scholarly journals Our experience of clinico-pathological study of thyroid swelling

Author(s):  
Vilas R. Kirdak ◽  
Sambhaji G. Chintale ◽  
Sonali P. Jatale ◽  
Kaleem A. Shaikh

<p class="abstract"><strong>Background:</strong> Diseases of thyroid gland are extremely common. Majority of palpable thyroid swellings are asymptomatic occurs in 5% of the population. The main objective of present study is to know the accuracy of FNAC in preoperative diagnosis of clinically palpable thyroid swelling and evaluate the efficiency of FNAC, USG, and TFT in differentiating between benign and malignant thyroid swelling and their confirmation by histopathological reports after operation.</p><p class="abstract"><strong>Methods:</strong> This prospective study is carried out in 120 cases of thyroid swelling attending to the ENT opd at our hospital. Pearson chi square test used as statistical tool to analyse the data. All patients informed written consent taken. The patients are subjected to detailed history with thorough clinical examination, pathological and radiological investigation. FNAC, USG and TFT were done in each case. The result of FNAC was interpreted.  </p><p class="abstract"><strong>Results:</strong> The present study includes 120 cases. All patient examined clinically, pathologically and radiological. The common age group of presentation of thyroid swelling is between second to fourth decade. Youngest patient is of 15 yrs. old and oldest is being 68 yrs of age. All 120 cases were evaluated preoperatively and provisional diagnosis was made on the basis of FNAC, TFT and USG. 111 Cases were operated out of total 120 cases. So, the overall accuracy of FNAC in comparisons to HPR is 99.15% with no false positive reports.</p><p class="abstract"><strong>Conclusions:</strong> The overall incidence of the malignancy in thyroid swelling varies from 10% to 30% according to various studies, in our study the overall incidence of malignancy in thyroid swelling was 5.8%. High index of suspicion should be kept in mind during physical examination for detection of malignancy. FNAC should be done in all cases preoperatively FNAC is safe procedure and cost effective.</p><p> </p>

Author(s):  
Armel Arputha Sivarajan ◽  
Raju MVS ◽  
B. Padhmini ◽  
R.S. Jenish

Background: Ultrasonography (USG) of abdomen remains one of the commonly asked investigations by the surgeon in patients with suspected acute abdomen. The advantage of USG over other radiological investigation is that it is easily available, cost effective, portable, no known side effects, non-invasive and requires minimal patient preparation for carrying out the examination. The present study aimed at evaluating ultrasonography findings of appendicitis and to correlate with operative and histo-pathological findings. Material and Methods: In our study, USG evaluation was done by the investigators for 61 clinically diagnosed patients, so as to achieve 50 radiologically confirmed appendicitis cases which was the required sample. The study was carried out from December 2013 to September 2015. Data was analysed using the statistical software SPSS version 21.0. Chi Square test was applied to test statistically significant difference in proportion. Results: In the present study the mean age the study participants was 26.42 years. Majority of the study participants were males 29 (58%) while females represented 42%.The average size of the appendix among the study participants was observed to be 7.08 mm with a standard deviation of ± 1.07 mm. Among all the study participants with acute appendicitis in our study 22% of the patients had perforation of appendix. In our study, we proved that all USG diagnosed appendicitis cases (100%) were histo-pathologically correct but the variations found in diagnosing the perforation status. We found that the USG had 73.33% and 100% sensitivity and specificity in finding the perforation status.


2021 ◽  
pp. 63-66
Author(s):  
Wasif Mohammad Ali ◽  
Nazia Nanen ◽  
Atia Zaka Ur Rab ◽  
Syed Amjad Ali Rizvi ◽  
Mehtab Ahmad

Introduction: Laparoscopic cholecystectomy has become procedure of choice for treatment of symptomatic gallstone [1] disease . Even though it is a safe procedure occasionally it can be difcult and requires conversion to open cholecystectomy for various problems faced during surgery. Preoperative prediction of difcult laparoscopic cholecystectomy and likelihood of conversion to open cholecystectomy will avoid such complications and overall cost of treatment. Aim: To evaluate the clinico-radiological factors predicting difcult laparoscopic cholecystectomy Methods: This was a prospective study conducted from October 2018 to November 2020. Total of 101 patients meeting inclusion criteria undergoing laparoscopic cholecystectomy were included in the study. Various clinical, radiological and biochemical parameters and intraoperative difculties during surgery were recorded. The statistical analysis was done using chi-square test and ANOVA test. Results: The parameters such as sex, age, duration of disease, co-morbid disease, previous history of cholecystitis, palpable gall bladder, BMI, TLC, thickness of gall bladder, largest stone size and impacted stone are found statistically signicant in predicting difcult laparoscopic cholecystectomy and conversion to open cholecystectomy preoperatively. Conclusion: Difcult laparoscopic cholecystectomy may be predicted preoperatively even with a good clinical judgement whereas both clinical and radiological parameters provide a better preoperative prediction of difcult cholecystectomy so that the surgeon can prepared in advance for the complications.


