ChemInform Abstract: New and Unexpected Developments of the Carbanion-Mediated Sulfonate (Sulfonamide) Intramolecular Cyclization Reaction (CSIC Reaction).

ChemInform ◽  
2010 ◽  
Vol 29 (34) ◽  
pp. no-no
Author(s):  
J. L. MACRO ◽  
S. T. INGATE ◽  
P. MANZANO
Keyword(s):  
Intramolecular Cyclization ◽  
Cyclization Reaction

ChemInform Abstract: Efficient Synthesis of 2,8-Diazabicyclo(4.3.0)nonane Derivatives via Intramolecular Cyclization Reaction.

ChemInform ◽  
2010 ◽  
Vol 27 (7) ◽  
pp. no-no
Author(s):  
J. W. LEE ◽  
H. J. SON ◽  
J. H. LEE ◽  
Y. E. JUNG ◽  
G. J. YOON ◽  
...  
Keyword(s):  
Intramolecular Cyclization ◽  
Cyclization Reaction ◽  
Efficient Synthesis

Nerve agent simulant diethyl chlorophosphate detection using a cyclization reaction approach with high stokes shift system

2017 ◽  
Vol 41 (4) ◽  
pp. 1653-1658 ◽  
Author(s):  
Yoon Jeong Jang ◽  
Sandip V. Mulay ◽  
Youngsam Kim ◽  
Perman Jorayev ◽  
David G. Churchill
Keyword(s):  
Fluorescent Probe ◽  
Intramolecular Cyclization ◽  
Stokes Shift ◽  
Nerve Agent ◽  
Cyclization Reaction ◽  
Selective Detection ◽  
Turn On ◽  
System P

A intramolecular cyclization reaction-based “turn-on” fluorescent probe (CoumNMe2) for selective detection of diethyl chlorophosphate (DCP) over close competitors diethyl cyanophosphonate (DECP), and diethyl methylphosphonate (DEMP) was developed.

scholarly journals A Synthesis of 4-Chloro-2-(trichloromethyl)pyrimidines and Their Study in Nucleophilic Substitution

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 530-537 ◽  
Author(s):  
Moisés Romero-Ortega ◽  
Michelle Trujillo-Lagunas ◽  
Ignacio Medina-Mercado ◽  
Ivann Zaragoza-Galicia ◽  
Horacio Olivo
Keyword(s):  
Nucleophilic Substitution ◽  
Intramolecular Cyclization ◽  
Nitrogen Heterocycles ◽  
Cyclization Reaction ◽  
Substitution Reactions ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Acyl Chlorides ◽  
Nucleophilic Substitution Reactions ◽  
One Pot Synthesis

A convenient two-step, one-pot synthesis of 4-chloro-2-(trichloromethyl)pyrimidines starting from 2-(trichloromethyl)-1,3-diazabutadienes is described. These nitrogen heterocycles were prepared by a sequential acylation/intramolecular cyclization reaction between 2-(trichloromethyl)-1,3-diazabutadienes and acyl chlorides in the presence of triethylamine followed by treatment with POCl3. This is the first report for the synthesis of this type of 4-chloro-2-(trichloromethyl)pyrimidine derivatives and serves as a source for a wide variety of other substituted pyrimidines by nucleophilic substitution reactions.

Prodrug Forms of Peptidomimetic HIV Protease Inhibitors Using Intramolecular Cyclization Reaction

2001 ◽  
pp. 650-651
Author(s):  
Yoshiaki Kiso ◽  
Hikaru Matsumoto ◽  
Tomonori Hamawaki ◽  
Youhei Sohma ◽  
Tooru Kimura ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Intramolecular Cyclization ◽  
Cyclization Reaction ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors

Synthesis and conformational studies of 9-benzyloxy-18-substituted [3.3]metacyclophanes

2015 ◽  
Vol 93 (11) ◽  
pp. 1161-1168 ◽  
Author(s):  
M. Monarul Islam ◽  
Tomiyasu Hirotsugu ◽  
Taisuke Matsumoto ◽  
Junji Tanaka ◽  
Takehiko Yamato
Keyword(s):  
Solid State ◽  
Intramolecular Cyclization ◽  
Acid Treatment ◽  
Room Temperature ◽  
Coupling Reaction ◽  
Chair Conformation ◽  
Cyclization Reaction ◽  
Conformational Studies ◽  
X Ray ◽  
H Nmr

A series of syn-[3.3]metacyclophanes (MCPs) containing internal substituted benzyloxy group have been synthesized by the modified TosMIC coupling reaction followed by acid treatment and Wolff–Kishner reduction. anti-Mono- and di-benzyloxy[3.3]MCPs are synthesized by O-benzylation of the corresponding hydroxy[3.3]MCPs, which are obtained by demethylation of methoxy[3.3]MCPs with BBr3 at room temperature. An interesting and intriguing result was obtained when syn-6,15-di-tert-butyl-9-methoxy-18-methyl[3.3]MCP-2,11-dione was treated with TMSI to afford the formation of a dihydrobenzofuran ring by a nucleophilic intramolecular cyclization reaction. The 1H NMR and X-ray analysis of 6a confirms that it adopts a syn (chair–chair) conformation in both solution and solid state.

Enantioselective intramolecular cyclization of alkynyl esters catalyzed by a chiral Brønsted base

2016 ◽  
Vol 52 (33) ◽  
pp. 5726-5729 ◽  
Author(s):  
Azusa Kondoh ◽  
Hoa Thi Quynh Tran ◽  
Kyoko Kimura ◽  
Masahiro Terada
Keyword(s):  
Schiff Base ◽  
Intramolecular Cyclization ◽  
Cyclization Reaction ◽  
Base Catalyst ◽  
Chiral Schiff Base ◽  
Brønsted Base

An enantioselective intramolecular cyclization reaction of alkynyl esters was developed, which employs a Brønsted base catalyst generated in situ from a chiral Schiff base and t-BuOK.

ChemInform Abstract: Synthesis of 4,5-Disubstituted-2,7-diazabicyclo(3.3.0)octane Derivatives by Intramolecular Cyclization Reaction.

ChemInform ◽  
2010 ◽  
Vol 27 (19) ◽  
pp. no-no
Author(s):  
J. W. LEE ◽  
Y. E. JUNG ◽  
H. J. SON ◽  
G. J. YOON ◽  
M. S. KONG ◽  
...  
Keyword(s):  
Intramolecular Cyclization ◽  
Cyclization Reaction
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