scholarly journals Inside Cover: A noninvasive imaging and measurement using optical coherence tomography angiography for the assessment of gingiva: An in vivo study (J. Biophotonics 12/2018)

2018 ◽  
Vol 11 (12) ◽  
pp. e201870173
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Noninvasive Imaging ◽  
In Vivo Study ◽  
Optical Coherence

A noninvasive imaging and measurement using optical coherence tomography angiography for the assessment of gingiva: An in vivo study

2018 ◽  
Vol 11 (12) ◽  
pp. e201800242 ◽  
Author(s):  
Nhan M. Le ◽  
Shaozhen Song ◽  
Hao Zhou ◽  
Jingjiang Xu ◽  
Yuandong Li ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Noninvasive Imaging ◽  
In Vivo Study ◽  
Optical Coherence

scholarly journals Evaluating Retinal and Choroidal Perfusion Changes after Isometric and Dynamic Activity Using Optical Coherence Tomography Angiography

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 808
Author(s):  
Max Philipp Brinkmann ◽  
Nikolas Xavier Kibele ◽  
Michelle Prasuhn ◽  
Vinodh Kakkassery ◽  
Mario Damiano Toro ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Isometric Exercise ◽  
Dynamic Exercise ◽  
Exercise Heart Rate ◽  
Optical Coherence ◽  
Dynamic Activity ◽  
Capillary Plexus ◽  
Choroidal Perfusion

Optical coherence tomography angiography (OCTA) is a non-invasive tool for imaging and quantifying the retinal and choroidal perfusion state in vivo. This study aimed to evaluate the acute effects of isometric and dynamic exercise on retinal and choroidal sublayer perfusion using OCTA. A pilot study was conducted on young, healthy participants, each of whom performed a specific isometric exercise on the first day and a dynamic exercise the day after. At baseline and immediately after the exercise, heart rate (HR), mean arterial pressure (MAP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattlers’s layer perfusion (SLP), and Haller’s layer perfusion (HLP) were recorded. A total of 34 eyes of 34 subjects with a mean age of 32.35 ± 7.87 years were included. HR as well as MAP increased significantly after both types of exercise. Both SCPP and DCPP did not show any significant alteration due to isometric or dynamic exercise. After performing dynamic exercise, CCP, SLP, as well as HLP significantly increased. Changes in MAP correlated significantly with changes in HLP after the dynamic activity. OCTA-based analysis in healthy adults following physical activity demonstrated a constant retinal perfusion, supporting the theory of autoregulatory mechanisms. Dynamic exercise, as opposed to isometric activity, significantly changed choroidal perfusion. OCTA imaging may represent a novel and sensitive tool to expand the diagnostic spectrum in the field of sports medicine.

scholarly journals A practical guide to optical coherence tomography angiography interpretation

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Eugenia Custo Greig ◽  
Jay S. Duker ◽  
Nadia K. Waheed
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Image Interpretation ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Clinical Practices ◽  
Imaging Device ◽  
Age Related ◽  
Retinal Microvasculature

Abstract Background Optical coherence tomography angiography (OCTA) can image the retinal vasculature in vivo, without the need for contrast dye. This technology has been commercially available since 2014, however, much of its use has been limited to the research setting. Over time, more clinical practices have adopted OCTA imaging. While countless publications detail OCTA’s use for the study of retinal microvasculature, few studies outline OCTA’s clinical utility. Body This review provides an overview of OCTA imaging and details tips for successful interpretation. The review begins with a summary of OCTA technology and artifacts that arise from image acquisition. New methods and best practices to prevent image artifacts are discussed. OCTA has the unique ability among retinovascular imaging modalities to individually visualize each retinal plexus. Slabs offered in standard OCTA devices are reviewed, and clinical uses for each slab are outlined. Lastly, the use of OCTA for the clinical interpretation of retinal pathology, such as diabetic retinopathy and age-related macular degeneration, is discussed. Conclusion OCTA is evolving from a scientific tool to a clinical imaging device. This review provides a toolkit for successful image interpretation in a clinical setting.

scholarly journals The vascular morphology of melanoma is related to Breslow index: An in vivo study with dynamic optical coherence tomography

2018 ◽  
Vol 27 (11) ◽  
pp. 1280-1286 ◽  
Author(s):  
Nathalie De Carvalho ◽  
Julia Welzel ◽  
Sandra Schuh ◽  
Lotte Themstrup ◽  
Martina Ulrich ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Study ◽  
Optical Coherence ◽  
Vascular Morphology ◽  
Breslow Index

In vivo study of contrasting properties of gold nanoparticles for optical coherence tomography

2007 ◽  
Author(s):  
E. V. Zagaynova ◽  
M. V. Shirmanova ◽  
A. G. Orlova ◽  
I. V. Balalaeva ◽  
M. Y. Kirillin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Coherence Tomography ◽  
In Vivo Study ◽  
Optical Coherence

scholarly journals Quantitative assessment of choriocapillaris flow deficits in diabetic retinopathy: A swept-source optical coherence tomography angiography study

