ChemInform Abstract: An Efficient Approach for the One-Pot Synthesis of Ethyl 4-Oxo-4H-benzo[d][1,3]oxazine-2-carboxylates.

The one-pot synthesis of cyclic isothioureas was reported. This method provides a straightforward and efficient approach for the synthesis of a broad range of cyclic isothioureas with yield up to 90% and in quantities up to 5 g. It is of great value for the preparation of classic organocatalysts, such as BTM (benzotetramisole) and HBTM (homobenzotetramisole).

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An Efficient Approach for the One-Pot Synthesis of Ethyl 4-Oxo-4H-benzo[d][1,3]oxazine-2-carboxylates

Heterocycles ◽

10.3987/com-11-12318 ◽

2011 ◽

Vol 83 (11) ◽

pp. 2597 ◽

Cited By ~ 3

Author(s):

Farzad Nikpour ◽

Mahnaz Sharafi-Kolkeshvandi ◽

Asrin Bahmani

Keyword(s):

One Pot ◽

Efficient Approach ◽

One Pot Synthesis ◽

The One

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A Highly Efficient Approach to the Synthesis of Complex α-Glycosyl Phosphosaccharides

10.21203/rs.3.rs-669845/v1 ◽

2021 ◽

Author(s):

Yugen Zhu ◽

Xiaojuan Zhang ◽

Yutong Yang ◽

Jiahao Ding ◽

Yun Zhao ◽

...

Keyword(s):

Phosphoric Acid ◽

Leishmania Donovani ◽

One Pot ◽

Efficient Approach ◽

Highly Efficient ◽

One Pot Synthesis ◽

The One

Abstract A highly efficient and stereoselective approach to the synthesis of biologically important and complex α-glycosyl phosphosaccharides (GPSs) has been disclosed, employing direct gold(I)-catalyzed glycosylation of the weakly nucleophilic phosphoric acid acceptors. The broad substrate scope is demonstrated with more than 45 examples, including glucose (Glc), xylose, glucouronatose, galactose (Gal), mannose (Man), rhamnose (Rha), fucose (Fuc), 2-N3-2-dexoxymannose (ManN3), 2-N3-2-dexoxyglucose (GlcN3), 2-N3-2-dexoxygalactose (GalN3) and unnatural carbohydrates. Moreover, the glycosyl phosphotriester prepared herein was successfully applied to the one-pot synthesis of a GPS from Leishmania donovani, and an effective preparation of a trisaccharide diphosphate of GPS fragments from Hansenula capsulate via iterative elongation strategy is realized.

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One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

10.26434/chemrxiv.12234665 ◽

2020 ◽

Author(s):

Lucien Caspers ◽

Julian Spils ◽

Mattis Damrath ◽

Enno Lork ◽

Boris Nachtsheim

Keyword(s):

Conformational Analysis ◽

Bronsted Acids ◽

One Pot ◽

Benzyl Alcohols ◽

Iodonium Salts ◽

Efficient Approach ◽

One Pot Synthesis ◽

Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

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An Overview of the One-pot Synthesis of Imidazolines

Current Organic Chemistry ◽

10.2174/1385272824999201001153735 ◽

2020 ◽

Vol 24 (20) ◽

pp. 2341-2355

Author(s):

Thaipparambil Aneeja ◽

Sankaran Radhika ◽

Mohan Neetha ◽

Gopinathan Anilkumar

Keyword(s):

Asymmetric Catalysis ◽

Organic Compounds ◽

Ring Opening ◽

Ecological Impact ◽

Chiral Auxiliary ◽

One Pot ◽

One Pot Synthesis ◽

The One ◽

Synthetic Intermediate ◽

Heterocyclic Moiety

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.

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