2021 ◽  
Vol 10 (2) ◽  
pp. 104-113
Author(s):  
Md Benzamin ◽  
Md Rukunuzzaman ◽  
Md Wahiduzzaman Mazumder ◽  
ASM Bazlul Karim

Hirschsprung’s disease (HD) is a rare genetic congenital defect of intestine causing failure of migration of parasympathetic ganglionic cells in some definite part of intestine, resulting in functional intestinal obstruction. It commonly involves rectosigmoid region of colon but other parts of colon or total colon, even small intestine may be affected. Incidence is 1/5000 live births. It is one of the common pediatric surgical problems and 2nd most organic cause of constipation. Symptoms may be evident from 1st day of life. About 90% infants with Hirschprung’s disease fail to pass meconium in 1st 24 hours of life. About 80% HD cases are diagnosed in early few months of life and present with abdominal distention, constipation, poor feeding, vomiting etc. HD enterocolitis is a devastating condition related to mortality. HD may be associated with some congenital anomalies and syndrome. High index of suspicion is the main key to diagnosis. Radiological investigation supports the diagnosis and rectal biopsy for histopathology is confirmatory. Although it is a surgical problem, physician can play a key role in early diagnosis and thus help to prevent HD enterocolitis-related mortality and restore near-normal life. J Enam Med Col 2020; 10(2): 104-113


2021 ◽  
Vol 11 (5) ◽  
pp. 74-81
Author(s):  
Ayushi Rajkumar Jain ◽  
Doss Prakash ◽  
Sheetal Swamy

The alarming statistics of COVID-19 surges up in 2021 throwing an enormous burden on the healthcare system across the world. According to WHO reports on 14th April 2021, globally 136,996,364 confirmed COVID-19 cases are reported across the continents, including 2,951,832 deaths. The state of Maharashtra reported the maximum number of cases of India including high mortality rate. This study was conducted to identify and describe the relation of different predictors (Age, gender, duration of hospital stay, presence of co morbidities) of mortality among the COVID-19 deceased patients by retrospectively analyzing the medical case records of 121 patients from a dedicated COVID hospital at Aurangabad from July 2020 to December 2020. Chi-square test was performed to assess the association between causes of death with different cluster of variables and their significance. This study helps us to identify risk factors that show association between various predictors and mortality rate in COVID-19 patients. Out of 121 deaths, 96 (79%) were male, 61 (49.6%) were in age group between 60-79 years, ARDS was one of the major complication in the deceased patients accounting 29.8% and cardio respiratory arrest was the common cause of death among the deceased patients with 85%. It was also observed that mortality rate was very higher in the initial five days of hospitalization with critical care support. Our result findings provide clinical inferences for physicians to identify high-risk factors with COVID-19 at a very early stage. Key words: COVID-19, Mortality rate, Demographic predictors, Co-morbidities, Cardio respiratory arrest.


2021 ◽  
Vol 32 (3) ◽  
Author(s):  
Mahlodi Esther Masekela ◽  
Khomotso Semenya

Despite improved electrification rates and several government policies introduced to encourage rural households to switch from traditional to modern fuels, most South African households still rely on firewood for their energy needs. This study sought to assess the factors that influence the use of firewood in Ga-Malahlela village in the Limpopo province. To this end, a structured questionnaire was administered to 67 households. Microsoft Excel and the Statistical Package for Social Sciences were used to code and log in the data. The chi-square test was used to determine the relationship between the choice of energy source(s) and socio-economic factors. It was established that firewood was still widely used: by 61% of the participants for cooking, by 64% for space heating, and by 46% for water heating. For lighting, electricity was used by 98.5% of the participants, while liquefied petroleum gas was used by 1.5%. The dependency on firewood was mainly due to the socio-economic status of the surveyed households, which included income, education level, household size, and preference. Rural firewood reliance continues, due to socio-economic factors such as indigence, preference, and the inaccessibility of services like free basic electricity. It is therefore recommended that the Polokwane Local Municipality should play a part in assisting poor communities with cleaner, cost-effective fuel alternatives such as solar energy, biogas, and liquefied petroleum gas.


Author(s):  
Chinmay N. Gokhale ◽  
Smita S. Chavhan ◽  
Balkrishna B. Adsul ◽  
Maharudra A. Kumbhar ◽  
Kirti V. Kinge ◽  
...  

Background: India was one of the leaders in terms of COVID-19 cases across year 2020. Hypothyroidism is one of the common morbidities that may influence prognosis of infectious diseases. However, some previously published literature had suggested that hypothyroidism may not be affecting outcomes of COVID-19 disease. Objective of this study was to analyze the outcomes of COVID-19 patients with pre-existing hypothyroidism and further suggesting determinants of worse outcomesMethods: This retrospective cohort study was carried out at one of largest Dedicated COVID-19 Hospital in Mumbai, India. Of the 16306 patients that got admitted at this hospital in year 2020, all those having hypothyroidism were included. Bivariate analysis was performed using Chi-square test and Multivariate analysis was performed using multiple logistic regression.Results: A total of 251 patients were having pre-existing hypothyroidism (1.54%). More females had hypothyroidism (73.7%) while death rate was more in males (26.3%). ICU admissions (27.5%) and death proportions (18.3%) were significantly more in hypothyroidism. Diabetes and hypertension were common concomitant Co-morbidities and odds ratios for death for diabetes group, hypertension group and diabetes+hypertension group were 4.9, 8.1 and 4.4 respectively in comparison to those having exclusive hypothyroidism.Conclusions: This study deals with an important topic of co-existing Hypothyroidism in COVID-19 patients and we can conclude that patients with Hypothyroidism must be considered to be at risk of severe outcomes. Furthermore, age, male gender and presence of concomitant Co-morbidities increase the risk of worse outcome.


