scholarly journals Clinicopathological study of thyroid swellings

2020 ◽  
Vol 6 (5) ◽  
pp. 974
Author(s):  
Anchal Gupta ◽  
Padam Singh Jamwal
Keyword(s):  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Clinical Problem ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Functional Abnormality ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Diseases of the thyroid continue to be a common clinical problem having a prevalence rate of 4 to 7% in the general population.</p><p class="abstract"><strong>Methods:</strong> This retrospective study was conducted in the Department of ENT, Head and Neck Surgery, SMGS Hospital, Jammu from January 2018 to January 2020. A thorough history taking, meticulous clinical examination, routine hematological and biochemical investigations were done in all the patients. General examination of the patient was done and looked for thyroid functional abnormality followed by local examination was carried out to locate and identify the site of the swelling, shape, size and consistency of the thyroid swelling and clinical diagnosis was made. All thyroid swelling cases were subjected to fine needle aspiration cytology (FNAC). The type of thyroidectomy is based on the size and type of thyroid whether neoplastic or non-neoplastic. All the specimens were sent for histopathological examination.  </p><p class="abstract"><strong>Results:</strong> Out of 60 patients in the study, 56 were females and only 4 were males. The most common age group was 31 to 40 years seen in 24 (40%) patients. The most common presenting symptom was swelling in the neck seen in 58 (96.67%) patients. The most common diagnosis on FNAC was colloid goiter seen in 40 (66.67%) patients. The most common was benign nodular colloid goiter seen in 35 (58.33%) patients.</p><p class="abstract"><strong>Conclusions:</strong> Fine needle aspiration is a very useful and indispensible test in the diagnosis of thyroid lesions.</p>

scholarly journals Patterns of lymphadenopathy on fine needle aspiration cytology in eastern Nepal

2015 ◽  
Vol 5 (10) ◽  
pp. 814-816
Author(s):  
N Mainali ◽  
RB Suwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Clinical Problem ◽  
Needle Aspiration ◽  
Cervical Region ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Needle Aspiration Cytology ◽  
Tubercular Lymphadenitis

BACKGROUND: Lymphadenopathy is a commonly encountered clinical problem. Fine needle aspiration cytology offers the alternative of an immediate, preliminary, although not always specific diagnosis with little trauma and cost, thus providing ample information for further management and reduce the amount of open biopsy.MATERIAL AND METHODS:  FNAC was performed using 21 gauge needle attached with 10ml disposable needle. Slides were prepared, two were air dried and stained with field stain where as two were fixed in ethanol and was stained with PAP stain. One slide was stained with Ziehl-Neelson stain. Field and PAP stained slide were reviewed and diagnosed by Pathologist.RESULT: Out of the 225 patients, reactive lymphadenitis was the most common diagnosis (54.2%), followed by tubercular lymphadenitis (33.44%). Among the age group percentage of tubercular lymphadenitis was more in 210-30 years of age.  Majority of the metastatic carcinoma was in cervical region, comprising mainly squamous cell carcinoma.CONCLUSION: Reactive lymphadenitis was the most common cause of lymphadenopathy especially in case of children. In case of older population, definite pathology for lymph node enlargement was found in most of the cases. Hence FNAC is warranted in lymphadenopathy, as it is simple yet of great diagnostic value.

scholarly journals Comparative study of fine needle aspiration cytology and histopathology of thyroid swellings in tertiary health centre

2021 ◽  
Vol 8 (1) ◽  
pp. 53
Author(s):  
Gangadhara K. S. ◽  
Chaitanya Vadva ◽  
Sridhara S.
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Health Centre ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

<p><strong>Background: </strong>Thyroid swelling being the most common presentation in ENT clinical practice, a prospective study was done to assess the role of Fine needle aspiration cytology in diagnosing the nature of thyroid swellings and comparing its results with histopathological examination findings.<strong></strong></p><p><strong>Methods: </strong>This is a prospective institutional based study comparing cytology and corresponding histopathology findings reported in 60 cases of thyroid swelling. The statistical analysis included sensitivity, specificity, positive predictive value, negative predictive value and accuracy in thyroid swelling.<strong></strong></p><p><strong>Results: </strong>Out of 60 cases, FNAC showed 93.3% and 6.6% of benign and malignant cases respectively whereas HPE showed 86.7% and 13.3% of benign and malignant cases respectively. On FNAC-HPE correlation using HPE as standard reference the diagnostic accuracy of present study is 91.66%.<strong></strong></p><p><strong>Conclusions: </strong>It was observed that FNAC is a reliable tool, safe and accurate method in evaluating thyroid swelling thus having great influences in treatment decision. Thus FNAC is the investigation of choice in thyroid swellings with excellent patient compliance, simple, safe and cost effective.<strong></strong></p>

scholarly journals Study of Correlation of Preoperative Fine Needle Aspiration Cytology with Histopathological Examination in Thyroid Swellings

