ChemInform Abstract: Enantioselective Synthesis of Angularly Substituted 1-Azabicyclic Ring Systems: Dynamic Kinetic Resolution Using Aza-Cope Rearrangements.

ChemInform ◽  
2010 ◽  
Vol 41 (31) ◽  
pp. no-no
Author(s):  
Tatsuya Ito ◽  
Larry E. Overman ◽  
Jocelyn Wang
2017 ◽  
Vol 129 (9) ◽  
pp. 2494-2498 ◽  
Author(s):  
Sri Krishna Nimmagadda ◽  
Sharath Chandra Mallojjala ◽  
Lukasz Woztas ◽  
Steven E. Wheeler ◽  
Jon C. Antilla

2010 ◽  
Vol 75 (13) ◽  
pp. 4596-4599 ◽  
Author(s):  
Eric V. Johnston ◽  
Krisztián Bogár ◽  
Jan-E. Bäckvall

ChemInform ◽  
2007 ◽  
Vol 38 (6) ◽  
Author(s):  
Mercedes Amat ◽  
Oriol Bassas ◽  
Nuria Llor ◽  
Margalida Canto ◽  
Maria Perez ◽  
...  

2011 ◽  
Vol 76 (7) ◽  
pp. 919-927 ◽  
Author(s):  
Annika Träff ◽  
Carmen E. Solarte ◽  
Jan-E. Bäckvall

The synthesis of (S)-salbutamol is described. By utilizing DKR in the enantiodetermining step, employing Burkholderia cepacia lipase (PS-IM), (S)-acetate ((S)-6) was obtained in excellent enantiomeric excess (98%). The subsequent transformations yielded the salt of (S)-salbutamol with retained stereochemistry.


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