scholarly journals The mechanism by which imeglimin inhibits gluconeogenesis in rat liver cells

Author(s):  
Guillaume Vial ◽  
Frédéric Lamarche ◽  
Cécile Cottet‐Rousselle ◽  
Sophie Hallakou‐Bozec ◽  
Anne‐Laure Borel ◽  
...  
Author(s):  
Robert R. Cardell

Hypophysectomy of the rat renders this animal deficient in the hormones of the anterior pituitary gland, thus causing many primary and secondary hormonal effects on basic liver functions. Biochemical studies of these alterations in the rat liver cell are quite extensive; however, relatively few morphological observations on such cells have been recorded. Because the available biochemical information was derived mostly from disrupted and fractionated liver cells, it seemed desirable to examine the problem with the techniques of electron microscopy in order to see what changes are apparent in the intact liver cell after hypophysectomy. Accordingly, liver cells from rats which had been hypophysectomized 5-120 days before sacrifice were studied. Sham-operated rats served as controls and both hypophysectomized and control rats were fasted 15 hours before sacrifice.


1992 ◽  
Vol 44 (4) ◽  
pp. 827-829 ◽  
Author(s):  
Rolf Gaustad ◽  
Trond Berg ◽  
Frode Fonnum

1988 ◽  
Vol 263 (5) ◽  
pp. 2299-2303 ◽  
Author(s):  
L Combettes ◽  
M Dumont ◽  
B Berthon ◽  
S Erlinger ◽  
M Claret

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