2017 ◽  
Vol 7 (1) ◽  
pp. 16-19
Author(s):  
Sri Lekha Bodepudi ◽  
KASSN Kalyan ◽  
Ramarao Peddi
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Histopathological Analysis ◽  
Histopathological Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

ABSTRACT Introduction Though fine needle aspiration cytology (FNAC) for thyroid is acclaimed as a gold standard before going for intervention, there are some limitations with respect to tissue availability, technique, skill of performer, etc. So, a cross-sectional study was conducted to determine the accuracy of FNAC in diagnosis of thyroid swelling and to assess the correlation between preoperative cytopathological diagnosis and postoperative histopathological diagnosis. Materials and methods Data collected from records in the time period of 3 years, i.e., from August 2012 to August 2015, were evaluated and analyzed. Results A total number of 93 cases were included in the study of which majority were females with frequency of 84.94%, most of the incidence of thyroid swellings occur in the age group of 40 to 50 years. Overall mismatch between histopathological examination and FNAC was 43 out of 93 and of which 7 were major and 36 were minor mismatch. Sensitivity of patients having malignancy with positive FNAC is 82.35% from the study and specificity of patients with nonmalignant thyroid disease and positive cytology is 95.18%. Conclusion It was observed that FNAC is a reliable, safe, and accurate method as a first line of evaluation in thyroid swelling before the surgery. Fine needle aspiration cytology is more sensitive in detecting thyroid gland malignancy but still correlation is always necessary and therefore, histopathological analysis still remains essential for final diagnosis. How to cite this article Bodepudi SL, Kalyan KASSN, Peddi R. Study of Correlation of Preoperative Fine Needle Aspiration Cytology with Histopathological Examination in Thyroid Swellings. Int J Phonosurg Laryngol 2017;7(1):16-19.

scholarly journals Comparative study of FNAC and histopathology in the diagnosis of thyroid swelling

1970 ◽  
Vol 16 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Md Shafiqul Islam ◽  
Belayat Hossain Siddiquee ◽  
Nasima Akhtar ◽  
Kazi Shameemus Salam ◽  
Mohammad Aktaruzzaman
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Follicular Adenoma ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Histopathological Analysis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

The objective of this study was to determine the efficacy of fine needle aspiration cytology indiagnosis and management of thyroid swelling. The study evaluated the predictive value ofPre operative fine needle aspiration cytology (FNAC) in surgical decision making, by comparingthis (FNAC) with the post operative histopathological diagnosis.Ninety patients who underwent thyroidectomy between Jan-2007 to Dec-2008 were analysedin the department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh MujibMedical University, Dhaka. All the patients underwent pre operative FNAC were included inthis study.FNAC was accurate in 85 (94.44%) patients. Failure were mainly noted in cases of follicularneoplasm (lesion). Our result indicates that FNAC is helpful in the diagnosis and surgicalplanning of thyroid swelling. However, histopathological analysis is still remaining essential todistinguish follicular adenoma from follicular carcinoma.Key words: FNAC; Histopathology; Thyroid swellingDOI: 10.3329/bjo.v16i1.5779Bangladesh J Otorhinolaryngol 2010; 16(1): 35-43

scholarly journals Correlation of Fine Needle Aspiration Cytology with Histopathological Findings in the Diagnosis of Thyroid Swellings – A One Year Study in a Tertiary Care Hospital, Hyderabad

2021 ◽  
Vol 8 (18) ◽  
pp. 1246-1251
Author(s):  
Keerthana Muppidi ◽  
Vidya Kedarisetti ◽  
Kanya Kumari Mahankali
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Nodular Goitre ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also done and correlated with FNAC findings. Sensitivity, specificity and accuracy were calculated. RESULTS Age of the patients varied from 20 - 69 yrs. Most of them were in the age group of 30 - 39 years and 50 - 59 years. The ratio of male to female was 1:4.9. Swelling of the neck was the most common presentation in most of the patients. On FNAC 33 (70.2 %) cases were diagnosed as colloid nodular goitre, 04 (8.5 %) as autoimmune thyroiditis, 08 (17.0 %) as follicular neoplasm, 01 (2.1 %) as suspicious of malignancy, 01 (2.1 %) as papillary carcinoma. On histopathological examination 25 (53.2 %) cases were diagnosed as colloid nodular goitre, 01 (2.1 %) as fibrous thyroiditis, 01 (2.1 %) as Graves’ disease, 07 (14.9 %) as Hashimoto’s’ thyroiditis, 06 (12.8 %) as follicular adenoma, 01 (2.1 %) as follicular carcinoma, 04 (8.5 %) as papillary carcinoma and 02 (4.2 %) as NIFTP (noninvasive follicular thyroid neoplasm with papillary like nuclear features). The overall sensitivity was 69.2 %, specificity was 97.0 % and accuracy was 89.3 %. CONCLUSIONS FNAC is a minimally invasive, highly accurate and cost-effective procedure. FNAC helps the clinician to diagnose malignant lesions with confidence. It has high rates of specificity and accuracy but comparatively has less sensitivity. However, it is very important for the management of patients with thyroid swelling. KEYWORDS Fine Needle Aspiration, Prospective Study, Sensitivity, Specificity, Thyroid Swelling

