Ashkan Bigdeli ◽

Amanda Oran ◽

Robyn Sussman

Keyword(s):

Next Generation Sequencing ◽

Microsatellite Instability ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Abstract 5706: A blood-based next-generation sequencing assay to determine tumor mutational burden (bTMB) is associated with benefit to an anti-PD-L1 inhibitor, atezolizumab

10.1158/1538-7445.am2018-5706 ◽

2018 ◽

Author(s):

David Fabrizio ◽

Daniel Lieber ◽

Christine Malboeuf ◽

Jacob Silterra ◽

Emily White ◽

...

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Abstract A41: Analytic validation and clinical feasibility of a next-generation sequencing assay to assess tumor mutational burden from blood (bTMB) as a biomarker for anti-PD-L1 response in NSCLC

10.1158/2326-6074.tumimm17-a41 ◽

2018 ◽

Author(s):

Daniel S. Lieber ◽

Emily White ◽

Jacob Silterra ◽

Shan Zhong ◽

Tina Brennan ◽

...

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Comparison of three different gene panels for determination of tumor mutational burden by next generation sequencing

Annals of Oncology ◽

10.1093/annonc/mdz073.006 ◽

2019 ◽

Vol 30 ◽

pp. ii9

Author(s):

R. Pappesch ◽

C. Heydt ◽

J. Rehker ◽

S. Merkelbach-Bruse

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Gene Panels ◽

Generation Sequencing

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Association Between Preanalytical Factors and Tumor Mutational Burden Estimated by Next‐Generation Sequencing‐Based Multiplex Gene Panel Assay

The Oncologist ◽

10.1634/theoncologist.2018-0587 ◽

2019 ◽

Vol 24 (12) ◽

Author(s):

Pham Nguyen Quy ◽

Masashi Kanai ◽

Keita Fukuyama ◽

Tadayuki Kou ◽

Tomohiro Kondo ◽

...

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Use of Tumor-Only Next Generation Sequencing to Identify Clinicopathologic and Genomic Correlates of Tumor Mutational Burden and Immunotherapy Response in Non-Small Cell Lung Cancer

SSRN Electronic Journal ◽

10.2139/ssrn.3247896 ◽

2018 ◽

Author(s):

Mark Awad ◽

Navin R. Mahadevan ◽

Andrew Polio ◽

Elizabeth Jimenez Aguilar ◽

Natalie I Vokes ◽

...

Keyword(s):

Lung Cancer ◽

Next Generation Sequencing ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Next Generation ◽

Small Cell Lung ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Abstract 1255: Identification of mutational landscape predicting efficacy of immune checkpoint blockades and recurrent mutations related to high tumor mutational burden in hepatocellular carcinoma by next generation sequencing

10.1158/1538-7445.am2019-1255 ◽

2019 ◽

Author(s):

Li Li ◽

Zhaohong Wen ◽

Michael J. Overman ◽

Xiaosong Rao ◽

Yuting Yi ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Next Generation Sequencing ◽

Immune Checkpoint ◽

Next Generation ◽

Mutational Landscape ◽

Mutational Burden ◽

Recurrent Mutations ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Development and analytical validation of a plasma-based tumor mutational burden (TMB) score from next-generation sequencing panels

Annals of Oncology ◽

10.1093/annonc/mdy269.129 ◽

2018 ◽

Vol 29 ◽

pp. viii41 ◽

Author(s):

K. Quinn ◽

E. Helman ◽

T. Nance ◽

C. Artieri ◽

J. Yen ◽

...

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Analytical Validation ◽

Mutational Burden ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Pan-cancer Analysis of Tumor Mutational Burden and Homologous Recombination DNA Damage Repair Using Targeted Next-Generation Sequencing

Cancer Research and Treatment ◽

10.4143/crt.2020.798 ◽

2021 ◽

Author(s):

Hai-Yun Wang ◽

Ling Deng ◽

Ying-Qing Li ◽

Xiao Zhang ◽

Ya-Kang Long ◽

...

Keyword(s):

Next Generation Sequencing ◽

Homologous Recombination ◽

Next Generation ◽

Targeted Next Generation Sequencing ◽

Mutational Burden ◽

Damage Repair ◽

Tumor Mutational Burden ◽

Generation Sequencing

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Abstract 5132: Assessing tumor mutational burden and profiling variants from FFPE samples using a PCR-based next-generation sequencing assay

10.1158/1538-7445.am2019-5132 ◽

2019 ◽

Author(s):

Ruchi Chaudhary ◽

Charles Scafe ◽

Dinesh Cyanam ◽

Vinay Mittal ◽

Warren Tom ◽

...

Keyword(s):

Next Generation Sequencing ◽

Next Generation ◽

Mutational Burden ◽

Ffpe Samples ◽

Tumor Mutational Burden ◽

Generation Sequencing

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