Catalytic Asymmetric Synthesis of β-Hydroxy-α-amino Acid Esters by Direct Aldol Reaction of Glycinate Schiff Bases.

ChemInform ◽  
2003 ◽  
Vol 34 (9) ◽  
Author(s):  
Naoki Yoshikawa ◽  
Masakatsu Shibasaki
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Schiff Bases ◽  
Aldol Reaction ◽  
Amino Acid Esters ◽  
Catalytic Asymmetric Synthesis ◽  
Direct Aldol Reaction ◽  
Catalytic Asymmetric ◽  
Acid Esters

scholarly journals Catalytic asymmetric synthesis of CF3-substituted tertiary propargylic alcohols via direct aldol reaction of α-N3amide

2017 ◽  
Vol 8 (4) ◽  
pp. 3260-3269 ◽  
Author(s):  
Hidetoshi Noda ◽  
Fuyuki Amemiya ◽  
Karin Weidner ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Asymmetric Synthesis ◽  
Hydroxamic Acid ◽  
Aldol Reaction ◽  
Propargylic Alcohols ◽  
Catalytic Asymmetric Synthesis ◽  
Direct Aldol Reaction ◽  
Catalytic Asymmetric

The catalyst comprising Cu(ii)/chiral hydroxamic acid was found to play a bifunctional role in the direct aldol reaction of α-N3amide to alkynyl CF3ketones.

Sign in / Sign up

Export Citation Format

Share Document