Comparative study of acute effects of single doses of fexofenadine, olopatadine,d-chlorpheniramine and placebo on psychomotor function in healthy volunteers

2003 ◽  
Vol 18 (8) ◽  
pp. 611-618 ◽  
Author(s):  
Hiroyuki Kamei ◽  
Yukihiro Noda ◽  
Kazuhiro Ishikawa ◽  
Koji Senzaki ◽  
Isao Muraoka ◽  
...  
2018 ◽  
Vol 85 (2) ◽  
pp. 442-453 ◽  
Author(s):  
Maren Cecilie Strand ◽  
Vigdis Vindenes ◽  
Hallvard Gjerde ◽  
Jørg Gustav Mørland ◽  
Johannes G. Ramaekers

1989 ◽  
Vol 17 (1) ◽  
pp. 24-27 ◽  
Author(s):  
L. Ghys ◽  
J.-P. Rihoux

In a double-blind study performed in 81 healthy volunteers, 10 mg cetirizine and 60 mg terfenadine given orally in a single administration significantly inhibited skin reactivity to histamine. Astemizole (10 mg) was completely ineffective. The inhibitory effect of cetirizine was potent and regular whereas 6/28 (21%) volunteers did not respond to terfenadine. The difference observed beween cetirizine and terfenadine might be due to differences in the metabolism of the two drugs after administration: terfenadine is rapidly and extensively metabolized whereas cetirizine is directly active without the need for biotransformation and, indeed is poorly metabolized.


2017 ◽  
Vol 11 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Desiree Vrijens ◽  
Tom Marcelissen ◽  
Jamie Drossaerts ◽  
Rhea Heeringa ◽  
Sam Degaillier ◽  
...  

1998 ◽  
Vol 23 (2) ◽  
pp. 189-196 ◽  
Author(s):  
K Antoniou ◽  
E Kafetzopoulos ◽  
Z Papadopoulou-Daifoti ◽  
T Hyphantis ◽  
M Marselos

Cough ◽  
2014 ◽  
Vol 10 (1) ◽  
Author(s):  
Federico Lavorini ◽  
Elisa Chellini ◽  
Margherita Innocenti ◽  
Giacomo Campi ◽  
Colin Gerard Egan ◽  
...  

EBioMedicine ◽  
2020 ◽  
Vol 54 ◽  
pp. 102712
Author(s):  
Uli Niemann ◽  
Myra Spiliopoulou ◽  
Jan Malanowski ◽  
Juliane Kellersmann ◽  
Thorsten Szczepanski ◽  
...  

2004 ◽  
Vol 36 (05) ◽  
pp. 181-186 ◽  
Author(s):  
T. Gunnarsson ◽  
C. Mahoney ◽  
J. Shlik ◽  
J. Bradwejn ◽  
V. Knott

1985 ◽  
Vol 39 ◽  
pp. 157
Author(s):  
Naoko Hino ◽  
Akio Fujimura ◽  
Akio Ebihara ◽  
Kyoichi Ohashi ◽  
Kazuoki Kondo

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