Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors

ChemMedChem ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. 678-700 ◽  
Author(s):  
Rasala Mahesh ◽  
Vadithe Lakshma Nayak ◽  
Korrapati Suresh Babu ◽  
Syed Riyaz ◽  
Thokhir Basha Shaik ◽  
...  
Keyword(s):  
Tubulin Polymerization ◽  
Design Synthesis ◽  
Tubulin Polymerization Inhibitors

Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors

2017 ◽  
Vol 15 (4) ◽  
pp. 852-862 ◽  
Author(s):  
Baijiao An ◽  
Shun Zhang ◽  
Jun Yan ◽  
Ling Huang ◽  
Xingshu Li
Keyword(s):  
Tubulin Polymerization ◽  
In Vivo Evaluation ◽  
Tubulin Polymerization Inhibitors

In this paper, a series of millepachine derivatives were synthesized and evaluated as tubulin polymerization inhibitors.

New ursolic acid derivatives bearing 1,2,3-triazole moieties: design, synthesis and anti-inflammatory activity in vitro and in vivo

2021 ◽  
Author(s):  
Tian-Yi Zhang ◽  
Chun-Shi Li ◽  
Li-Ting Cao ◽  
Xue-Qian Bai ◽  
Dong-Hai Zhao ◽  
...  
Keyword(s):  
Ursolic Acid ◽  
Inflammatory Activity ◽  
Design Synthesis ◽  
Anti Inflammatory

Thiazolidinedione “Magic Bullets” Simultaneously Targeting PPARγ and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects

2021 ◽  
Author(s):  
Kalpana Tilekar ◽  
Jessica D. Hess ◽  
Neha Upadhyay ◽  
Alessandra Lo Bianco ◽  
Markus Schweipert ◽  
...  
Keyword(s):  
Antitumor Effects ◽  
Design Synthesis
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