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243830
Author(s):  
Yining Dai ◽  
Hao Zhou ◽  
Qinqin Zhang ◽  
Zhongdi Chu ◽  
Lisa C. Olmos de Koo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Healthy Subjects ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Swept Source ◽  
Significant Difference ◽  
En Face ◽  
The Mean

Purpose To quantitatively assess choriocapillaris (CC) flow deficits in eyes with diabetic retinopathy (DR) using swept-source optical coherence tomography angiography (SS-OCTA). Methods Diabetic subjects with different stages of DR and age-matched healthy subjects were recruited and imaged with SS-OCTA. The en face CC blood flow images were generated using previously published and validated algorithms. The percentage of CC flow deficits (FD%) and the mean CC flow deficit size were calculated in a 5-mm-diameter circle centered on the fovea from the 6×6-mm scans. Results Forty-five diabetic subjects and 27 control subjects were included in the study. The CC FD% in diabetic eyes was on average 1.4-fold greater than in control eyes (12.34±4.14% vs 8.82±2.61%, P < 0.001). The mean CC FD size in diabetic eyes was on average 1.4-fold larger than in control eyes (2151.3± 650.8μm2 vs 1574.4±255.0 μm2, P < 0.001). No significant difference in CC FD% or mean CC FD size was observed between eyes with nonproliferative DR and eyes with proliferative DR (P = 1.000 and P = 1.000, respectively). Conclusions CC perfusion in DR can be objectively and quantitatively assessed with FD% and FD size. In the macular region, both CC FD% and CC FD size are increased in eyes with DR. SS-OCTA provides new insights for the investigations of CC perfusion status in diabetes in vivo.

scholarly journals Optical Coherence Tomography Angiography of Early Stage 1a Retinal Hemangioblastoma in Von-Hippel-Lindau

2021 ◽  
Vol 8 (3) ◽  
pp. 15-18
Author(s):  
Ananya Goswami ◽  
Abhidnya Surve ◽  
Pradeep Venkatesh
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Early Stage ◽  
Optical Coherence ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Capillary Plexus ◽  
Retinal Hemangioblastoma ◽  
Retinal Capillaries

Von-Hippel-Lindau (VHL) syndrome is characterized by focal vasoproliferative tumors of retinal capillaries called retinal capillary hemangio-blastomas (RCH). These tumors are initially small and can be easily missed if not looked for carefully. As they grow, these tumors are more demanding to treat and hence the importance of detecting them early and treating them. Herein, we describe and review the optical coherence tomography angiography (OCTA) of the early-stage lesion, which suggested the involvement of superficial and a deeper retinal capillary plexus. In addition, to helping us detect these lesions earlier, OCTA may also help to understand the in vivo changes occurring at an earlier phase.

A comparative in-vivo study of the female urethra with cross-polarization optical coherence tomography using two types of endoscopic probes

2021 ◽  
Author(s):  
Elena B. Kiseleva ◽  
Pavel A. Shilyagin ◽  
Vasily V. Vlasov ◽  
Anton S. Kuyarov ◽  
Muhammat A. Molvi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Study ◽  
Optical Coherence ◽  
Cross Polarization ◽  
Female Urethra

Optical coherence tomography angiography in amblyopia: A critical update on current understandings and future perspectives

2021 ◽  
pp. 112067212110425
Author(s):  
Amar Pujari ◽  
Gunjan Saluja ◽  
Rohan Chawla ◽  
Asha Samdani ◽  
Swati Phuljhele ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Small Sample Size ◽  
Small Sample ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Patient Profile ◽  
Age Related ◽  
Choroidal Vasculature

Optical coherence tomography angiography (OCTA) is a non-invasive tool to assess the retino-choroidal vasculature in vivo. It tracks the red blood cell movement and maps the vasculature in quick succession. In routine, diabetic retinopathy, age related macular degeneration, central serous chorioretinopathy, and others are commonly being studied to unveil its clinic role. On the other hand, amblyopia is a condition where the visual acuity is subnormal due to non-organic causes in the eye. But the OCTA studies till now have shown variable changes along retino-choroidal vasculature. Hence, to comprehend the existing literature knowledge, a systematic literature search was carried out and the original works describing novel findings in amblyopic eyes on OCTA were included. Upon detailed assessment, firstly, the disturbed vasculature along superficial retinal plexus, deeper retinal plexus, and choroidal plexus were evident in most untreated amblyopic eyes. However, such changes were not uniform, which is due to noted heterogenic patient profile, small sample size, biometric biases, non-uniform algorithms, and other factors. And to note, even in presence of such diverse changes, almost all the authors stated a plausible explanation for their notable changes. Secondly, the utility of OCTA in identifying vascular changes with standard treatments and segregation of visual beneficiaries from non-beneficiaries were possible. Hence, to conclude, OCTA is a valuable tool which can provide valuable useful insights into the amblyopic eyes during pre and post treatment periods. However, to gather more concrete evidence for clinical benefits, systematic, homogenous, and better structured clinical studies are mandated.

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