scholarly journals The cancer stem cell model: B cell acute lymphoblastic leukaemia breaks the mould

2012 ◽  
Vol 5 (1) ◽  
pp. 7-9 ◽  
Author(s):  
James Scott McClellan ◽  
Ravindra Majeti
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Acute Lymphoblastic Leukaemia ◽  
B Cell ◽  
Lymphoblastic Leukaemia ◽  
Cell Model ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

Stem Cells in Acute Lymphoblastic Leukaemia

2012 ◽  
Vol 08 (03) ◽  
pp. 196
Author(s):  
Alex Elder ◽  
Olaf Heidenreich ◽  
Josef Vormoor ◽  
◽  
◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Cell Model ◽  
Cell Of Origin ◽  
Stem Cell Model ◽  
Stem Cell Populations ◽  
Stem Cell Models ◽  
Cancer Stem Cell Model

There has been significant debate over the identity of cancer stem cell populations in acute lymphoblastic leukaemia (ALL), with different groups reporting seemingly contradictory results. The latest findings suggest that tumour-propagating capacity is found within a high percentage of ALL blasts and that these cells have diverse immunophenotypes, which suggests that ALL follows a stochastic cancer stem cell model – as opposed to a hierarchical model. Recent data add a layer of complexity to the tumour evolution process by showing that the leukaemia-propagating compartment consists of multiple genetically diverse subclones related by Darwinian-style evolutionary trees. Differences in the cell of origin may also affect tumour development. In this article, we discuss the applicability of cancer stem cell models to ALL in the context of these recent findings.

scholarly journals A Cancer Stem Cell Model for Studying Brain Metastases From Primary Lung Cancer

2013 ◽  
Vol 105 (8) ◽  
pp. 551-562 ◽  
Author(s):  
Sara M. Nolte ◽  
Chitra Venugopal ◽  
Nicole McFarlane ◽  
Olena Morozova ◽  
Robin M. Hallett ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Stem Cell ◽  
Brain Metastases ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Primary Lung Cancer ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

scholarly journals Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show

2011 ◽  
Author(s):  
Md. Al Mamun ◽  
Md. Shaifur Rahman ◽  
Md. Fahmid Islam ◽  
Ummay Honi ◽  
Mahbub E. Sobhani
Keyword(s):  
Stem Cell ◽  
Molecular Biology ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Cancer Initiation ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

From the conventional Bird’s eye, cancer initiation and metastasis are generally intended to be understood beneath the light of classical clonal genetic, epigenetic and cancer stem cell model. But inspite decades of investigation, molecular biology has shown hard success to give Eagle’s eye in unraveling the riddle of cancer. And it seems, tiring Tom runs in vague behind naughty Jerry.

scholarly journals Evolution of the Cancer Stem Cell Model

2014 ◽  
Vol 14 (3) ◽  
pp. 275-291 ◽  
Author(s):  
Antonija Kreso ◽  
John E. Dick
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

Abstract 418: Development and characterization of cancer stem cell model from mouse iPS cells

2012 ◽  
Author(s):  
Ling Chen ◽  
Shuichi Matsuda ◽  
Tomonari Kasai ◽  
Yuh Sugii ◽  
Masashi Okada ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Ips Cells ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

Establishing a Colon Cancer Stem Cell Model to Study Tumor Chemoresistance

2012 ◽  
Vol 172 (2) ◽  
pp. 193
Author(s):  
A.M. Jarrar ◽  
F. Lotti ◽  
K. Sukhedo ◽  
J. Rich ◽  
M. Kalady
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Colon Cancer Stem Cell ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model

A Cancer Stem Cell Model

2014 ◽  
pp. 79-87
Author(s):  
Akifumi Mizutani ◽  
Ling Chen ◽  
Tomonari Kasai ◽  
Takayuki Kudoh ◽  
Hiroshi Murakami ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Model ◽  
Stem Cell Model ◽  
Cancer Stem Cell Model
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