The influence of the route of administration of nitrogen mustard and melphalan upon their anti-tumour activity in the rat

1966 ◽  
Vol 1 (4) ◽  
pp. 329-336 ◽  
Author(s):  
L. M. Cobb
Keyword(s):  
Nitrogen Mustard ◽  
Route Of Administration ◽  
Anti Tumour Activity ◽  
Tumour Activity

Anti-mesodermal Activity of a Nitrogen Mustard Derivative

Development ◽  
1963 ◽  
Vol 11 (4) ◽  
pp. 689-696
Author(s):  
A. Jurand
Keyword(s):  
Nitrogen Mustard ◽  
Saline Solution ◽  
Embryonic Tissues ◽  
Anti Tumour Activity ◽  
Stage 4 ◽  
Cent Saline ◽  
Specific Selectivity ◽  
Walker Carcinoma ◽  
Derivatives Of ◽  
Tumour Activity

Amongst the numerous derivatives of nitrogen mustard that have been tested for their anti-tumour activity on Walker carcinoma by Danielli and his collaborators (1961), (Cl—CH2—CH2)2: N—C6H4—O—CO—NH—C6H4—COOH, i.e., p-(NN-Di-2-chloroethyloamino)-phenyl- N-(p-carboxyphenyl) - carbamate (later referred to as I.C. 140), has been found to be particularly promising. To check its cytotoxic activity for embryos, and to find out, if possible, whether I.C. 140 has any specific selectivity for particular embryonic tissues, chick and mouse embryos were treated during the early stages of development. Chick embryos were explanted according to the method described by New (1955) at Stage 4 or 5 (Hamburger & Hamilton, 1955), i.e., after a pre-incubation period of 22 hr. As I.C. 140 is difficult to dissolve in water, it was first suspended in an appropriate volume of 0·9 per cent, saline solution. One part of this suspension was then diluted with nine parts of liquid albumen to give the final concentration of 50 or 100 μg. per ml.

Synthesis and Anti – Tumour Activity of Novel Camptothecin – Bile Acid Analogues

2011 ◽  
Vol 8 (8) ◽  
pp. 698-703 ◽  
Author(s):  
Q.-Y. Li ◽  
Y. Gao ◽  
W. Qiu ◽  
Y.-G. Zu ◽  
L. Su ◽  
...  
Keyword(s):  
Bile Acid ◽  
Anti Tumour Activity ◽  
Tumour Activity

scholarly journals Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure

2019 ◽  
Vol 52 (5) ◽  
Author(s):  
Xueping Xie ◽  
Yuxin Zhang ◽  
Wenjuan Ma ◽  
Xiaoru Shao ◽  
Yuxi Zhan ◽  
...  
Keyword(s):  
Dna Nanostructure ◽  
Anti Tumour Activity ◽  
Tumour Activity

Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma

2010 ◽  
Vol 46 (18) ◽  
pp. 3251-3262 ◽  
Author(s):  
Birgit Geoerger ◽  
Jean-François Brasme ◽  
Estelle Daudigeos-Dubus ◽  
Paule Opolon ◽  
Corinne Venot ◽  
...  
Keyword(s):  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Receptor Antibody ◽  
Anti Tumour Activity ◽  
Tumour Activity

New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins

2013 ◽  
Vol 394 ◽  
pp. 616-626 ◽  
Author(s):  
Cristina P. Matos ◽  
Andreia Valente ◽  
Fernanda Marques ◽  
Pedro Adão ◽  
M. Paula Robalo ◽  
...  
Keyword(s):  
Human Serum ◽  
Serum Proteins ◽  
Anti Tumour Activity ◽  
Tumour Activity ◽  
Human Serum Proteins

Anti-tumour activity of a panel of taxanes toward a cellular model of human cervical cancer

2000 ◽  
Vol 45 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Daniela Gallo ◽  
Cristiano Ferlini ◽  
Mariagrazia Distefano ◽  
Fabio Cantelmo ◽  
Cristiana Gaggini ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cellular Model ◽  
Anti Tumour Activity ◽  
Tumour Activity ◽  
Human Cervical Cancer
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