Expression on cultured human tumour cells of placental trophoblast membrane antigens and placental alkaline phosphatase defined by monoclonal antibodies

1982 ◽  
Vol 30 (1) ◽  
pp. 21-26 ◽  
Author(s):  
P. J. McLaughlin ◽  
M. H. Cheng ◽  
M. B. Slade ◽  
P. M. Johnson
2018 ◽  
Vol 2 (12) ◽  
pp. 915-929 ◽  
Author(s):  
Ryan A. Carpenter ◽  
Jun-Goo Kwak ◽  
Shelly R. Peyton ◽  
Jungwoo Lee

Nature ◽  
1982 ◽  
Vol 297 (5863) ◽  
pp. 234-236 ◽  
Author(s):  
Charles B. Simone

2001 ◽  
Vol 85 (10) ◽  
pp. 1585-1591 ◽  
Author(s):  
H U Barthelmes ◽  
E Niederberger ◽  
T Roth ◽  
K Schulte ◽  
W C Tang ◽  
...  

1983 ◽  
Vol 29 (1) ◽  
pp. 115-119 ◽  
Author(s):  
G De Groote ◽  
P De Waele ◽  
A Van de Voorde ◽  
M De Broe ◽  
W Fiers

Abstract Convenient, sensitive, and specific solid-phase immunoassays involving monoclonal antibody are described for the determination of human placental alkaline phosphatase (hPLAP). An endogenous enzyme immunoassay combined the specificity of the immunological and the enzymatic reactions. Alternatively, a solid-phase "sandwich" radioimmunoassay involving immobilized polyclonal rabbit anti-hPLAP in combination with iodinated monoclonal antibody provided some additional advantages. Both tests can be used to detect hPLAP from various sources, e.g., in human sera during pregnancy or as a tumor marker. The radioimmunoassay detected an increase in hPLAP at nine weeks of gestation. We discuss the use of monoclonal antibodies for the differentiation of different alkaline phosphatase isoenzyme types by electrophoresis on starch gel.


1982 ◽  
Vol 52 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Martin Körbling ◽  
Allan D. Hess ◽  
Peter J. Tutschka ◽  
Herbert Kaizer ◽  
Michael O. Colvin ◽  
...  

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