A Nazarov‐Ene Tandem Reaction for the Stereoselective Construction of Spiro Compounds

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.

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Facile Regioselective Synthesis of Pyrrolo-Pyrones: Tandem Reaction of 4- N-(4 -Aryloxy-2 -ynyl), N-Methyl Pyran-2-Ones with 3-Chloroperoxybenzoic Acid (Experimental Section)

Letters in Organic Chemistry ◽

10.2174/157017805774717580 ◽

2005 ◽

Vol 2 (8) ◽

pp. 739-741 ◽

Cited By ~ 1

Author(s):

Krishna Majumdar ◽

Habibur Rahaman ◽

Brindaban Roy

Keyword(s):

Regioselective Synthesis ◽

Tandem Reaction ◽

Experimental Section

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Hosoya polynomials of general spiro hexagonal chains

Filomat ◽

10.2298/fil1401211l ◽

2014 ◽

Vol 28 (1) ◽

pp. 211-215 ◽

Cited By ~ 2

Author(s):

Xianyong Li ◽

Xiaofan Yang ◽

Guoping Wang ◽

Rongwei Hu

Keyword(s):

Organic Chemistry ◽

Benzene Ring ◽

Spiro Compounds

Spiro hexagonal chains are a subclass of spiro compounds which are an important subclass of Cycloalkynes in Organic Chemistry. This paper addresses general spiro hexagonal chains in which every hexagon represents a benzene ring, and establishes the formulae for computing the Hosoya polynomials of general spiro hexagonal chains.

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Synthesis of 1,2,3-Triazole-Fused Indole Derivatives via Copper-Catalyzed Cascade Reaction

Synthesis ◽

10.1055/a-1364-9308 ◽

2021 ◽

Author(s):

Fengtao Zhou ◽

Qiuyu Zhang ◽

Kashif Majeed ◽

Bangjie Liu

Keyword(s):

Quantum Efficiency ◽

Photophysical Properties ◽

Cascade Reaction ◽

Tandem Reaction ◽

Indole Derivatives ◽

Wide Range

AbstractA copper-catalyzed tandem reaction has been developed for the synthesis of 1,2,3-triazole-fused indole derivatives. This protocol allowed us to access a wide range of 1,2,3-triazole-fused indole derivatives in moderate to excellent yields. The 1,2,3-triazole-fused indole derivatives emit blue and greenish light when excited at 365 nm. The products were further explored for their quantum efficiency and photophysical properties.

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Synthesis of N-(Isoquinolin-1-yl)sulfonamides via Ag2O-Catalyzed Tandem Reaction of ortho-Alkynylbenzaldoximes with Benchtop Stabilized Ketenimines

Organic Letters ◽

10.1021/acs.orglett.1c00937 ◽

2021 ◽

Author(s):

Sepideh Hayatgheybi ◽

Hormoz Khosravi ◽

Hossein Zahedian Tejeneki ◽

Frank Rominger ◽

Hamid Reza Bijanzadeh ◽

...

Keyword(s):

Tandem Reaction

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Assembly of Fluorinated Chromanones via Enantioselective Tandem Reaction

Chemical Communications ◽

10.1039/d1cc01187a ◽

2021 ◽

Author(s):

Mengxue Lu ◽

Zongli Xiong ◽

Yuqiao Zhou ◽

Xin Wang ◽

Xiaoyi Li ◽

...

Keyword(s):

Enantioselective Synthesis ◽

Tandem Reaction ◽

Unsaturated Aldehydes ◽

Stereogenic Centers ◽

First Time

The enantioselective synthesis of fluorinated tricyclic chromanones with multiple vicinal stereogenic centers has been realized for the first time, through the tandem reaction between 2-fluorinated 1-(2-hydroxyaryl)-1,3-diketones and α,β-unsaturated aldehydes. In...

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Transition metal-free approach to azafluoranthene scaffolds by aldol condensation/[1+2+3] annulation tandem reaction of isocyanoacetates with 8-(alkynyl)-1-naphthaldehydes

Chemical Communications ◽

10.1039/d1cc01015h ◽

2021 ◽

Author(s):

Penghui Dong ◽

Kashif Majeed ◽

lingna Wang ◽

Zijian Guo ◽

Fengtao Zhou ◽

...

Keyword(s):

Transition Metal ◽

Aldol Condensation ◽

Domino Reaction ◽

Tandem Reaction ◽

Metal Free ◽

Successive Formation ◽

General Synthesis

A transition metal-free aldol condensation/[1+2+3] annulation reaction of isocyanoacetates with 8-(alkynyl)-1-naphthaldehydes has been developed for the general synthesis of azafluoranthenes. This domino reaction enables successive formation of three new bonds...

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