Two cases of malignant thymoma presenting as an anterior neck mass and misdiagnosed as thyroid carcinoma

AbstractObjectivesWe aim to report a case of a fetal goiter with postpartum spontaneous resolution. Fetal goiter can be secondary to maternal treatment and range from clinically asymptomatic or cause alterations in the fetus, from impaired swallowing to difficulty in vaginal delivery and even perinatal asphyxia due to the mass effect. The need for intrauterine treatment remains controversial.Case presentationWe present a case of fetal goiter with postpartum resolution. A 34-year-old multigravida presented to the emergency department with hiperemesis gravidarum at 10 weeks’ gestation. During evaluation for severe vomiting, Graves disease was diagnosed and treated with propylthiouracil. A routine ultrasound scan at 28 weeks gestation revealed a fetal anterior neck mass suggesting a fetal goiter. Cordocentesis showed fetal iatrogenic hypothyroidism. Conservative treatment was decided. Pregnancy concluded uneventful and the mass resolved spontaneously in the newborn.ConclusionsThe fetal thyroid gland is a structure that usually goes unnoticed during the process of prenatal diagnosis. In cases of maternal Graves diseases, fetal thyroid needs monitoring during pregnancy and conservative treatment is an option. Fetal goiter should be searched for secondary to thyroid alterations of the gravida, and in selected cases it can be managed without intrauterine treatment.

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Mediastinal seminoma presenting as a neck mass falsely diagnosed as anaplastic thyroid carcinoma: A case report

Diagnostic Cytopathology ◽

10.1002/dc.24090 ◽

2018 ◽

Vol 47 (4) ◽

pp. 334-336 ◽

Cited By ~ 1

Author(s):

Khaled Murshed ◽

Issam Al-Bozom ◽

Surjith Vattoth ◽

Mohammed Akhtar

Keyword(s):

Case Report ◽

Thyroid Carcinoma ◽

Neck Mass ◽

Anaplastic Thyroid Carcinoma ◽

Mediastinal Seminoma

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Anaplastic carcinoma of the thyroid - clinicomorphological spectrum and review of literature

Journal of Pathology of Nepal ◽

10.3126/jpn.v1i1.4451 ◽

1970 ◽

Vol 1 (1) ◽

pp. 45-48 ◽

Cited By ~ 1

Author(s):

A Ghosh ◽

N Nepal ◽

MD Gharti ◽

S Basnet ◽

M Baxi ◽

...

Keyword(s):

Thyroid Carcinoma ◽

Spindle Cell ◽

Neck Mass ◽

Anaplastic Thyroid Carcinoma ◽

Anaplastic Carcinoma ◽

High Power Field ◽

The Mean ◽

Cell Variant ◽

Thyroid Malignancies ◽

Atypical Mitosis

Background: Thyroid cancer is fairly common. The worldwide annual incidence ranges from 0.5 to 10 cases per 100,000 people. Anaplastic thyroid carcinoma, comprising less than 10% of all thyroid carcinomas, remains one of the most virulent of all cancers in humans with a 10 year survival rate of only 0.1 %. In the present study we looked into the clinical, cytological and histological spectrum of anaplastic carcinoma and compared our experience with recent literature. Materials and Methods: This was a hospital based retrospective study from January 2000 to November 2010. Clinical, cytological and histopathological data of all the diagnosed anaplastic thyroid carcinoma cases were reviewed and analyzed. Results: Of the 59 thyroid malignancies diagnosed in the same period, 7 cases were anaplastic carcinoma. The mean age was 63 years and was predominantly found in females. All of the cases presented with a neck mass that lasted for a mean of 5.7 months. The mean tumor size was 14.9 cm and the most common sub-type was the spindle cell type. Atypical mitosis of more than 5 per high power field and necrosis was noted in all cases. Conclusion: Due to the markedly aggressive nature of this tumor and its association with areas of endemic thyroid disease, early diagnosis and aggressive therapy is essential, especially in the Himalayan and Sub-Himalayan belt. Keywords: Anaplastic carcinoma; Thyroid carcinoma; Spindle cell variant DOI: 10.3126/jpn.v1i1.4451 Journal of Pathology of Nepal (2011) Vol.1, 45-48

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Cystic lateral neck mass: Papillary thyroid carcinoma metastases with concomitant lymphangioma

Journal of Dr NTR University of Health Sciences ◽

10.4103/jdrntruhs.jdrntruhs_99_19 ◽

2019 ◽

Vol 8 (4) ◽

pp. 261

Author(s):

InugantiVenkata Renuka ◽

Chitturi Ramya ◽

Sripriya Krishnan ◽

SowjanyaKrishna Sree Kesaboyina

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Neck Mass ◽

Lateral Neck ◽

Papillary Thyroid

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Clinical Significance of Barium Swallow Fluoroscopy in Anterior Neck Mass Management

Dysphagia ◽

10.1007/s00455-021-10345-w ◽

2021 ◽

Author(s):

Yu-Hsuan Kuo ◽

Kuei-You Lin

Keyword(s):

Clinical Significance ◽

Neck Mass ◽

Barium Swallow ◽

Anterior Neck

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A Case Report Demonstrating How the Clinical Presentation of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Can Mimic Benign Riedel’s Thyroiditis

Case Reports in Endocrinology ◽

10.1155/2015/686085 ◽

2015 ◽

Vol 2015 ◽

pp. 1-3

Author(s):

Jennifer Walsh ◽

Tomas P. Griffin ◽

Carmel B. Ryan ◽

James Fitzgibbon ◽

Patrick Sheahan ◽

...

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Lymph Nodes ◽

Inflammatory Cells ◽

Needle Aspiration ◽

Neck Mass ◽

Papillary Thyroid ◽

Riedel’S Thyroiditis ◽

Diffuse Sclerosing Variant ◽

Riedel's Thyroiditis

A 44-year-old female presented with a two-month history of a neck mass, sore throat, hoarseness, and intermittent dysphagia. Examination revealed a “woody” hard swelling arising from the right lobe of the thyroid. Clinically this was felt to be classical Riedel’s thyroiditis (RT). Thyroid ultrasound showed a diffusely enlarged, low echogenicity thyroid with a multinodular goitre. An abnormal nodule extending across the isthmus was noted. Following a nondiagnostic fine needle aspiration, an open core biopsy was performed. This showed dense sclerotic fibrosis punctuated by nodular mononuclear inflammatory cells, which obscured follicular epithelial cells consistent with a fibrosing thyroiditis (Riedel’s thyroiditis). A biopsy of pretracheal lymph nodes showed a sclerotic process throughout the lymph nodes and nests of epithelium bands with squamous differentiation obscured by a fibrous process. These findings raised the differential diagnosis of diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) with metastasis to lymph nodes. A total thyroidectomy and pretracheal lymph node dissection were performed. The final histological diagnosis was DSV-PTC. When managing a patient with presumed RT it is important to consider malignancy in the differential. DSV-PTC is one of the more aggressive forms of thyroid cancer but with early diagnosis and appropriate treatment patients may have excellent outcomes.

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