Enantiomers of C5-chiral 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives: Analytical and semipreparative HPLC separation, chiroptical properties, absolute configuration, and inhibitory activity against monoamine oxidase

Chirality ◽  
2004 ◽  
Vol 16 (9) ◽  
pp. 625-636 ◽  
Author(s):  
Roberto Cirilli ◽  
Rosella Ferretti ◽  
Bruno Gallinella ◽  
Luciana Turchetto ◽  
Adriana Bolasco ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Pyrazole Derivatives ◽  
Hplc Separation ◽  
Chiroptical Properties ◽  
Semipreparative Hplc

Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors

2010 ◽  
Vol 18 (14) ◽  
pp. 5063-5070 ◽  
Author(s):  
Franco Chimenti ◽  
Daniela Secci ◽  
Adriana Bolasco ◽  
Paola Chimenti ◽  
Arianna Granese ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
3D Qsar ◽  
Biological Evaluation ◽  
Monoamine Oxidase B ◽  
Hplc Separation ◽  
Semipreparative Hplc

Synthesis and Selective Inhibitory Activity of 1-Acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole Derivatives against Monoamine Oxidase

2004 ◽  
Vol 47 (8) ◽  
pp. 2071-2074 ◽  
Author(s):  
Franco Chimenti ◽  
Adriana Bolasco ◽  
Fedele Manna ◽  
Daniela Secci ◽  
Paola Chimenti ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Inhibitory Activity ◽  
Pyrazole Derivatives

ChemInform Abstract: Synthesis and Inhibitory Activity Against Human Monoamine Oxidase of N1-Thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole Derivatives.

ChemInform ◽  
2010 ◽  
Vol 41 (23) ◽  
pp. no-no
Author(s):  
Franco Chimenti ◽  
Simone Carradori ◽  
Daniela Secci ◽  
Adriana Bolasco ◽  
Bruna Bizzarri ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Inhibitory Activity ◽  
Pyrazole Derivatives

Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1 H )-pyrazole derivatives

2010 ◽  
Vol 45 (2) ◽  
pp. 800-804 ◽  
Author(s):  
Franco Chimenti ◽  
Simone Carradori ◽  
Daniela Secci ◽  
Adriana Bolasco ◽  
Bruna Bizzarri ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Inhibitory Activity ◽  
Pyrazole Derivatives

Semipreparative HPLC enantioseparation, chiroptical properties, and absolute configuration of two novel cyclooxygenase-2 inhibitors

Chirality ◽  
2010 ◽  
Vol 22 (1) ◽  
pp. 56-62 ◽  
Author(s):  
Roberto Cirilli ◽  
Stefano Fiore ◽  
Francesco La Torre ◽  
Elias Maccioni ◽  
Daniela Secci ◽  
...  
Keyword(s):  
Absolute Configuration ◽  
Cyclooxygenase 2 ◽  
Chiroptical Properties ◽  
Semipreparative Hplc ◽  
Cyclooxygenase 2 Inhibitors

Synthesis and Evaluation of 2-benzylidene-1-tetralone Derivatives for Monoamine Oxidase Inhibitory Activity

2018 ◽  
Vol 18 (2) ◽  
pp. 136-149 ◽  
Author(s):  
Klaudia T. Amakali ◽  
Lesetja J. Legoabe ◽  
Anel Petzer ◽  
Jacobus P. Petzer
Keyword(s):  
Monoamine Oxidase ◽  
Inhibitory Activity

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins

ChemMedChem ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Giovanna L. Delogu ◽  
Silvia Serra ◽  
Elias Quezada ◽  
Eugenio Uriarte ◽  
Santiago Vilar ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Inhibitory Activity
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