scholarly journals Real-time identification of liver cancers by using indocyanine green fluorescent imaging

Cancer ◽  
2009 ◽  
Vol 115 (11) ◽  
pp. 2491-2504 ◽  
Author(s):  
Takeaki Ishizawa ◽  
Noriyoshi Fukushima ◽  
Junji Shibahara ◽  
Koichi Masuda ◽  
Sumihito Tamura ◽  
...  

2009 ◽  
Vol 136 (5) ◽  
pp. A-855-A-856
Author(s):  
Takeaki Ishizawa ◽  
Noriyoshi Fukushima ◽  
Junji Shibahara ◽  
Koichi Masuda ◽  
Sumihito Tamura ◽  
...  


2015 ◽  
Vol 152 (1) ◽  
pp. 71-72 ◽  
Author(s):  
C. Lim ◽  
A. Malek ◽  
R. Martins ◽  
S. Petillon ◽  
G. Boulate ◽  
...  


VASA ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 383-388 ◽  
Author(s):  
Henrik Christian Rieß ◽  
Anna Duprée ◽  
Christian-Alexander Behrendt ◽  
Tilo Kölbel ◽  
Eike Sebastian Debus ◽  
...  

Abstract. Background: Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluorescent imaging (ICG-FI) before and after peripheral bypass grafting. Patients and methods: Indocyanine green fluorescent imaging was performed in seven patients using the SPY Elite system before and after peripheral bypass grafting for PAD (Rutherford III-VI). Visual and quantitative evaluation of tissue perfusion was assessed in an area of low perfusion (ALP) and high perfusion (AHP), each by three independent investigators. Data assessment was performed offline using a specially customized software package (Institute for Laser Technology, University Ulm, GmbH). Slope of fluorescent intensity (SFI) was measured as time-intensity curves. Values were compared to ankle-brachial index (ABI), slope of oscillation (SOO), and time to peak (TTP) obtained from photoplethysmography (PPG). Results: All measurements before and after surgery were successfully performed, showing that ABI, TTP, and SOO increased significantly compared to preoperative values, all being statistically significant (P < 0.05), except for TTP (p = 0.061). Further, SFI increased significantly in both ALP and AHP (P < 0.05) and correlated considerably with ABI, TTP, and SOO (P < 0.05). Conclusions: In addition to ABI and slope of oscillation (SOO), the ICG-FI technique allows visual assessment in combination with quantitative assessment of tissue perfusion in patients with PAD. Ratios related to different perfusion patterns and SFI seem to be useful tools to reduce factors disturbing ICG-FI measurements.



2014 ◽  
Vol 2 (4) ◽  
pp. 180-183 ◽  
Author(s):  
Yasuyuki Mitani ◽  
Akio Kubota ◽  
Masaki Ueno ◽  
Katsunari Takifuji ◽  
Takashi Watanabe ◽  
...  




Author(s):  
Misa Yoshida ◽  
Mio Tanaka ◽  
Norihiko Kitagawa ◽  
Masato Shinkai ◽  
Hiroaki Goto ◽  
...  

Background: The prognosis of metastatic hepatoblastoma remains poor; to improve it, pulmonary metastasis must be controlled. Indocyanine green (ICG) fluorescent imaging has been used recently for lung metastasectomy. The objective of our study was to clarify the usefulness of ICG imaging for lung metastasectomy of hepatoblastoma using detailed clinicopathological analysis. Procedure: Patients with hepatoblastoma who underwent resection of pulmonary metastases with ICG fluorescent imaging were studied using retrospective analysis of clinical information, a review of their surgical records, and a histological analysis of their metastatic nodules. Results: Sixteen patients were enrolled. In total, 61 ICG-imaging-guided pulmonary metastasectomies were performed, and 350 ICG-positive and 23 ICG-negative specimens were identified. Tumors were confirmed in 250 of the ICG-positive specimens, including eight nonpalpable nodules, on microscopic examination. One hundred ICG-positive specimens and histologically tumor-negative specimens showed histological changes suggesting the regression of a tumor or bloodstream disturbance. The palpable ICG-negative tumors showed more-severe atypia than the ICG-positive tumors. Conclusions: This study demonstrates the high sensitivity of ICG imaging in detecting metastatic lesions of hepatoblastoma. Histological examinations suggested that ICG imaging detects not only tumor cells, but also nontumorous pulmonary tissues affected by bloodstream disturbance. Because a number of false-positive specimens were detected, further optimization of the dose of ICG and the timing of its administration may be required for thorough metastasectomy. Several false-negative specimens were also detected, suggesting the presence of ICG-negative metastatic tumors. Palpation during operation and imaging studies remain essential for detecting metastatic lesions, even in the era of ICG imaging.



2021 ◽  
Author(s):  
Misa Yoshida ◽  
Mio Tanaka ◽  
Norihiko Kitagawa ◽  
Kumiko Nozawa ◽  
Masato Shinkai ◽  
...  


2020 ◽  
Vol 40 (10) ◽  
pp. 5823-5828
Author(s):  
KENSUKE YAMAMURA ◽  
TORU BEPPU ◽  
NOBUTAKA SATO ◽  
KOICHI KINOSHITA ◽  
ERI ODA ◽  
...  


2013 ◽  
Vol 59 (3) ◽  
pp. 631-632 ◽  
Author(s):  
Sabine Schmidt ◽  
Alban Denys ◽  
Catherine M. Pastor


2015 ◽  
Vol 221 (3) ◽  
pp. e49-e53 ◽  
Author(s):  
Takeshi Kurihara ◽  
Yo-ichi Yamashita ◽  
Yoshihiro Yoshida ◽  
Kazuki Takeishi ◽  
Shinji Itoh ◽  
...  


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