scholarly journals Novel method for early signs of clinical shock detection by monitoring blood capillary/vessel spatial pattern

2013 ◽  
Vol 7 (10) ◽  
pp. 841-849 ◽  
Author(s):  
Rajesh Kanawade ◽  
Florian Klämpfl ◽  
Max Riemann ◽  
Christian Knipfer ◽  
Katja Tangermann-Gerk ◽  
...  
2012 ◽  
Vol 05 (02) ◽  
pp. 1250005 ◽  
Author(s):  
GUENNADI SAIKO ◽  
ALEXANDRE DOUPLIK

We developed a novel method for real-time monitoring of alteration of the local epithelium vessel/capillary and blood oxygenation spatial pattern in epithelium exploiting a compact fibre sensor system based on spatially and spectrally resolved diffuse reflectance. The method is based on collection of spatially resolved diffuse reflectance R(λ) by fiber sensors. The spatial resolution is provided as a dependence of R(λ) on a set of distances ρ between the source and detector (attenuation curve). It is expected that the new method can reasonably extract the minor spatial deviations of oxygenation and local blood volume fraction — parameters, directly related to the local vessel density and capillary spatial patterns in the epithelium. Light scattering in visible range is naturally taken into account in the proposed method.


JAMA ◽  
1966 ◽  
Vol 195 (1) ◽  
pp. 47-48
Author(s):  
A. L. Matles

Author(s):  
Robert Corbett ◽  
Delbert E. Philpott ◽  
Sam Black

Observation of subtle or early signs of change in spaceflight induced alterations on living systems require precise methods of sampling. In-flight analysis would be preferable but constraints of time, equipment, personnel and cost dictate the necessity for prolonged storage before retrieval. Because of this, various tissues have been stored in fixatives and combinations of fixatives and observed at various time intervals. High pressure and the effect of buffer alone have also been tried.Of the various tissues embedded, muscle, cartilage and liver, liver has been the most extensively studied because it contains large numbers of organelles common to all tissues (Fig. 1).


Author(s):  
M.A. Gregory ◽  
G.P. Hadley

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.


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