Innervation of rat iris by trigeminal and ciliary neurons expressing pChAT, a novel splice variant of choline acetyltransferase

2004 ◽  
Vol 472 (2) ◽  
pp. 232-245 ◽  
Author(s):  
Osamu Yasuhara ◽  
Yoshinari Aimi ◽  
Akira Shibano ◽  
Akinori Matsuo ◽  
Jean-Pierre Bellier ◽  
...  
2007 ◽  
Vol 50 (1) ◽  
pp. 251-255 ◽  
Author(s):  
Shin Kimura ◽  
Jean-Pierre Bellier ◽  
Akinori Matsuo ◽  
Ikuo Tooyama ◽  
Hiroshi Kimura

Neuroscience ◽  
2003 ◽  
Vol 118 (1) ◽  
pp. 243-251 ◽  
Author(s):  
H Kanayama ◽  
O Yasuhara ◽  
A Matsuo ◽  
I Tooyama ◽  
Y Aimi ◽  
...  

2003 ◽  
Vol 23 (7) ◽  
pp. 2872-2881 ◽  
Author(s):  
Osamu Yasuhara ◽  
Ikuo Tooyama ◽  
Yoshinari Aimi ◽  
Jean-Pierre Bellier ◽  
Tadashi Hisano ◽  
...  

Author(s):  
K.A. Carson ◽  
C.B. Nemeroff ◽  
M.S. Rone ◽  
J.S. Kizer ◽  
J.S. Hanker

Biochemical, physiological, pharmacological, and more recently enzyme histo- chemical data have indicated that cholinergic circuits exist in the hypothalamus. Ultrastructural correlates of these pathways such as acetylcholinesterase (AchE) positive neurons in the arcuate nucleus (ARC) and stained terminals in the median eminence (ME) have yet to be described. Initial studies in our laboratories utilizing chemical lesioning and microdissection techniques coupled with microchemical and light microscopic enzyme histo- chemical studies suggested the existence of cholinergic neurons in the ARC which project to the ME (1). Furthermore, in adult male rats with Halasz deafferentations (hypothalamic islands composed primarily of the isolated ARC and the ME) choline acetyltransferase (ChAc) activity, a good marker for cholinergic neurons, was not significantly reduced in the ME and was only somewhat reduced in the ARC (2). Treatment of neonatal rats with high doses of monosodium 1-glutamate (MSG) results in a lesion largely restricted to the neurons of the ARC.


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