scholarly journals Cysticercosis: Hooked by a Hooklet on Fine Needle Aspiration Cytology—A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Manav Sawhney ◽  
Shubhra Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Bladder Wall ◽  
Clinical Manifestations ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Muscle Involvement ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Cysticercosis is a systemic parasitic disease caused by the larval form of cestodeT. solium. It has a worldwide distribution and is potentially harmful with variable clinical manifestations. The patient most commonly presents with subcutaneous and muscle involvement in the form of nodular lesions. The other most commonly involved sites include eye, brain, bladder wall, and heart. Cysticercosis can be diagnosed on serology, and radiologically but confirmatory diagnosis is based on histopathological examination of the involved tissue biopsy specimen. Fine needle aspiration cytology is a useful low-cost outpatient procedure tool for preoperative diagnosis of cysticercosis and is absolutely essential for diagnosis of the parasitic lesions in a peripheral hospital, one like ours.

scholarly journals A case report of 29 year old male patient with breast carcinoma: diagnosed on fine needle aspiration cytology

2019 ◽  
Vol 8 (1) ◽  
pp. 375
Author(s):  
Komal Patel ◽  
Pallavi Chaudhri ◽  
Siddhi M. Patel
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Male Breast ◽  
Breast Cancers ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology

Breast cancer has been considered a female dominated disease. Carcinoma of male breast is a rare disease representing 1% of all breast cancers and less than 1 % of all cancers in men. The mean age at presentation is mainly in sixties. We here present a case of male breast cancer presented at very young age of 29 years, diagnosed on fine needle aspiration which was confirmed later on histopathological examination.

scholarly journals Fine needle aspiration cytology in feline skeletal muscle as a diagnostic tool for extramedullary plasmacytoma

2017 ◽  
Vol 69 (3) ◽  
pp. 587-592
Author(s):  
D.B. Martins ◽  
C.K. Rossato ◽  
S.L. Silva ◽  
S.S.N. Almeida ◽  
L.S. Ribeiro
Keyword(s):  
Skeletal Muscle ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Extramedullary Plasmacytoma ◽  
Feline Leukemia Virus ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

ABSTRACT Extramedullary noncutaneous plasmacytoma (ENP) is a myeloproliferative disorder of plasma cells that rarely affects cats. This paper describes an ENP case revealed by fine needle aspiration cytology (FNAC) of the mass in the skeletal muscle of an 8-month-old, male, mixed breed cat, which had a nodule in the left hind limb. The rapid immunoassay test confirmed the presence of feline leukemia virus (FeLV). The animal necropsy macroscopically showed the nodule came from the semimembranosus muscle. Histopathological examination ratified the cytological findings. Thus, this paper alerts to the existence of plasmacytoma located in the skeletal muscle of feline species. FNAC is a quick and efficient method for diagnosis of ENP.

scholarly journals Clinical profile of cervical lymphadenopathy and to find diagnostic efficacy of fine-needle aspiration cytology, ultrasonography and histopathological examination

2020 ◽  
Vol 6 (3) ◽  
pp. 551
Author(s):  
Nitin Sharma ◽  
Maya Singh ◽  
Pritosh Sharma ◽  
Rahul Nahar ◽  
V. P. Goyal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Tuberculous Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Cervical lymphadenopathy is the sign of a disease process which involves lymph nodes that are anomalous in uniformity and dimensions. It is very vital to exercise fine-needle aspiration biopsy, histopathological investigation, and ultrasonography for the diagnosis of palpable lesions.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study of 12-month duration from January 2018 to December 2018 in 61 patients presenting with cervical lymphadenopathy admitted in the ENT Department at Geetanjali Medical College and Hospital, Udaipur.  </p><p class="abstract"><strong>Results:</strong> In biopsy, most common diagnosis was chronic granulomatous lymphadenitis i.e. in 62.3% of the patients. As compared to biopsy, fine-needle aspiration cytology (FNAC) showed chronic granulomatous lymphadenitis in 46% of the patients, with overall sensitivity of 91.1%, and specificity of 60.0%. and accuracy of 88.5%. Whereas ultrasonography (USG) reported, 64% cervical lymphadenopathy in patients, with overall sensitivity came out to be 91.1%, specificity to be 40.0%, accuracy was 86.9%.</p><p class="abstract"><strong>Conclusions:</strong> Present study showed that biopsy is the gold standard procedure for diagnosis of cervical lymphadenopathy lesions followed by FNAC, USG. Tuberculous lymphadenitis was most common diagnosis made by the diagnostic modalities.</p>

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