Thyroid carcinoma presenting as a regional neck mass

Background: Thyroid cancer is fairly common. The worldwide annual incidence ranges from 0.5 to 10 cases per 100,000 people. Anaplastic thyroid carcinoma, comprising less than 10% of all thyroid carcinomas, remains one of the most virulent of all cancers in humans with a 10 year survival rate of only 0.1 %. In the present study we looked into the clinical, cytological and histological spectrum of anaplastic carcinoma and compared our experience with recent literature. Materials and Methods: This was a hospital based retrospective study from January 2000 to November 2010. Clinical, cytological and histopathological data of all the diagnosed anaplastic thyroid carcinoma cases were reviewed and analyzed. Results: Of the 59 thyroid malignancies diagnosed in the same period, 7 cases were anaplastic carcinoma. The mean age was 63 years and was predominantly found in females. All of the cases presented with a neck mass that lasted for a mean of 5.7 months. The mean tumor size was 14.9 cm and the most common sub-type was the spindle cell type. Atypical mitosis of more than 5 per high power field and necrosis was noted in all cases. Conclusion: Due to the markedly aggressive nature of this tumor and its association with areas of endemic thyroid disease, early diagnosis and aggressive therapy is essential, especially in the Himalayan and Sub-Himalayan belt. Keywords: Anaplastic carcinoma; Thyroid carcinoma; Spindle cell variant DOI: 10.3126/jpn.v1i1.4451 Journal of Pathology of Nepal (2011) Vol.1, 45-48

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Cystic lateral neck mass: Papillary thyroid carcinoma metastases with concomitant lymphangioma

Journal of Dr NTR University of Health Sciences ◽

10.4103/jdrntruhs.jdrntruhs_99_19 ◽

2019 ◽

Vol 8 (4) ◽

pp. 261

Author(s):

InugantiVenkata Renuka ◽

Chitturi Ramya ◽

Sripriya Krishnan ◽

SowjanyaKrishna Sree Kesaboyina

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Neck Mass ◽

Lateral Neck ◽

Papillary Thyroid

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A Case Report Demonstrating How the Clinical Presentation of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Can Mimic Benign Riedel’s Thyroiditis

Case Reports in Endocrinology ◽

10.1155/2015/686085 ◽

2015 ◽

Vol 2015 ◽

pp. 1-3

Author(s):

Jennifer Walsh ◽

Tomas P. Griffin ◽

Carmel B. Ryan ◽

James Fitzgibbon ◽

Patrick Sheahan ◽

...

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Lymph Nodes ◽

Inflammatory Cells ◽

Needle Aspiration ◽

Neck Mass ◽

Papillary Thyroid ◽

Riedel’S Thyroiditis ◽

Diffuse Sclerosing Variant ◽

Riedel's Thyroiditis

A 44-year-old female presented with a two-month history of a neck mass, sore throat, hoarseness, and intermittent dysphagia. Examination revealed a “woody” hard swelling arising from the right lobe of the thyroid. Clinically this was felt to be classical Riedel’s thyroiditis (RT). Thyroid ultrasound showed a diffusely enlarged, low echogenicity thyroid with a multinodular goitre. An abnormal nodule extending across the isthmus was noted. Following a nondiagnostic fine needle aspiration, an open core biopsy was performed. This showed dense sclerotic fibrosis punctuated by nodular mononuclear inflammatory cells, which obscured follicular epithelial cells consistent with a fibrosing thyroiditis (Riedel’s thyroiditis). A biopsy of pretracheal lymph nodes showed a sclerotic process throughout the lymph nodes and nests of epithelium bands with squamous differentiation obscured by a fibrous process. These findings raised the differential diagnosis of diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) with metastasis to lymph nodes. A total thyroidectomy and pretracheal lymph node dissection were performed. The final histological diagnosis was DSV-PTC. When managing a patient with presumed RT it is important to consider malignancy in the differential. DSV-PTC is one of the more aggressive forms of thyroid cancer but with early diagnosis and appropriate treatment patients may have excellent outcomes.

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Long-Standing Lateral Neck Mass As the Initial Manifestation of Well-Differentiated Thyroid Carcinoma

The Laryngoscope ◽

10.1097/00005537-200002010-00004 ◽

2000 ◽

Vol 110 (2) ◽

pp. 204-204 ◽

Cited By ~ 16

Author(s):

Sean C. Coleman ◽

Jonathan C. Smith ◽

Brian B. Burkey ◽

Terrence A. Day ◽

Robert N. Page ◽

...

