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Tumor Mutational Burden Calculation and Microsatellite Instability Detection in Clinical Next-Generation Sequencing Assays
Advances in Molecular Pathology
◽
10.1016/j.yamp.2021.07.008
◽
2021
◽
Vol 4
◽
pp. 199-204
Author(s):
Ashkan Bigdeli
◽
Amanda Oran
◽
Robyn Sussman
Keyword(s):
Next Generation Sequencing
◽
Microsatellite Instability
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
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References
Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients
Cancer Medicine
◽
10.1002/cam4.1372
◽
2018
◽
Vol 7
(3)
◽
pp. 746-756
◽
Cited By ~ 121
Author(s):
Ari Vanderwalde
◽
David Spetzler
◽
Nianqing Xiao
◽
Zoran Gatalica
◽
John Marshall
Keyword(s):
Next Generation Sequencing
◽
Microsatellite Instability
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Abstract 5706: A blood-based next-generation sequencing assay to determine tumor mutational burden (bTMB) is associated with benefit to an anti-PD-L1 inhibitor, atezolizumab
10.1158/1538-7445.am2018-5706
◽
2018
◽
Cited By ~ 9
Author(s):
David Fabrizio
◽
Daniel Lieber
◽
Christine Malboeuf
◽
Jacob Silterra
◽
Emily White
◽
...
Keyword(s):
Next Generation Sequencing
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Abstract A41: Analytic validation and clinical feasibility of a next-generation sequencing assay to assess tumor mutational burden from blood (bTMB) as a biomarker for anti-PD-L1 response in NSCLC
10.1158/2326-6074.tumimm17-a41
◽
2018
◽
Author(s):
Daniel S. Lieber
◽
Emily White
◽
Jacob Silterra
◽
Shan Zhong
◽
Tina Brennan
◽
...
Keyword(s):
Next Generation Sequencing
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Comparison of three different gene panels for determination of tumor mutational burden by next generation sequencing
Annals of Oncology
◽
10.1093/annonc/mdz073.006
◽
2019
◽
Vol 30
◽
pp. ii9
Author(s):
R. Pappesch
◽
C. Heydt
◽
J. Rehker
◽
S. Merkelbach-Bruse
Keyword(s):
Next Generation Sequencing
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Gene Panels
◽
Generation Sequencing
Download Full-text
Association Between Preanalytical Factors and Tumor Mutational Burden Estimated by Next‐Generation Sequencing‐Based Multiplex Gene Panel Assay
The Oncologist
◽
10.1634/theoncologist.2018-0587
◽
2019
◽
Vol 24
(12)
◽
Cited By ~ 1
Author(s):
Pham Nguyen Quy
◽
Masashi Kanai
◽
Keita Fukuyama
◽
Tadayuki Kou
◽
Tomohiro Kondo
◽
...
Keyword(s):
Next Generation Sequencing
◽
Gene Panel
◽
Next Generation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Use of Tumor-Only Next Generation Sequencing to Identify Clinicopathologic and Genomic Correlates of Tumor Mutational Burden and Immunotherapy Response in Non-Small Cell Lung Cancer
SSRN Electronic Journal
◽
10.2139/ssrn.3247896
◽
2018
◽
Author(s):
Mark Awad
◽
Navin R. Mahadevan
◽
Andrew Polio
◽
Elizabeth Jimenez Aguilar
◽
Natalie I Vokes
◽
...
Keyword(s):
Lung Cancer
◽
Next Generation Sequencing
◽
Small Cell Lung Cancer
◽
Cell Lung Cancer
◽
Small Cell
◽
Next Generation
◽
Small Cell Lung
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Abstract 1255: Identification of mutational landscape predicting efficacy of immune checkpoint blockades and recurrent mutations related to high tumor mutational burden in hepatocellular carcinoma by next generation sequencing
10.1158/1538-7445.am2019-1255
◽
2019
◽
Author(s):
Li Li
◽
Zhaohong Wen
◽
Michael J. Overman
◽
Xiaosong Rao
◽
Yuting Yi
◽
...
Keyword(s):
Hepatocellular Carcinoma
◽
Next Generation Sequencing
◽
Immune Checkpoint
◽
Next Generation
◽
Mutational Landscape
◽
Mutational Burden
◽
Recurrent Mutations
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Development and analytical validation of a plasma-based tumor mutational burden (TMB) score from next-generation sequencing panels
Annals of Oncology
◽
10.1093/annonc/mdy269.129
◽
2018
◽
Vol 29
◽
pp. viii41
◽
Cited By ~ 5
Author(s):
K. Quinn
◽
E. Helman
◽
T. Nance
◽
C. Artieri
◽
J. Yen
◽
...
Keyword(s):
Next Generation Sequencing
◽
Next Generation
◽
Analytical Validation
◽
Mutational Burden
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
Pan-cancer Analysis of Tumor Mutational Burden and Homologous Recombination DNA Damage Repair Using Targeted Next-Generation Sequencing
Cancer Research and Treatment
◽
10.4143/crt.2020.798
◽
2021
◽
Author(s):
Hai-Yun Wang
◽
Ling Deng
◽
Ying-Qing Li
◽
Xiao Zhang
◽
Ya-Kang Long
◽
...
Keyword(s):
Dna Damage
◽
Next Generation Sequencing
◽
Homologous Recombination
◽
Next Generation
◽
Targeted Next Generation Sequencing
◽
Mutational Burden
◽
Damage Repair
◽
Tumor Mutational Burden
◽
Pan Cancer
◽
Generation Sequencing
Download Full-text
Abstract 5132: Assessing tumor mutational burden and profiling variants from FFPE samples using a PCR-based next-generation sequencing assay
10.1158/1538-7445.am2019-5132
◽
2019
◽
Author(s):
Ruchi Chaudhary
◽
Charles Scafe
◽
Dinesh Cyanam
◽
Vinay Mittal
◽
Warren Tom
◽
...
Keyword(s):
Next Generation Sequencing
◽
Next Generation
◽
Mutational Burden
◽
Ffpe Samples
◽
Tumor Mutational Burden
◽
Generation Sequencing
Download Full-text
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