scholarly journals IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution

2020 ◽  
Vol 9 (12) ◽  
pp. 4386-4394
Author(s):  
Erika F. Rodriguez ◽  
Federico De Marchi ◽  
Parvez M. Lokhandwala ◽  
Deborah Belchis ◽  
Rena Xian ◽  
...  
2020 ◽  
Author(s):  
Shahan Mamoor

Non-small cell lung adenocarcinoma (NSCLC) is a leading cause of death in the United States and worldwide (1, 2). We mined published microarray data (3, 4, 5) to discover genes associated with NSCLC. We identified significant differential expression of the tyrosine kinase TEK in tumors from patients with NSCLC. TEK may be of relevance to the initiation, progression or maintenance of non-small cell lung cancers.


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