Unfolding of tryptophanoctyl ester and elastic deformation of host micelles via RR´3N+…π interaction: Conceivable relevance to wrapping process of receptor mediated endocytosis

ChemPhysChem ◽  
2021 ◽  
Author(s):  
Gulmi Chakraborty ◽  
Soumik Bardhan ◽  
Swapan K. Saha
Author(s):  
Takeshi Baba ◽  
Nobuki Shiozawa ◽  
Masao Hotch ◽  
Shinichi Ohno

Endosomes are vesicular or tubular organelles that play important roles in transports of receptors and receptor―bound ligands during receptor-mediated endocytosis. The mechanisms of endocytic transports from clathrin-coated pits to lysosomes have been studied by many investigators. However, few studies were reported about the interactions between endosomes and cytoskeletons. In this study, Fc-receptor-mediated endocytosis in macrophages are investigated by quick-freezing and deep-etching (QF-DE) method combined with gold-labeled immune complex and “replica scraping method”.


2020 ◽  
Vol 48 (4) ◽  
pp. 287-314
Author(s):  
Yan Wang ◽  
Zhe Liu ◽  
Michael Kaliske ◽  
Yintao Wei

ABSTRACT The idea of intelligent tires is to develop a tire into an active perception component or a force sensor with an embedded microsensor, such as an accelerometer. A tire rolling kinematics model is necessary to link the acceleration measured with the tire body elastic deformation, based on which the tire forces can be identified. Although intelligent tires have attracted wide interest in recent years, a theoretical model for the rolling kinematics of acceleration fields is still lacking. Therefore, this paper focuses on an explicit formulation for the tire rolling kinematics of acceleration, thereby providing a foundation for the force identification algorithms for an accelerometer-based intelligent tire. The Lagrange–Euler method is used to describe the acceleration field and contact deformation of rolling contact structures. Then, the three-axis acceleration vectors can be expressed by coupling rigid body motion and elastic deformation. To obtain an analytical expression of the full tire deformation, a three-dimensional tire ring model is solved with the tire–road deformation as boundary conditions. After parameterizing the ring model for a radial tire, the developed method is applied and validated by comparing the calculated three-axis accelerations with those measured by the accelerometer. Based on the features of acceleration, especially the distinct peak values corresponding to the tire leading and trailing edges, an intelligent tire identification algorithm is established to predict the tire–road contact length and tire vertical load. A simulation and experiments are conducted to verify the accuracy of the estimation algorithm, the results of which demonstrate good agreement. The proposed model provides a solid theoretical foundation for an acceleration-based intelligent tire.


2020 ◽  
Vol 65 (1) ◽  
pp. 51-58
Author(s):  
Sava Ianici

The paper presents the results of research on the study of the elastic deformation of a flexible wheel from a double harmonic transmission, under the action of a cam wave generator. Knowing exactly how the flexible wheel is deformed is important in correctly establishing the geometric parameters of the wheels teeth, allowing a better understanding and appreciation of the specific conditions of harmonic gearings in the two stages of the transmission. The veracity of the results of this theoretical study on the calculation of elastic deformations and displacements of points located on the average fiber of the flexible wheel was subsequently verified and confirmed by numerical simulation of the flexible wheel, in the elastic field, using the finite element method from SolidWorks Simulation.


2003 ◽  
Vol 3 ◽  
pp. 52-59
Author(s):  
S.S. Komarov ◽  
N.Yu. Tsvileneva ◽  
N.I. Miskaktin

The main problems of the wave dynamics of flexible filaments and elastic membranes are solved. The reliability of the numerical algorithm proposed by the authors for calculating the elastic deformation of pneumatic structures under dynamic loading is confirmed when compared with the results of known studies obtained by analytical and numerical methods.


1983 ◽  
Vol 258 (8) ◽  
pp. 4715-4724 ◽  
Author(s):  
R D Klausner ◽  
J Van Renswoude ◽  
G Ashwell ◽  
C Kempf ◽  
A N Schechter ◽  
...  

RSC Advances ◽  
2020 ◽  
Vol 10 (67) ◽  
pp. 41249-41249
Author(s):  
Limei Tian ◽  
E. Jin ◽  
Jianfu Wang ◽  
Xiaoming Wang ◽  
Wei Bing ◽  
...  
Keyword(s):  

Correction for ‘Exploring the antifouling effect of elastic deformation by DEM–CFD coupling simulation’ by Limei Tian et al., RSC Adv., 2019, 9, 40855–40862, DOI: 10.1039/C9RA06761B.


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