SUMMARY
Renal iodide clearance in rats was reduced rapidly when the animals were fed a protein-depletion diet. If the iodine content of the protein-depletion diet is high, this results in an increase in the serum iodide levels to concentrations in excess of 150 μg./100 ml. Protein-bound iodine was elevated due to the accumulation of iodinated serum albumin. Thyroid hormonal iodoamino acid content was transiently depressed, presumably by the mechanism described by Wolff & Chaikoff (1948). Thyroxine metabolism was not affected except for a change in the partition of thyroxine between liver and serum. There was no evidence for pituitary involvement in the effects of protein depletion on thyroid function.
Data for the generation of RNA spatiotemporal distributions and interpretation of Chk1 and SLBP protein depletion phenotypes during Drosophila embryogenesis
