A Facile Synthesis of 4,6,7,8,8a,9-Hexahydropyrrolo[1,2-a][1,2,3]triazolo[1,5-d]pyr­azines by a Three-Component Coupling Reaction Followed by Intramolecular 1,3-Dipolar Cycloaddition

2013 ◽  
Vol 2013 (19) ◽  
pp. 4119-4130 ◽  
Author(s):  
Attrimuni P. Dhondge ◽  
Shakil N. Afraj ◽  
Cut Nuzlia ◽  
Chinpiao Chen ◽  
Gene-Hsian Lee
Keyword(s):  
Coupling Reaction ◽  
Dipolar Cycloaddition ◽  
Facile Synthesis ◽  
Three Component Coupling

A bromine-radical mediated three-component reaction comprising allenes, electron-deficient alkenes and allyl bromides: facile synthesis of 2-bromo-1,7-dienes

2014 ◽  
Vol 50 (45) ◽  
pp. 5993-5996 ◽  
Author(s):  
Takashi Kippo ◽  
Ilhyong Ryu
Keyword(s):  
Coupling Reaction ◽  
Facile Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Three Component Coupling

A bromine-radical mediated three-component coupling reaction was effectively achieved by the use of allenes, electron-deficient alkenes, and allyl bromides and led to the synthesis of 2-bromo-1,7-dienes in good to high yields.

Facile Synthesis of (-)-Ascochlorin Using Palladium-Catalyzed Three Component Coupling Reaction.

ChemInform ◽  
2007 ◽  
Vol 38 (41) ◽  
Author(s):  
Makoto Aoki ◽  
Kenji Kawashima ◽  
Hirohisa Fujihara ◽  
Isao Shimizu
Keyword(s):  
Coupling Reaction ◽  
Facile Synthesis ◽  
Palladium Catalyzed ◽  
Three Component Coupling

Manganese(ii) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

RSC Advances ◽  
2014 ◽  
Vol 4 (50) ◽  
pp. 26301-26308 ◽  
Author(s):  
Shakil N. Afraj ◽  
Chinpiao Chen ◽  
Gene-Hsian Lee
Keyword(s):  
Efficient Method ◽  
Cycloaddition Reaction ◽  
Coupling Reaction ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Co Catalyst ◽  
Free Condition ◽  
Highly Efficient ◽  
Solvent Free Condition ◽  
Three Component Coupling

A one-pot green and highly efficient method for the synthesis of propargylamines and distereoselective synthesis of fused triazoles via three-component coupling in the presence of manganese(ii) chloride and a catalyst-free 1,3-dipolar cycloaddition reaction without using a co-catalyst is reported.

Facile Synthesis of (−)-Ascochlorin Using Palladium-catalyzed Three Component Coupling Reaction

2007 ◽  
Vol 36 (5) ◽  
pp. 654-655 ◽  
Author(s):  
Makoto Aoki ◽  
Kenji Kawashima ◽  
Hirohisa Fujihara ◽  
Isao Shimizu
Keyword(s):  
Coupling Reaction ◽  
Facile Synthesis ◽  
Palladium Catalyzed ◽  
Three Component Coupling

scholarly journals N-Alkylation/aldol reaction of α-aldimino thioesters: a facile three-component coupling reaction

RSC Advances ◽  
2021 ◽  
Vol 11 (22) ◽  
pp. 13097-13104
Author(s):  
Makoto Shimizu ◽  
Asako Higashino ◽  
Isao Mizota ◽  
Yusong Zhu
Keyword(s):  
Aldol Reaction ◽  
Coupling Reaction ◽  
Three Component Coupling

Treatment of α-aldimino thioesters with dialkylzinc reagents in the presence of aldehydes or imines gives three-component coupling products in good yields with good to high anti-selectivities.

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