2021 ◽  
Vol 10 (1) ◽  
pp. 74-77
Author(s):  
Cahya Novenita Azzahra ◽  
Widyawati Widyawati ◽  
Liza Afriliana ◽  
Julian Dewantiningrum

AbstractIntroduction : Melasma is one of the most common hyperpigmentation disorders among womans, the common hyperpigmentation patches which commonly found on face especially on sunlight exposured area. One of the factors causing melasma is the use of oral contraceptives which cause the buildup of the hormones estrogen and progesterone on the skin.Objectives : Thus, the aim of the study is to analyze the association between duration of contraceptive pills use and melasma.Methods : This study used a cross-sectional design. The research was conducted in May-July 2020. The subjects were 36 womans aged 30-55 years old and oral contraceptive acceptors that qualify inclussion criteria and not eligible exclussion criteria. The data was collected primarily using questionnaires. Physical examinations were done through observation with a photo of the respondents. Data analysis using the Chi Square test with a significance value p <0,05.Results : Based on the results of this study, the significance of 0.017 less than 0.05 which indicates a relationship between variables duration of contraceptive pills use and melasma. Conclusions : This study shows a association between duration of contraceptive pills use and melasmaKeywords : melasma, contraceptive pills.


2016 ◽  
Vol 9 (1) ◽  
pp. 21-23
Author(s):  
Rahul Shivaraj ◽  
Cimona Dsouza ◽  
George Pinto

ABSTRACT Objective The superior attachment of the uncinate process and the agger nasi cell are important landmarks in frontal sinus surgery and are in close relation with each other. The aim of this study is to investigate the relationship between the two. Study design A retrospective radiological study. Materials and methods A total of 50 patients with features of chronic sinusitis were evaluated radiographically, i.e., by computed tomography. Hundred sides, i.e., 50 scans, were evaluated for superior attachment of the uncinate process and the presence of agger nasi. Chi-square test was used as a statistical tool for eliciting the relationship between the two. Results The agger nasi cell was found in 68 (68%) of 100 sides. The prevalence of agger nasi cell according to the superior attachment of uncinate process types was 64.1% for lamina papyracea, 79.41% for skull base, and 53.84% for middle turbinate. The presence of agger nasi cell according to the superior attachment types of uncinate process was not statistically significant (X2 = 3.5925, p = 0.16592). Conclusion The agger nasi cell was found in 68 sides (68%), and there was no statistical significance between the superior attachment of the uncinate process and the presence of agger nasi cell. How to cite this article Shivaraj R, Dsouza C, Pinto G. Influence of Superior Attachment of the Uncinate Process on the Presence of Agger Nasi. Clin Rhinol An Int J 2016;9(1):21-23.


1999 ◽  
Vol 85 (3_suppl) ◽  
pp. 1154-1156 ◽  
Author(s):  
Lorette Oden ◽  
James H. Price

The purpose was to examine the effectiveness of a modest monetary incentive ($1) and none in increasing the response rate of a mail survey to 600 nurse practitioners. The response rate in the incentive group was 81% and 66% in the control group, significant by chi-square test. The most cost effective survey technique for increasing the response rate of nurse practitioners was to code the envelopes and eliminate the monetary incentive.


2021 ◽  
Vol 9 (05) ◽  
pp. 2226-2235
Author(s):  
Aghalya V ◽  
Kasi Raman R ◽  
Kottathai S ◽  
Indhuja M

Competency mapping is a process through which one assesses and determines one’s strengths as an individual worker and in some cases, as part of an organization. It generally examines two areas: emotional intelligence or emotional quotient (EQ), and strengths of the individual in areas like team structure, leadership, and decision-making. The significant of differentiating competencies into different types such as conceptual, technical, contextual, interpersonal, etc. has gained momentum. Consequently, understanding the abilities, intentions, concealed possibilities, qualities of the people working in the association is critical. Every job has its own profile and specification. The research involved a survey in which total of two hundred and fifty employees drawn from various spinning mills in Rajapalayam were used as subjects. It is examined with the help of statistical tool together with various demographical factors was also studied using simple Percentage analysis, Weighted Average and Chi – square test. Data was collected through questionnaire and analyzed through SPSS. The chi-square analysis shows that there is significant Relationship between age of the respondents and knowledge of the respondents and also shows that there is significant Relationship between experience of the respondents and job performance of the respondents.


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