scholarly journals A phase I dose‐escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC‐223 in patients with advanced solid tumors or multiple myeloma

Cancer ◽  
2015 ◽  
Vol 121 (19) ◽  
pp. 3481-3490 ◽  
Author(s):  
Johanna C. Bendell ◽  
Robin K. Kelley ◽  
Kent C. Shih ◽  
Jennifer A. Grabowsky ◽  
Emily Bergsland ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Kinase Inhibitor ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals Phase I dose escalation study of MK-0457, a novel Aurora kinase inhibitor, in adult patients with advanced solid tumors

2010 ◽  
Vol 67 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Anne M. Traynor ◽  
Maureen Hewitt ◽  
Glenn Liu ◽  
Keith T. Flaherty ◽  
Jason Clark ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Aurora Kinase Inhibitor ◽  
Dose Escalation Study

A Phase I Dose–Escalation Study of Regorafenib (BAY 73–4506), an Inhibitor of Oncogenic, Angiogenic, and Stromal Kinases, in Patients with Advanced Solid Tumors

2012 ◽  
Vol 18 (9) ◽  
pp. 2658-2667 ◽  
Author(s):  
Klaus Mross ◽  
Annette Frost ◽  
Simone Steinbild ◽  
Susanne Hedbom ◽  
Martin Büchert ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study

2009 ◽  
Vol 66 (4) ◽  
pp. 669-680 ◽  
Author(s):  
Francisco Robert ◽  
Alan Sandler ◽  
Joan H. Schiller ◽  
Glenn Liu ◽  
Karen Harper ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors

2014 ◽  
Vol 74 (5) ◽  
pp. 917-925 ◽  
Author(s):  
Carlos R. Becerra ◽  
Paul Conkling ◽  
Nicholas Vogelzang ◽  
Hilary Wu ◽  
Shengyan Hong ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study
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