O-(Triazolyl)methyl Carbamates as a Novel and Potent Class of Fatty Acid Amide Hydrolase (FAAH) Inhibitors

Acid Amide ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Chemistry around imidazopyrazine and ibuprofen: Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2010.04.040 ◽

2010 ◽

Vol 45 (9) ◽

pp. 3564-3574 ◽

Cited By ~ 20

Author(s):

Frédéric De Wael ◽

Giulio G. Muccioli ◽

Didier M. Lambert ◽

Thérèse Sergent ◽

Yves-Jacques Schneider ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.09.086 ◽

2009 ◽

Vol 19 (23) ◽

pp. 6793-6796 ◽

Cited By ~ 7

Author(s):

Fabien Vincent ◽

Margaret T. Nguyen ◽

Daniel E. Emerling ◽

Michael G. Kelly ◽

Matthew A.J. Duncton

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Biologically Active ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.11.006 ◽

2013 ◽

Vol 21 (1) ◽

pp. 28-41 ◽

Cited By ~ 23

Author(s):

Mitsunori Kono ◽

Takahiro Matsumoto ◽

Toru Kawamura ◽

Atsushi Nishimura ◽

Yoshihiro Kiyota ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Biological Evaluation ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Sar Study ◽

Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy

Neuropharmacology ◽

10.1016/j.neuropharm.2014.11.024 ◽

2015 ◽

Vol 95 ◽

pp. 100-109 ◽

Cited By ~ 23

Author(s):

Farinaz Nasirinezhad ◽

Stanislava Jergova ◽

James P. Pearson ◽

Jacqueline Sagen

Keyword(s):

Fatty Acid ◽

Rat Model ◽

Acid Amide ◽

Sensory Neuropathy ◽

Persistent Pain ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2016.1265520 ◽

2017 ◽

Vol 32 (1) ◽

pp. 513-521 ◽

Cited By ~ 4

Author(s):

Naresh Sunduru ◽

Mona Svensson ◽

Mariateresa Cipriano ◽

Sania Marwaha ◽

C. David Andersson ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

New Class ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2011.02.052 ◽

2011 ◽

Vol 21 (8) ◽

pp. 2492-2496 ◽

Cited By ~ 40

Author(s):

Darin J. Gustin ◽

Zhihua Ma ◽

Xiaoshan Min ◽

Yihong Li ◽

Christine Hedberg ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Cover Picture: Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (ChemMedChem 9/2009)

ChemMedChem ◽

10.1002/cmdc.200990041 ◽

2009 ◽

Vol 4 (9) ◽

pp. 1385-1385

Author(s):

Federica Vacondio ◽

Claudia Silva ◽

Alessio Lodola ◽

Alessandro Fioni ◽

Silvia Rivara ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Biological Stability ◽

Structure Property ◽

Structure Property Relationships ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats

Psychopharmacology ◽

10.1007/s00213-015-4140-6 ◽

2015 ◽

Vol 233 (10) ◽

pp. 1879-1888 ◽

Cited By ~ 20

Author(s):

Leigh V. Panlilio ◽

Eric B. Thorndike ◽

Spyros P. Nikas ◽

Shakiru O. Alapafuja ◽

Tiziano Bandiera ◽

...

Keyword(s):

Working Memory ◽

Fatty Acid ◽

Acid Amide ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability

ChemMedChem ◽

10.1002/cmdc.200900120 ◽

2009 ◽

Vol 4 (9) ◽

pp. 1495-1504 ◽

Cited By ~ 28

Author(s):

Federica Vacondio ◽

Claudia Silva ◽

Alessio Lodola ◽

Alessandro Fioni ◽

Silvia Rivara ◽

...

Keyword(s):

Fatty Acid ◽

Acid Amide ◽

Biological Stability ◽

Structure Property ◽

Structure Property Relationships ◽

Amide Hydrolase ◽

Faah Inhibitors ◽

Dual Soluble Epoxide Hydrolase (sEH)/Fatty Acid Amide Hydrolase (FAAH) Inhibitors with Improved Potency Towards Rodent Species

The FASEB Journal ◽

10.1096/fasebj.2018.32.1_supplement.558.1 ◽

2018 ◽

Vol 32 (S1) ◽

Author(s):

Sean David Kodani ◽

Sung Hee Hwang ◽

Christophe Morisseau ◽

Bruce Dupree Hammock

Keyword(s):

Fatty Acid ◽

Epoxide Hydrolase ◽

Acid Amide ◽

Soluble Epoxide Hydrolase ◽

Rodent Species ◽

Amide Hydrolase ◽

Faah Inhibitors ◽