Expression of galectin-1 in normal human thyroid gland and in differentiated and poorly differentiated thyroid tumors

1995 ◽  
Vol 64 (3) ◽  
pp. 171-175 ◽  
Author(s):  
Lorenzo Chiariotti ◽  
Maria Teresa Berlingieri ◽  
Caterina Battaglia ◽  
Giovanna Benvenuto ◽  
Maria Luisa Martelli ◽  
...  
1974 ◽  
Vol 4 (1) ◽  
pp. 65-69 ◽  
Author(s):  
H. Bürgi ◽  
M. Benguerel ◽  
J. Knopp ◽  
H. Kohler ◽  
H. Studer

1977 ◽  
Vol 84 (2) ◽  
pp. 281-289 ◽  
Author(s):  
U. Westgren ◽  
A. Melander ◽  
S. Ingemansson ◽  
A. Burger ◽  
S. Tibblin ◽  
...  

ABSTRACT The secretion of iodothyronines from the normal human thyroid gland was assessed by radioimmunoassay analyses of the concentrations of thyroxine (T4), 3,5,3′-triiodothyronine (T3) and 3,3′,5′-triiodothyronine (reverse T3, rT3) in thyroid venous and peripheral venous blood. The subjects studied were euthyroid patients undergoing parathyroid surgery. Measurements were carried out both under apparently normal conditions, following peroral T3 pre-treatment, and before and after acute administration of TSH into a thyroid artery. In the control subjects, significant gradients between thyroid venous and peripheral venous concentrations were recorded both for T4, T3 and rT3, suggesting that all three iodothyronines are secreted by the normal human thyroid. T3 pre-treatment seemed to reduce this secretion, and acute administration of TSH promoted rapid, marked, and concomitant increments in the thyroid venous concentrations of all three iodothyronines. Hence, it appears that not only T4 but also T3 and rT3 are secreted by the normal human thyroid gland, and that TSH stimulates the secretion of all three iodothyronines. On the other hand, calculations of the relative secretion rates yielded the relation T4:T3:rT3 as 85:9:1. This indicates that, in euthyroid subjects, most of T3, and almost all of rT3, is produced by extrathyroidal conversion of T4 and not by direct thyroidal secretion.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Soledad Cameselle‑García ◽  
Sámer Abdulkader‑Sande ◽  
María Sánchez‑Ares ◽  
Gemma Rodríguez‑carnero ◽  
Jesús Garcia‑Gómez ◽  
...  

Author(s):  
N. P. Dmitrieva

One of the most characteristic features of cancer cells is their ability to metastasia. It is suggested that the modifications of the structure and properties of cancer cells surfaces play the main role in this process. The present work was aimed at finding out what ultrastructural features apear in tumor in vivo which removal of individual cancer cells from the cell population can provide. For this purpose the cellular interactions in the normal human thyroid and cancer tumor of this gland electron microscopic were studied. The tissues were fixed in osmium tetroxide and were embedded in Araldite-Epon.In normal human thyroid the most common type of intercellular contacts was represented by simple junction formed by the parallelalignment of adjacent cell membranees leaving in between an intermembranes space 15-20 nm filled with electronlucid material (Fig. 1a). Sometimes in the basal part of cells dilatations of the intercellular space 40-50 nm wide were found (Fig. 1a). Here the cell surfaces may form single short microvilli.


2013 ◽  
Vol 1 (2) ◽  
pp. 17-20
Author(s):  
Md Enayet Ullah ◽  
Hasna Hena ◽  
Rubina Qasim

Deep cervical fascia forms a connective tissue sheath around the thyroid gland. Delicate trabeculae and septa penetrate the gland indistinctly dividing the gland into lobes and lobules which in turn composed of follicles.1,2,3 These follicles are structural units of thyroid gland which varies greatly in size and shape.4 The number of follicles varies in different age groups. The study was carried out to see the percentage of area occupied by follicles in the stained section of thyroid glands in different age groups. The collected samples were grouped as A (3.5 – 20yrs), B (21- 40yrs) & C (41 – 78yrs). Percentage of area occupied by follicles was (58.55±10.72) in group A, (63.79±12.35) in group B + (63.39±8.29) in group C.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13981 Update Dent. Coll. j. 2011: 1(2): 17-20


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