ChemInform Abstract: Novel Selective and Partial Agonists of 5-HT3 Receptors. Part 1. Synthesis and Biological Evaluation of Piperazinopyrrolothienopyrazines.

S. RAULT; J.-C. LANCELOT; H. PRUNIER; M. ROBBA; P. RENARD; P. DELAGRANGE; B. PFEIFFER; D.-H. CAIGNARD; B. GUARDIOLA-LEMAITRE; M. HAMON

doi:10.1002/chin.199635160

ChemInform Abstract: Novel Selective and Partial Agonists of 5-HT3 Receptors. Part 1. Synthesis and Biological Evaluation of Piperazinopyrrolothienopyrazines.

ChemInform ◽

10.1002/chin.199635160 ◽

2010 ◽

Vol 27 (35) ◽

pp. no-no

Author(s):

S. RAULT ◽

J.-C. LANCELOT ◽

H. PRUNIER ◽

M. ROBBA ◽

P. RENARD ◽

...

Keyword(s):

Biological Evaluation ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARγ with potential anti-diabetic efficacy

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113542 ◽

2021 ◽

pp. 113542

Author(s):

Fengyu Huang ◽

Zhiping Zeng ◽

Weidong Zhang ◽

Zhiqiang Yan ◽

Jiayun Chen ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of novel m-carborane-containing estrogen receptor partial agonists as SERM candidates

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.05.083 ◽

2015 ◽

Vol 25 (16) ◽

pp. 3213-3216 ◽

Cited By ~ 8

Author(s):

Kiminori Ohta ◽

Takumi Ogawa ◽

Asako Kaise ◽

Yasuyuki Endo

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Novel Selective and Partial Agonists of 5-HT3Receptors. Part 1. Synthesis and Biological Evaluation of Piperazinopyrrolothienopyrazines

Journal of Medicinal Chemistry ◽

10.1021/jm950543x ◽

1996 ◽

Vol 39 (10) ◽

pp. 2068-2080 ◽

Cited By ~ 49

Author(s):

Sylvain Rault ◽

Jean-Charles Lancelot ◽

Hervé Prunier ◽

Max Robba ◽

Pierre Renard ◽

...

Keyword(s):

Biological Evaluation ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

2-Phenylcyclopropylmethylamine Derivatives as Dopamine D2 Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c01327 ◽

2021 ◽

Author(s):

Wenzhong Yan ◽

Luyu Fan ◽

Jing Yu ◽

Ruiquan Liu ◽

Huan Wang ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Biological Evaluation ◽

Design Synthesis ◽

Partial Agonists ◽

Dopamine D2 ◽

Synthesis And Biological Evaluation

Download Full-text

Design, synthesis, and biological evaluation of novel FFA1 partial agonists bearing oxime ether scaffold**

ChemistrySelect ◽

10.1002/slct.202104199 ◽

2022 ◽

Vol 7 (2) ◽

Author(s):

Bin Wang ◽

Zongyu Cai ◽

Siliang Chen ◽

Ya Chen ◽

Shixuan Jiao ◽

...

Keyword(s):

Biological Evaluation ◽

Oxime Ether ◽

Design Synthesis ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists

PLoS ONE ◽

10.1371/journal.pone.0162642 ◽

2017 ◽

Vol 12 (2) ◽

pp. e0162642 ◽

Cited By ~ 5

Author(s):

Katrine Qvortrup ◽

Jakob F. Jensen ◽

Mikael S. Sørensen ◽

Irene Kouskoumvekaki ◽

Rasmus K. Petersen ◽

...

Keyword(s):

Biological Evaluation ◽

New Class ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.016 ◽

2016 ◽

Vol 124 ◽

pp. 689-697 ◽

Cited By ~ 6

Author(s):

Han-Kun Zhang ◽

J. Brek Eaton ◽

Allison Fedolak ◽

Hendra Gunosewoyo ◽

Oluseye K. Onajole ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Novel and Selective Partial Agonists of 5-HT3Receptors. 2. Synthesis and Biological Evaluation of Piperazinopyridopyrrolopyrazines, Piperazinopyrroloquinoxalines, and Piperazinopyridopyrroloquinoxalines

Journal of Medicinal Chemistry ◽

10.1021/jm960501o ◽

1997 ◽

Vol 40 (12) ◽

pp. 1808-1819 ◽

Cited By ~ 50

Author(s):

Hervé Prunier ◽

Sylvain Rault ◽

Jean-Charles Lancelot ◽

Max Robba ◽

Pierre Renard ◽

...

Keyword(s):

Biological Evaluation ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of novel thio-substituted chromanes as high-affinity partial agonists for the estrogen receptor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)00679-5 ◽

2002 ◽

Vol 12 (1) ◽

pp. 17-19 ◽

Cited By ~ 5

Author(s):

Lise B Christiansen ◽

Martin Wenckens ◽

Paul S Bury ◽

Birgitte Gissel ◽

Birgit S Hansen ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

High Affinity ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text

ChemInform Abstract: Synthesis and Biological Evaluation of Novel Thio-Substituted Chromanes (VIII) as High-Affinity Partial Agonists for the Estrogen Receptor.

ChemInform ◽

10.1002/chin.200212171 ◽

2010 ◽

Vol 33 (12) ◽

pp. no-no

Author(s):

Lise B. Christiansen ◽

et al. et al.

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

High Affinity ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

Download Full-text