Pharmacokinetic Study of Intravenous Acetaminophen Administered to Critically Ill Multiple-Trauma Patients at the Usual Dosage and a New Proposal for Administration

2017 ◽  
Vol 57 (10) ◽  
pp. 1345-1352 ◽  
Author(s):  
Oscar Fuster-Lluch ◽  
Pedro Zapater-Hernández ◽  
Manuel Gerónimo-Pardo
Keyword(s):  
Multiple Trauma ◽  
Critically Ill ◽  
Pharmacokinetic Study ◽  
Trauma Patients ◽  
Intravenous Acetaminophen ◽  
Multiple Trauma Patients ◽  
Usual Dosage

Treatment of Acute Hypocalcemia in Critically Ill Multiple-Trauma Patients

2005 ◽  
Vol 29 (6) ◽  
pp. 436-441 ◽  
Author(s):  
Roland N. Dickerson ◽  
Laurie G. Morgan ◽  
April D. Cauthen ◽  
Kathryn H. Alexander ◽  
Martin A. Croce ◽  
...  
Keyword(s):  
Multiple Trauma ◽  
Critically Ill ◽  
Trauma Patients ◽  
Multiple Trauma Patients

INFLUENCE OF SEDATION ON MORTALITY IN CRITICALLY ILL MULTIPLE TRAUMA PATIENTS

The Lancet ◽  
1983 ◽  
Vol 321 (8336) ◽  
pp. 1270 ◽  
Author(s):  
I LEDINGHAM
Keyword(s):  
Multiple Trauma ◽  
Critically Ill ◽  
Trauma Patients ◽  
Multiple Trauma Patients

Influence of traumatic brain injury on potassium and phosphorus homeostasis in critically ill multiple trauma patients

Nutrition ◽  
2010 ◽  
Vol 26 (7-8) ◽  
pp. 784-790 ◽  
Author(s):  
Kimberly A. Lindsey ◽  
Rex O. Brown ◽  
George O. Maish ◽  
Martin A. Croce ◽  
Gayle Minard ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Multiple Trauma ◽  
Critically Ill ◽  
Trauma Patients ◽  
Multiple Trauma Patients

Minute-to-minute urine flow rate variability: a retrospective survey of its ability to provide early warning of acute hypotension in critically ill multiple trauma patients

2019 ◽  
Vol 46 (5) ◽  
pp. 1175-1181
Author(s):  
Evgeni Brotfain ◽  
Yoram Klein ◽  
Ronen Toledano ◽  
Micha Yitzhak Shamir ◽  
Leonid Koyfman ◽  
...  
Keyword(s):  
Multiple Trauma ◽  
Critically Ill ◽  
Flow Rate ◽  
Early Warning ◽  
Urine Flow ◽  
Urine Flow Rate ◽  
Trauma Patients ◽  
Retrospective Survey ◽  
Acute Hypotension ◽  
Multiple Trauma Patients

Evaluation of an Artificial Neural Network to Predict Urea Nitrogen Appearance for Critically Ill Multiple-Trauma Patients

2005 ◽  
Vol 29 (6) ◽  
pp. 429-435 ◽  
Author(s):  
Roland N. Dickerson ◽  
Darius L. Mason ◽  
Martin A. Croce ◽  
Gayle Minard ◽  
Rex O. Brown
Keyword(s):  
Neural Network ◽  
Artificial Neural Network ◽  
Multiple Trauma ◽  
Critically Ill ◽  
Trauma Patients ◽  
Urea Nitrogen ◽  
Artificial Neural ◽  
Multiple Trauma Patients ◽  
Urea Nitrogen Appearance

scholarly journals Clinical outcomes of critically ill multiple trauma patients with rib fractures. A prospective study with retrospective control

2020 ◽  
Author(s):  
Asaf Acker ◽  
Evgeni Brotfain ◽  
Leonid Koyfman ◽  
Michael Friger ◽  
Yael Refaely ◽  
...  
Keyword(s):  
Prospective Study ◽  
Clinical Outcomes ◽  
Multiple Trauma ◽  
Critically Ill ◽  
Rib Fractures ◽  
Trauma Patients ◽  
Multiple Trauma Patients ◽  
A Prospective Study

scholarly journals The clinical significance of hyperglycemia in nondiabetic critically ill multiple trauma patients

2018 ◽  
Vol 9 (8) ◽  
pp. 223-230 ◽  
Author(s):  
Leonid Koyfman ◽  
Evgeni Brotfain ◽  
Dmitry Frank ◽  
Yoav Bichovsky ◽  
Inna Kovalenko ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Blood Glucose ◽  
Intensive Care Unit Stay ◽  
Multiple Trauma ◽  
Critically Ill ◽  
Clinical Significance ◽  
Trauma Patients ◽  
Ventilator Associated Pneumonia ◽  
Multiple Trauma Patients

Background: Information is inconsistent regarding the clinical role of acute elevations of blood glucose level secondary to hospital-acquired infections in nondiabetic critically ill patients during an intensive care unit stay. In this study we investigated the clinical significance of hyperglycemia related to new episodes of ventilator-associated pneumonia in nondiabetic critically ill multiple trauma intensive care unit patients. Materials and Methods: We analyzed the clinical data of 202 critically ill multiple trauma patients with no history of previous diabetes who developed a new ventilator-associated pneumonia episode during their intensive care unit stay. We used a time-from-event analysis method to assess whether acute changes in blood glucose levels that occurred prior to the onset of ventilator-associated pneumonia episodes had a different prognostic significance from those that occurred during such episodes. Glucose levels and other laboratory data were recorded for up to 5 days before ventilator-associated pneumonia events and for 5 days following these events. Results: Patients who required insulin therapy for persistent hyperglycemia related to a new ventilator-associated pneumonia event had a longer period of intensive care unit stay and a higher intensive care unit mortality rate than patients who did not require insulin for blood glucose control ( p < 0.008 and <0.001 respectively). In addition, older age, administration of parenteral nutrition, and elevated mean blood glucose level parameters on the day following the day of diagnosis of a new ventilator-associated pneumonia episode were found to be independent risk factors for intensive care unit mortality. Conclusion: Our study suggests that persistent hyperglycemia in nondiabetic critically ill patients, even treated by early insulin therapy, is an adverse prognostic factor of considerable clinical significance.

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