Pulmonary function study of myasthenia-gravis patients treated with double-filtration plasmapheresis

2003 ◽  
Vol 18 (3) ◽  
pp. 125-128 ◽  
Author(s):  
Hou-Chang Chiu ◽  
Jiann-Horng Yeh ◽  
Wei-Hung Chen
Keyword(s):  
Pulmonary Function ◽  
Myasthenia Gravis ◽  
Function Study ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration

Treatment of refractory myasthenia gravis by double‐filtration plasmapheresis and rituximab: A case series of nine patients and literature review

2020 ◽  
Author(s):  
Hamza N. Bennani ◽  
Emmeline Lagrange ◽  
Johan Noble ◽  
Paolo Malvezzi ◽  
Lionel Motte ◽  
...  
Keyword(s):  
Literature Review ◽  
Myasthenia Gravis ◽  
Case Series ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration

Double filtration plasmapheresis benefits myasthenia gravis patients through an immunomodulatory action

2014 ◽  
Vol 21 (9) ◽  
pp. 1570-1574 ◽  
Author(s):  
Lei Zhang ◽  
Junfeng Liu ◽  
Hongna Wang ◽  
Chongbo Zhao ◽  
Jiahong Lu ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Double Filtration Plasmapheresis ◽  
Immunomodulatory Action ◽  
Double Filtration

scholarly journals Immunoglobulin versus Plasmapheresis in treatment of Myasthenia Gravis: a systematic review

2021 ◽  
Author(s):  
Isabella Delfim de Carvalho ◽  
Felipe Iankelevich Baracat ◽  
Lucas Farina Lima
Keyword(s):  
Systematic Review ◽  
Myasthenia Gravis ◽  
Therapeutic Option ◽  
Length Of Hospital Stay ◽  
Treatment Phase ◽  
Ivig Therapy ◽  
Myasthenic Crisis ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration ◽  
Result Analysis

Introduction: Myasthenia Gravis (MG) is an autoimmune and neuromuscular disease. The treatment of immunomodulation consists of intravenous immunoglobulin (IVIg), immunoadsorption (IA), plasmapheresis (PLEX) or double filtration plasmapheresis (DFPP). This systematic review aims to compare therapy modalities in MG crisis. Methods: The studies were identified through research in electronic databases and analyzed individually to clarify their methodological quality (through the Jadad and Newcastle Ottawa scale). Clinical trials randomized or not, and retrospective studies were included. The review included 1,983 patients in nine studies, the result analysis groups were divided into: IVIg x PLEX in the crises; IVIg x PLEX in the pre-thymectomy treatment phase and IVIg x DFPP in the myasthenic crisis. The evaluated outcomes were clinical improvement, adverse effects and length of hospital stay. Results: Immunomodulatory therapy when applied prior to thymectomy was shown to be effective in reducing symptoms and post-thymectomy hospitalization, with IVIg slightly higher, while PLEX showed more side effects. Therapy during crises in both interventions proved to be effective after the 14th start of treatment, in addition to IVIg being slightly superior. Treatment with IVIg was also economically favorable, due to the lower need for hospitalizations. IVIg proved to be inferior to therapy with DFPP and IA, mainly in reducing the need for hospitalization. Conclusion: It is concluded that IVIg therapy is a good therapeutic option in cases of crisis and when available, therapies with DFPP and IA should be the choices, aiming at less complications.

scholarly journals A case of refractory myasthenia gravis positive for anti MuSK antibody that was successfully treated with double filtration plasmapheresis

2007 ◽  
Vol 40 (6) ◽  
pp. 531-535
Author(s):  
Jun Nakagawa ◽  
Takashi Muramatsu ◽  
Keiko Ohta ◽  
Minoru Ando
Keyword(s):  
Myasthenia Gravis ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration

scholarly journals Myasthenia Gravis with Anti-Muscle-Specific Tyrosine Kinase Antibody during Pregnancy and Risk of Neonatal Myasthenia Gravis: A Case Report and Review of the Literature

2020 ◽  
Vol 12 (1) ◽  
pp. 114-120
Author(s):  
Ken-ichi Inoue ◽  
Jun Tsugawa ◽  
Jiro Fukae ◽  
Kosuke Fukuhara ◽  
Hiroyasu Kawano ◽  
...  
Keyword(s):  
Case Report ◽  
Tyrosine Kinase ◽  
Myasthenia Gravis ◽  
Upper Limb ◽  
High Probability ◽  
Oral Steroid ◽  
Review Of The Literature ◽  
Limb Weakness ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration

A 31-year-old woman presented with a nasal voice, dysarthria, and upper limb weakness during her first pregnancy. Soon after delivery of her first baby, her symptoms disappeared. At the age of 34 years, during her second pregnancy, her nasal voice re-appeared. After delivery of the second baby, her nasal voice worsened, and bilateral eyelid ptosis and easy fatigability were also evident. She was referred to our hospital. Because of her myasthenic symptoms and anti-muscle-specific tyrosine kinase (MuSK) antibody (Ab)-positive status, she was diagnosed as having myasthenia gravis (MG). Her symptoms were worse than those in her first pregnancy. She was treated with oral steroid and double filtration plasmapheresis. After initiation of treatment, her myasthenic symptoms improved completely. In addition, her baby developed transient neonatal MG (TNMG) on the fourth day after birth and then gradually recovered over 30 days. It should be noted that symptoms of patients with anti-MuSK Ab-positive MG (MuSK-MG) can deteriorate during pregnancy, and the babies delivered of patients with MuSK-MG have a high probability of developing TNMG.

Comparative Study of Clinical Effects Between Plasma Adsorption and Double Filtration Plasmapheresis in Patients with Myasthenia Gravis

1997 ◽  
Vol 1 (4) ◽  
pp. 343-347 ◽  
Author(s):  
Hirokazu Okada ◽  
Kenshi Moriwaki ◽  
Souichi Sugahara ◽  
Hidetomo Nakamoto ◽  
Takeshi Hosokawa ◽  
...  
Keyword(s):  
Comparative Study ◽  
Myasthenia Gravis ◽  
Clinical Effects ◽  
Double Filtration Plasmapheresis ◽  
Double Filtration
Sign in / Sign up

Export Citation Format

Share Document