Keyword(s):

Thyroid Carcinoma ◽

Differentiated Thyroid Carcinoma ◽

Neck Mass ◽

Lateral Neck ◽

Initial Manifestation ◽

Well Differentiated

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Extensive Neck Haematoma as an Extremely Rare Presentation of Thyroid Carcinoma: A Case Report

International Journal of Human and Health Sciences (IJHHS) ◽

10.31344/ijhhs.v4i3.205 ◽

2020 ◽

Vol 4 (3) ◽

pp. 226

Author(s):

Lo Ren Hui ◽

Fairuz Mohd Ibrahim ◽

Khairudin Abdullah ◽

Nasriah Ahmad ◽

Fazilah Hassan ◽

...

Keyword(s):

Case Report ◽

Thyroid Carcinoma ◽

Airway Obstruction ◽

Upper Airway ◽

Health Sciences ◽

Neck Mass ◽

Anaplastic Thyroid Carcinoma ◽

Upper Airway Obstruction ◽

Rare Presentation ◽

Fast Growing

Anaplastic thyroid carcinoma (ATC) is uncommon but deadly. It is typically presented with fast growing neck mass, hoarseness or dysphagia. We report an extremely rare presentation of ATC in an elderly lady, with expanding ecchymosis involving laryngopharynx, neck and upper chest region, which causing upper airway obstruction. The rarity of presentation and the management dilemma were discussed.International Journal of Human and Health Sciences Vol. 04 No. 03 July’20 Page : 226-228

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Cystic lateral neck mass: Thyroid carcinoma metastasis to branchial cleft cyst

Journal of Cancer Research and Therapeutics ◽

10.4103/0973-1482.188440 ◽

2018 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Gokhan Tazegul ◽

Hümeyra Bozoğlan ◽

Özlem Doğan ◽

Ramazan Sari ◽

HasanAli Altunbaş ◽

...

Keyword(s):

Thyroid Carcinoma ◽

Neck Mass ◽

Lateral Neck ◽

Branchial Cleft Cyst ◽

Branchial Cleft ◽

Carcinoma Metastasis

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Occult Thyroid Carcinoma Manifested as a Cystic Neck Mass

Southern Medical Journal ◽

10.1097/00007611-199710000-00010 ◽

1997 ◽

Vol 90 (10) ◽

pp. 1027-1028 ◽

Cited By ~ 1

Author(s):

JAMES H. NORTH

Keyword(s):

Thyroid Carcinoma ◽

Neck Mass ◽

Occult Thyroid Carcinoma

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Ocular metastasis from a rare thyroid carcinoma

Asian Journal of Ophthalmology ◽

10.35119/asjoo.v14i1.5 ◽

2014 ◽

Vol 14 (1) ◽

pp. 25-30

Author(s):

Archimedes Lee Agahan ◽

Ryner Jose Carrillo ◽

Peter Mark Chao ◽

Ramil Lising

Keyword(s):

Retinal Detachment ◽

Thyroid Carcinoma ◽

Radical Neck Dissection ◽

Vitreous Hemorrhage ◽

Abdominal Ultrasound ◽

Needle Aspiration ◽

Neck Mass ◽

Whole Body ◽

Ocular Ultrasound ◽

Computed Topography

Objective: To report a case of primary thyroid carcinoma with ocular metastasis.Methods: This is a case report of a 39-year-old male, who initially presented with a sudden painless loss of vision in the left eye and an anterior neck mass. He was initially diagnosed to have retinal detachment with vitreous hemorrhage based on ocular ultrasound. Fine Needle Aspiration Biopsy of the neck mass initially revealed medullary thyroid carcinoma. Computed topography of the chest and abdominal ultrasound revealed lung and liver metastasis. Whole body bone scintigraphy also revealed bone metastasis.Results: Patient underwent total thyroidectomy with bilateral modified radical neck dissection of the neck mass and vitreous biopsy of the left eye. Histopathology report revealed malignant carcinoma of the thyroid, medullary type while vitreous showed malignant cells from the thyroid. Patient was scheduled to undergo chemotherapy for the widespread metastasis.Conclusions: Ocular malignancy can present in many ways, thus it is necessary to consider it as a differential for cases of retinal detachment and vitreous hemorrhage. Choroidal metastasis from malignant thyroid carcinoma is rare, more so the medullary type.

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