ChemInform Abstract: EXCHANGEABLE PROTON NMR WITHOUT BASE-LINE DISTORSION, USING NEW STRONG-PULSE SEQUENCES

1983 ◽  
Vol 14 (12) ◽  
Author(s):  
P. PLATEAU ◽  
M. GUERON
Keyword(s):  
Pulse Sequences ◽  
Proton Nmr ◽  
Base Line ◽  
Exchangeable Proton

Exchangeable proton NMR without base-line distorsion, using new strong-pulse sequences

1982 ◽  
Vol 104 (25) ◽  
pp. 7310-7311 ◽  
Author(s):  
Pierre Plateau ◽  
Maurice Gueron
Keyword(s):  
Pulse Sequences ◽  
Proton Nmr ◽  
Base Line ◽  
Exchangeable Proton

Assignment of proximal histidyl imidazole exchangeable proton NMR resonances to individual subunits in hemoglobins A, Boston, Iwate and Milwaukee

1980 ◽  
Vol 96 (3) ◽  
pp. 1172-1177 ◽  
Author(s):  
Gerd N. La Mar ◽  
Kiyoshi Nagai ◽  
Thomas Jue ◽  
David L. Budd ◽  
K. Gersonde ◽  
...  
Keyword(s):  
Proton Nmr ◽  
Exchangeable Proton

Evaluation of pulse sequences used for magnetic resonance sialography

2001 ◽  
Vol 30 (5) ◽  
pp. 276-284 ◽  
Author(s):  
M Sakamoto ◽  
T Sasano ◽  
S Higano ◽  
S Takahashi ◽  
T Nagasaka ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Pulse Sequences ◽  
Magnetic Resonance Sialography

Vasoactive intestinal contractor (VIC) peptide structure in solution as determinated by proton NMR

1992 ◽  
Vol 89 ◽  
pp. 175-181 ◽  
Author(s):  
A Aumelas ◽  
L Chiche ◽  
E Brun ◽  
E Mahé ◽  
D Le Nguyen ◽  
...  
Keyword(s):  
Proton Nmr ◽  
Peptide Structure ◽  
Structure In Solution

Benzene confined in MCM-41 below its melting point : A proton NMR study

2000 ◽  
Vol 10 (PR7) ◽  
pp. Pr7-99-Pr7-102 ◽  
Author(s):  
G. Dosseh ◽  
D. Morineau ◽  
C. Alba-Simionesco
Keyword(s):  
Melting Point ◽  
Proton Nmr ◽  
Nmr Study ◽  
Mcm 41

On the Fibrinolytic System in Aged Rats, and Its Reactivity to Endotoxin and Cytokines

1992 ◽  
Vol 67 (06) ◽  
pp. 697-701 ◽  
Author(s):  
J J Emeis ◽  
A Brouwer ◽  
R J Barelds ◽  
M A Horan ◽  
S K Durham ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Fibrinolytic Activity ◽  
Fibrinolytic System ◽  
Tissue Type ◽  
High Dose ◽  
Base Line ◽  
Aged Rats ◽  
Tissue Type Plasminogen Activator ◽  
Young Rats ◽  
Type Plasminogen Activator

SummaryAged rats are more susceptible to endotoxin-induced effects, including microthrombosis and platelet aggregation, than are young rats. To investigate whether changes in the fibrinolytic system might be involved, we investigated the fibrinolytic activity in plasma euglobulin fractions and tissues (lung and heart) of young (6-months old) and aged (24-months old) rats under baseline conditions and after challenge with endotoxin. Aged rats had lower plasma levels of tissue-type plasminogen activator (t-PA) and of urokinase-type PA (u-PA) activity. PA inhibitor (PAI) activity was higher in the plasma of aged rats, as was t-PA activity in lung and heart.Rats were treated with either a low dose (1 μg/kg) or a high dose (10 mg/kg) of endotoxin. Both treatments induced a transient phase of increased blood fibrinolytic activity, as evidenced by higher levels of tissue-type plasminogen activator (t-PA) activity and decreased levels of PA inhibitor (PAI) activity. Over time, the fibrinolytic activity decreased, probably due to increased levels of PA inhibitor.Both the early increase in t-PA activity, and the subsequent increase in PAI activity, were more pronounced in the aged rats, as compared with the younger rats, after the high dose of endotoxin. The aged rats also responded to an injection of interleukin-1β or tumor necrosis factor-α with a larger increase of PAI activity than did the younger rats.Together the data suggest that, compared to young rats, aged rats have a decreased base-line plasma fibrinolytic activity, while their fibrinolytic system is more responsive to challenge by endotoxin and cytokines.

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