scholarly journals Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans.

1993 ◽  
Vol 12 (6) ◽  
pp. 2329-2336 ◽  
Author(s):  
S. Takeda ◽  
Y.R. Zou ◽  
H. Bluethmann ◽  
D. Kitamura ◽  
U. Muller ◽  
...  
1991 ◽  
Vol 173 (2) ◽  
pp. 409-415 ◽  
Author(s):  
K Harada ◽  
H Yamagishi

Circular DNAs excised by immunoglobulin kappa chain gene rearrangements were cloned and characterized. 16 of 17 clones examined were double recombination products containing a V kappa-J kappa rearrangement (coding joint) as well as the reciprocal element (signal joint) of another V kappa-J kappa rearrangement. These products suggested multiple recombination, primary inversion, and secondary excision. In primary events, 5 of 16 translational reading frames were in-phase. Thus, V kappa gene rearrangement may not be inhibited by the presence of a productively rearranged allele. An unusually large trinucleotide (P) insertion forming a palindrome of 12 nucleotides was also observed in one of the coding joints.


1986 ◽  
Vol 78 (6) ◽  
pp. 1439-1442 ◽  
Author(s):  
K Ha-Kawa ◽  
J Hara ◽  
Y Keiko ◽  
A Muraguchi ◽  
N Kawamura ◽  
...  

1986 ◽  
Vol 83 (11) ◽  
pp. 3738-3742 ◽  
Author(s):  
S. Y. Huang ◽  
M. B. Barnard ◽  
M. Xu ◽  
S. Matsui ◽  
S. M. Rose ◽  
...  

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