Acute thyroid swelling with severe hypothyroid myxoedema after COVID‐19 vaccination

Branchial pouch-derived anomalies may arise from remnants of the first, second, or third/fourth branchial arches. Branchial pouch-related structures are found within the thyroid gland in the form of solid cell rests, epithelial lined cyst with or without an associated lymphoid component, thymic and/or parathyroid tissue, and less commonly in the form of heterotopic cartilage. We present a rare case of left solid thyroid swelling nearby two cervical nodules in a seven-year-old female with a clinical diagnosis suggestive of malignant thyroid tumor with metastasis to the cervical lymph nodes. Histopathological examination revealed that it was compatible with third/fourth branchial pouch-derived anomaly composed of mature cartilage and thymic and parathyroid tissues for clinical and radiological correlations.

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Our experience of clinico-pathological study of thyroid swelling

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20183396 ◽

2018 ◽

Vol 4 (5) ◽

pp. 1156

Author(s):

Vilas R. Kirdak ◽

Sambhaji G. Chintale ◽

Sonali P. Jatale ◽

Kaleem A. Shaikh

Keyword(s):

Cost Effective ◽

Safe Procedure ◽

Chi Square ◽

Radiological Investigation ◽

Statistical Tool ◽

Fourth Decade ◽

Chi Square Test ◽

The Common ◽

Thyroid Swelling ◽

High Index Of Suspicion

Background: Diseases of thyroid gland are extremely common. Majority of palpable thyroid swellings are asymptomatic occurs in 5% of the population. The main objective of present study is to know the accuracy of FNAC in preoperative diagnosis of clinically palpable thyroid swelling and evaluate the efficiency of FNAC, USG, and TFT in differentiating between benign and malignant thyroid swelling and their confirmation by histopathological reports after operation.Methods: This prospective study is carried out in 120 cases of thyroid swelling attending to the ENT opd at our hospital. Pearson chi square test used as statistical tool to analyse the data. All patients informed written consent taken. The patients are subjected to detailed history with thorough clinical examination, pathological and radiological investigation. FNAC, USG and TFT were done in each case. The result of FNAC was interpreted. Results: The present study includes 120 cases. All patient examined clinically, pathologically and radiological. The common age group of presentation of thyroid swelling is between second to fourth decade. Youngest patient is of 15 yrs. old and oldest is being 68 yrs of age. All 120 cases were evaluated preoperatively and provisional diagnosis was made on the basis of FNAC, TFT and USG. 111 Cases were operated out of total 120 cases. So, the overall accuracy of FNAC in comparisons to HPR is 99.15% with no false positive reports.Conclusions: The overall incidence of the malignancy in thyroid swelling varies from 10% to 30% according to various studies, in our study the overall incidence of malignancy in thyroid swelling was 5.8%. High index of suspicion should be kept in mind during physical examination for detection of malignancy. FNAC should be done in all cases preoperatively FNAC is safe procedure and cost effective.

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Clinicopathological study of thyroid swellings

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20201533 ◽

2020 ◽

Vol 6 (5) ◽

pp. 974

Author(s):

Anchal Gupta ◽

Padam Singh Jamwal

Keyword(s):

Fine Needle Aspiration ◽

Histopathological Examination ◽

Clinical Problem ◽

Neck Surgery ◽

Needle Aspiration ◽

Functional Abnormality ◽

Fine Needle ◽

Common Diagnosis ◽

Thyroid Swelling ◽

Needle Aspiration Cytology

Background: Diseases of the thyroid continue to be a common clinical problem having a prevalence rate of 4 to 7% in the general population.Methods: This retrospective study was conducted in the Department of ENT, Head and Neck Surgery, SMGS Hospital, Jammu from January 2018 to January 2020. A thorough history taking, meticulous clinical examination, routine hematological and biochemical investigations were done in all the patients. General examination of the patient was done and looked for thyroid functional abnormality followed by local examination was carried out to locate and identify the site of the swelling, shape, size and consistency of the thyroid swelling and clinical diagnosis was made. All thyroid swelling cases were subjected to fine needle aspiration cytology (FNAC). The type of thyroidectomy is based on the size and type of thyroid whether neoplastic or non-neoplastic. All the specimens were sent for histopathological examination. Results: Out of 60 patients in the study, 56 were females and only 4 were males. The most common age group was 31 to 40 years seen in 24 (40%) patients. The most common presenting symptom was swelling in the neck seen in 58 (96.67%) patients. The most common diagnosis on FNAC was colloid goiter seen in 40 (66.67%) patients. The most common was benign nodular colloid goiter seen in 35 (58.33%) patients.Conclusions: Fine needle aspiration is a very useful and indispensible test in the diagnosis of thyroid lesions.

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Clinicopathological study of thyroid swelling and its management

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20201290 ◽

2020 ◽

Vol 6 (4) ◽

pp. 727

Author(s):

Seema Patel ◽

Varsha J. Gattani ◽

Ashok Z. Nitnaware

Keyword(s):

Papillary Carcinoma ◽

Surgical Management ◽

False Negative ◽

Malignant Lesion ◽

Nodular Goiter ◽

Follicular Neoplasm ◽

Histopathological Diagnosis ◽

Predictive Values ◽

Neoplastic Lesion ◽

Thyroid Swelling

Background: There is high prevalence of thyroid lesions in India. In this study, an attempt is made to find out the clinical spectrum of thyroid swellings in central India, diagnostic accuracy of fine needle aspiration cytology (FNAC), appropriate surgical management and to compare it with postoperative histopathological diagnosis so as to determine its role in surgical management.Methods: In this prospective study, 100 subjects presenting to ENT OPD of GMC, Nagpur during the period from September 2017 to August 2019 with thyroid swelling who were fit to undergo surgery and willing to participate in the study were selected. After detailed evaluation and routine investigations, thyroid function test (TFT), FNAC, ultrasonography (USG) neck, all the subjects underwent required thyroidectomy. The postoperative histopathological examination (HPE) report was correlated with cytological report. Results: In 100 subjects, majority of subjects were from 4th decade (32%) with female: male ratio=6.14:1. FNAC findings were colloid goiter (61%), nodular goiter (19%), follicular neoplasm (10%), and papillary carcinoma (9%). On HPE, colloid goitre (57%) was most common non-neoplastic lesion and papillary carcinoma (65.21 %) was most common malignant lesion. Hemithyroidectomy (70%) was most common procedure done. Transient hypocalcemia (5%), recurrent laryngeal nerve (RLN) paresis (2%) were the postoperative complications encountered. Sensitivity, specificity, accuracy, positive and negative predictive values of FNAC to diagnose malignancy were 55.6%, 100%, 91%, 100% and 90% respectively.Conclusions: FNAC is an easy, rapid, reliable, cost-effective, minimally invasive and readily repeatable technique for diagnosis of thyroid swellings. The common false negative diagnosis is seen in follicular pattern cases, cystic papillary thyroid carcinoma (PTC) and papillary microcarcinoma.

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