Recent Advances in Small Molecule and Biological Therapeutic Approaches in the Treatment of Psoriasis

2017 ◽  
Vol 102 (1) ◽  
pp. 70-85 ◽  
Author(s):  
JG Turbeville ◽  
NU Patel ◽  
LA Cardwell ◽  
E Oussedik ◽  
SR Feldman
Keyword(s):  
Small Molecule ◽  
Therapeutic Approaches ◽  
Recent Advances

Recent Advances of p53-MDM2 Small Molecule Inhibitors (2011-Present)

2015 ◽  
Vol 22 (5) ◽  
pp. 618-626 ◽  
Author(s):  
Peng-Cheng Lv ◽  
Juan Sun ◽  
Hai-Liang Zhu
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Recent Advances

scholarly journals Recent advances in developing small-molecule inhibitors against SARS-CoV-2

2021 ◽  
Author(s):  
Rong Xiang ◽  
Zhengsen Yu ◽  
Yang Wang ◽  
Lili Wang ◽  
Shanshan Huo ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Recent Advances

Recent advances in 1,8-naphthalimide-based small-molecule fluorescent probes for organelles imaging and tracking in living cells

2021 ◽  
Vol 444 ◽  
pp. 214019
Author(s):  
Haitao Yu ◽  
Yan Guo ◽  
Wencheng Zhu ◽  
Kaden Havener ◽  
Xujun Zheng
Keyword(s):  
Small Molecule ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Recent Advances

scholarly journals Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems

2021 ◽  
Vol 50 (2) ◽  
pp. 702-734
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Ping Li ◽  
Bo Tang ◽  
Tony D. James
Keyword(s):  
Small Molecule ◽  
Biological Systems ◽  
Two Photon ◽  
Small Molecule Probes ◽  
Recent Advances ◽  
Design Construction

In this tutorial review, we will explore recent advances for the design, construction and application of two-photon excited fluorescence (TPEF)-based small-molecule probes.

Tuning metal–metal interactions for cooperative small molecule activation

2021 ◽  
Author(s):  
Qiuran Wang ◽  
Sam H. Brooks ◽  
Tianchang Liu ◽  
Neil C. Tomson
Keyword(s):  
Small Molecule ◽  
Small Molecule Activation ◽  
Feature Article ◽  
Metal Interactions ◽  
Recent Advances ◽  
Metal Metal

This Feature Article describes recent advances in the design of multinucleating ligands that support small molecule activation chemistry.

scholarly journals Small-molecule fluorescence-based probes for interrogating major organ diseases

2021 ◽  
Author(s):  
Hai-Hao Han ◽  
He Tian ◽  
Yi Zang ◽  
Adam C. Sedgwick ◽  
Jia Li ◽  
...  
Keyword(s):  
Small Molecule ◽  
Fluorescent Probes ◽  
Recent Advances ◽  
Major Organ

This tutorial review describes recent advances involving small molecule fluorescent probes designed to aid in the study of major organ diseases.

Recent Advances Toward New Small Molecule Therapies for Heart Failure

2021 ◽  
pp. 1-48
Author(s):  
David St. Jean ◽  
Justin Malinowski ◽  
Antonio Romero
Keyword(s):  
Heart Failure ◽  
Small Molecule ◽  
Recent Advances

scholarly journals Small-molecule modulators of inward rectifier K+channels: recent advances and future possibilities

2010 ◽  
Vol 2 (5) ◽  
pp. 757-774 ◽  
Author(s):  
Gautam Bhave ◽  
Daniel Lonergan ◽  
Brian A Chauder ◽  
Jerod S Denton
Keyword(s):  
Small Molecule ◽  
Inward Rectifier ◽  
K Channels ◽  
Recent Advances ◽  
Small Molecule Modulators

The Emerging Role of Epigenetic Methylation in Kidney Disease

2021 ◽  
Vol 28 ◽  
Author(s):  
Li Wen ◽  
Hong-liu Yang ◽  
Lin Lin ◽  
Liang Ma ◽  
Ping Fu
Keyword(s):  
Dna Methylation ◽  
Kidney Disease ◽  
Histone Methylation ◽  
Kidney Diseases ◽  
Therapeutic Approaches ◽  
Promoter Regions ◽  
Recent Advances ◽  
Epigenetic Methylation

: Kidney disease has complex and multifactorial pathophysiology and pathogenesis. Recent studies have revealed that epigenetic methylation changes, namely DNA methylation, histone methylation and non-histone methylation, are strongly implicated in various forms of kidney diseases. This review provides a perspective on the emerging role of epigenetic methylation in kidney disease, including the effects of DNA methylation in diverse promoter regions, regulation and implication of histone methylation, and recent advances and potential directions related to non-histone methylation. Monitoring or targeting epigenetic methylation has potential to contribute to development of therapeutic approaches for multiple kidney diseases.

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