Synthesis and evaluation of novel quinazolinone derivatives as potential anti‐HCC agents

2021 ◽  
Author(s):  
Jingying Qiu ◽  
Yueting Zou ◽  
Qingchuan Liu ◽  
Chunyu Jiang ◽  
Qingqing Zhou ◽  
...  
Keyword(s):  
Quinazolinone Derivatives

Design and Synthesis of Quinazolinone Derivatives as Anti-inflammatory Agents: Pharmacophore Modeling and 3D QSAR Studies

2014 ◽  
Vol 10 (7) ◽  
pp. 711-723 ◽  
Author(s):  
P. Chaitanya ◽  
G. Reddy ◽  
G. Varun ◽  
L.M. Srikanth ◽  
V.V.S.R. Prasad ◽  
...  
Keyword(s):  
3D Qsar ◽  
Pharmacophore Modeling ◽  
Qsar Studies ◽  
Design And Synthesis ◽  
Anti Inflammatory ◽  
Quinazolinone Derivatives

Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents

2013 ◽  
Vol 22 (12) ◽  
pp. 5823-5831 ◽  
Author(s):  
Mohamed F. Zayed ◽  
Hany E. A. Ahmed ◽  
Abdel-Sattar M. Omar ◽  
Adel S. Abdelrahim ◽  
Khaled El-Adl
Keyword(s):  
Evaluation Studies ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Anticonvulsant Agents ◽  
Quinazolinone Derivatives ◽  
Synthesis And Biological Evaluation

Synthesis, characterization, and evaluation of some novel 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents

2012 ◽  
Vol 22 (1) ◽  
pp. 440-452 ◽  
Author(s):  
Awatef A. Farag ◽  
Ebtsam M. Khalifa ◽  
Naima A. Sadik ◽  
Samir Y. Abbas ◽  
Abdullah G. Al-Sehemi ◽  
...  
Keyword(s):  
Analgesic Agents ◽  
Anti Inflammatory ◽  
Quinazolinone Derivatives

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists

2008 ◽  
Vol 18 (23) ◽  
pp. 6041-6045 ◽  
Author(s):  
Takashi Mizutani ◽  
Tsuyoshi Nagase ◽  
Sayaka Ito ◽  
Yasuhisa Miyamoto ◽  
Takeshi Tanaka ◽  
...  
Keyword(s):  
Histamine H3 Receptor ◽  
Inverse Agonists ◽  
H3 Receptor ◽  
Quinazolinone Derivatives ◽  
Histamine H3

Quinazolinone Derivatives of Biological Interest V. Novel 4(3H)-Quinazolinones with Sedative-Hypnotic, Anticonvulsant and Antiinflammatory Activities

1993 ◽  
Vol 58 (8) ◽  
pp. 1963-1968 ◽  
Author(s):  
Abdel-Alim M. Abdel-Alim ◽  
Abdel-Nasser A. El-Shorbagi ◽  
Mahmoud A. El-Gendy ◽  
Hosny A. H. El-Shareif
Keyword(s):  
Present Communication ◽  
Biological Interest ◽  
Quinazoline Derivatives ◽  
Quinazolinone Derivatives ◽  
Derivatives Of

2-Methyl-4(3H)-quinazolines carrying alkyl, cycloalkyl, aralkyl or aryl substituents at N-3 of the quinazoline ring exhibit analgetic, antipyretic and antiinflammatory activities comparable to those of aspirin and phenylbutazone. In our previous work, various 4(3H)-quinazoline derivatives were prepared. The present communication is a continuation of our effort in this field.

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